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Biomedical subjects

W Land

Publications and source records attributed to W Land.

At least 199 records · Page 11Linked to original sources
PubMed1985

Fine-needle antegrade pyelography of transplanted kidneys.

Ureteral obstruction or perforation must be considered as a cause of poorly functioning renal transplants. Sonography and radionuclide scanning will demonstrate outflow obstruction and/or pararenal fluid collection, but do not usually provide sufficient information on the site of the lesion. In these cases we have successfully used fine-needle puncture of the renal pelvis under sonographic guidance, and antegrade pyelography. This technique shows excellent anatomical details of the renal pelvis and ureter.

Graft Rejection↗
PubMed1985

[Cytomegalovirus infection after kidney transplantation--importance of the primary infection].

Even though for many reasons (shortage of organs, histocompatibility, lack of time to await the results) an organ transplantation from a sero-positive donor to a sero-negative recipient will not be unavailable, CMV-serology should be checked as early as possible, if possible even before transfusions or their donors since the virus remains infectious over several weeks in the leucocytes. The prophylactic use of hyperimmunoglobulin is justified in cases where organs or blood from sero-positive donors are given to sero-negative immunosuppressed patients because complications arising from the infection can be life-threatening in these patients.

Antibodies, Viral↗
PubMed1985

Progression of coronary and valvular heart disease in patients on dialysis.

Coronary heart disease and end-stage renal disease: Coronary heart disease is frequent in patients with end-stage renal disease. Without invasive procedures coronary heart disease is often not diagnosed in patients with end-stage renal disease. We have no evidence for accelerated progression of coronary heart disease under conditions of dialysis. Valvular heart disease and end-stage renal disease: Valvular heart disease shows an increasing frequency depending on the period of dialysis. Valvular heart disease is often unnoticed and constantly underestimated without invasive investigation. Valvular heart disease often indicates a bad prognosis in our patients with end-stage renal disease.

Adult↗
PubMed1985

Organ procurement in Munich: financial and organizational aspects.

The Transplantation Center at the University of Munich is like all other German centers financially supported by the Insurance Companies via a non-profit organization (Kuratorium für Heimdialyse e.V.). The financial modalities are based on the arrangement that the Insurance Companies pay a certain amount for each transplantation to the non-profit organization. This institution, in cooperation with the University, uses this money to cover all extra expenses arising in the field of organ procurement as well as clinical transplantation (providing additional staff, equipment, etc). This model of a transplant center (ie, cooperation between University and non-University institutions) proved to be successful in the past 9 years. There was a steady increase of donor nephrectomies (200 donor kidneys in 1984) as well as kidney transplantations (171 transplantations in 1984).

Cadaver↗
PubMed1985

[Combined immunosuppression (cyclosporin, azathioprine, methylprednisolone) in patients at immunological risk after kidney transplantation].

Animal experiments have demonstrated a synergistic immunosuppressive effect when using the combination of ciclosporin (CS) and azathioprine (AZA) as immunosuppressant. On this basis these drugs were used in patients considered to be at high risk for immunological complications. Group I (immunological risk patients) consisted of 63 patients with a second or third graft and/or elevated cytotoxic antibodies above 30% against the test panel. In addition to the basic immunosuppressive therapy (CS) and methylprednisolone (MP), AZA was given in the first 2 weeks following transplantation. Group II (historical control) summarized immunological risk patients with conventional immunosuppressive therapy (AZA/MP). The IIIrd group with 28 patients on the above mentioned immunological risk were treated with CS and MP only. The results revealed a 2-year actuarial graft survival rate of 68% (groups I) versus 40% (group II) versus 52% (group III). There were no differences in WBC and platelet counts or in infectious complications. No malignancy was noticed.

Azathioprine↗
PubMed1984

Spleen transplantation in the dog as a model for studying immunological feedback reactions.

Modification of the immune response towards the generation of suppressor T cells can be attained using experimental designs promoting immunological feedback mechanisms. Those studies have been carried out in defined inbred animal systems. With respect to the great importance for organ transplantation, an in vivo model using larger outbred animals was developed in order to study such feedback reactions. The following experimental design was used: (1) allogeneic spleen transplantation in the dog; (2) autologous retransplantation of this spleen together with an allogeneic kidney transplantation to the former donor of the spleen after a period of 2-4 days. Although full immunological activity of the transplanted as well as the retransplanted spleen was demonstrated, rejection of the kidney occurred in a fashion identical to that observed in control animals.

Animals↗
PubMed1984

[Transient neurogenic bladder-emptying disorder caused by herpes genitalis following kidney transplantation].

We report on a case of transient neurogenic dysfunction of the urinary bladder caused by herpes genitalis in a renal transplant patient. The patient noticed a slow urinary stream 3 days after the vesicular stage of the herpes genitalis. After 9 days complete urinary retention and loss of sensation developed, necessitating the insertion of suprapubic tube. Symptoms and residual urine spontaneously disappeared after 20 days. After removal of the suprapubic tube the patient could empty his bladder completely with good stream. 45 cases of this kind have been described in the literature. the cause is a sacral meningo-radiculitis with herpes simplex virus leading to a transient neuromotoric paralysis of the bladder.

Adult↗