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Biomedical subjects

W Mann

Publications and source records attributed to W Mann.

At least 217 records · Page 12Linked to original sources
PubMed1980

[Epidemiology and bacteria in infectious sinus diseases (author's transl)].

A number of studies show that only a few bacteria are dominating the infectious sinus diseases. In acute sinusitis hemophilus and pneumococci are prevalent. Recent results in chronic sinusitis indicate a greater importance of anaerobic bacteria. The bacteriological findings in sinusitis are influenced by many factors: 1. the sampling techniques (proof-puncture or nasal-swab); 2. transport time and transport medium; 3. bacteriological culture technique; 4. the isolated bacteria are not automatically pathogens. The difference between colonizing or contaminating bacteria and pathogenic bacteria should be taken into account. A lack of leukocytes, a mixture of bacteria and a viable count of 10(3) or lower indicates normal flora or contamination; 5. kind of infection: acut - chronic; dentogen - rhinogen; 6. mode and duration of therapy (antibiotics, surgery, irrigation); 7. age of patient, season of the year.

Bacterial Infections↗
PubMed1980

[Lymphatic drainage of the maxillary sinus (author's transl)].

The lymphatic drainage of the maxillary sinus has been evaluated by means of lymphangioscopy. Besides the ostial route of lymphatic drainage, there are connection over the pterygo-palatine plexus to the eustachian tube and the nasopharynx. The clinical significance for spread of tumor or infections via this route is discussed.

Adult↗
PubMed1980

[Diagnostics in infectious sinus diseases (author's transl)].

Various diagnostic methods and their validity in infectious sinus disease are discussed, i.e. history and clinical examination, proofpuncture and lavage, transillumination, x-ray, manometry, viscosimetry, ultrasound, endoscopy and computerized tomography.

Bacterial Infections↗
PubMed1980

[Recurrencies in oropharyngeal, hypopharyngeal and supraglottic squamous-cell carcinomas (author's transl)].

80 patients with recurrent carcinomas of the oropharynx, hypopharynx and supraglottis were examined. Average recurrency occured after 15,1 months. 10 patients showed first and 3 patients second recurrent carcinomas on the mucous membranes of the upper respiratory tract. All the recurrencies were located distant from the primary tumor site, within the irradiation field and most of the times contralaterally. Lymphatic vessel damage and inversion of the regular lymphatic drainage are discussed for their etiological role.

Carcinoma, Squamous Cell↗
PubMed1980

[Hereditary angioneurotic edema (author's transl)].

Hereditary angioneurotic edema is a rare autosomally-inherited disease, which is caused by a deficiency or functional inactivation of C-1 inactivator in the complement system. The poor prognosis of the disease mandates that an early diagnosis be made and drug therapy begun to prevent a lethal outcome. The pathogenesis, clinical course and therapies available are detailed.

Angioedema↗
PubMed1980

[Viscosity studies of tracheobronchial secretions post tracheostomy (author's transl)].

In 14 patients post tracheostomy viscosity of the tracheobronchial secretion was studied. No daytime fluctuation of the viscosity could be detected. There was a clear correlation between viscosity and duration since tracheostomy. Infection had less impact on viscosity than the appearance of mucous structures. antibiotics decreased, ionizing radiation of the patient increased viscosity. Humidification of the inspired air by means of an "artificial nose" increase volume and viscosity of the secretions.

Aged↗
PubMed1979

Effect of temperature on the transcription by bacteriophage T3-induced RNA polymerase.

Bacteriophage T3-induced RNA polymerase is rapidly inactivated at 42 degrees C. Addition of T3 DNA delays this process for 30 s and reduces the rate with which the enzyme activity is lost indicating that a labile binary complex between T3 DNA and polymerase must have been formed. The ternary complex between T3-specific RNA polymerase, T3 DNA, and nascent RNA chains obtained when the enzyme is incubated with T3 DNA, GTP, ATP, and UTP is stable to heat (42 degrees C) and only slowly inactivated by polyvinyl sulfate. The optimal temperature for the formation of polyanionresistant ternary complexes is 30 degrees C while the elongation of T3 RNA chains proceeds fastest at 38 degrees C.

Cell-Free System↗
PubMed1979

[The lymphatic system of the larynx. A lymphangioscopic and ultrastructural study (author's transl)].

From post mortem and in vivo tissues, the lymphatic drainage of the human larynx has been evaluated by means of lymphangioscopy. The fine structure of lymphatic capillaries and collecting vessels was examined in an electron microscope study. At the ultrastructural level, the structural components of the laryngeal lymphatic vascular wall showed only minor differences when compared to other lymphatic tissues. These differences concerned the valvular morphology of the lymphatic collecting vessels. There was no evidence of specific lymphatic drainage for distinct laryngeal areas, with the exception of the lymphatic capillaries of the free margin of the vocal cords. On account of anastomoses of lymphatic capillaries and collecting vessels lymphatic drainage could cross over both the laryngeal midline and other laryngeal levels. In pathological conditions with impediment of lymphatic flow, these collateral communications are of clinical significance.

Adult↗
PubMed1979

Indirect measurement of laryngeal and tracheal resistance.

We used a body plethysmograph to determine airway resistances in 485 cases of laryngeal and tracheal stenoses. 143 cases who had resistances exceeding 60 mm H2O/l.a.sec underwent surgery. A vocal cord was laterally fixed in 49 patients suffering from bilateral recurrent paralysis. Optimal results were obtained at a postoperative resistance level of 30 mm H2O/l.a.sec (standard value: 14.77 +/- 6.53 - n - 387). The patients could carry out work of medium intensity and had a steady voice. We performed tracheal interventions in 94 cases of tracheal stenoses. A mean postoperative resistance of 29.9 mm HWO/l.a.sec, with a tracheal diameter of 7-8 mm was attained. In practice, only a few patients found the remaining obstruction a hindrance, during work of maximal intensity. No recurrences were observed after treatment. Airway resistance exceeding 150 mm H2O/l.a.sec were found in 13 new admissions and 73 times in those undergoing therapy. In these cases asphyxiation threatens. These patients must be tracheotomized or intubated immediatly.

Airway Resistance↗
PubMed1979

Diagnostic ultrasonography in paranasal sinus diseases. A 5-year review.

Ultrasonography is a useful diagnostic tool in the evaluation of patients with paranasal sinus disease. It is a simple, reliable method with a failure rate of approximately 10%. The increasing use of this diagnostic tool requires the reemphasis and prevention of possible errors in establishing the correct diagnosis.

Diagnosis, Differential↗
PubMed1979

[Prostaglandins in skin blisters of bullous erysipelas, dermatitis herpetiformis and herpes gestationis (author's transl)].

The PGE2 and PGF2 alpha content of bullae developing spontaneously on the skin was investigated by radioimmunoassay in 12 patients with different skin diseases. The PGF2 alpha level was also established in the plasma and urine. In herpes gestationis, dermatitis herpetiformis and bullous erysipelas the PGE2 and PGF2 alpha content of the bullae considerably exceeded the plasma and urinary PG levels. The findings were thought to be in relation with the acute inflammation of the skin, the mechanism of bulla formation as well as with pruritus.

Adult↗
PubMed1979

Ostium resistance in acute maxillary and frontal sinusitis.

Ostium function tests were performed in 18 normal maxillary and 6 normal frontal sinuses. Further 57 patients with acute maxillary and 16 patients with acute frontal sinusitis were followed using sinumanometry until resolution of infection occured. After initial obstruction of the ostium, resistance decreased exponentially until complete decongestion. Respiratory pressure changes in the sinus during forced nasal breathing are a positive sign for healing of sinusitis. The amplitude of these fluctuations should be documented during each lavage and facilitates indication for drainage procedures.

Adult↗
PubMed1979

The indirect measurement of laryngeal and tracheal resistance.

We used a body-plethysmograph to determine air-way resistances in 485 cases of laryngeal and tracheal stenoses. We decided in 143 cases to intervene after observing resistance exceeding 60 mm H2O/l and sec. A vocal chord was lateral fixated in 49 patients suffering bilateral recurrent paralysis. Optimal results were obtained at a postoperative resistance level of 30 mm H2O/l and sec (standard value: 14.77+/-6.53--n = 387). The patients could carry out work of medium intensity and had a steady voice. We performed tracheal interventions in 94 cases of tracheal stenoses. A mean, post-operative resistance of 29.9 mm H2O/l and sec, with a tracheal diameter of 7--8 mm was attained. In practice, only a few patients found the remaining obstruction a hindrance during work of maximal intensity. No recurrences were observed after treatment. Airway resistances exceeding 150 mm H2O/l and sec were found in 13 new admissions and 73 times in those undergoing therapy. In these cases asphyxiation threatens. These patients have to be tracheotomized or intubated immediately.

Airway Resistance↗