Chronic Epstein-Barr virus reactivation after renal transplantation: immunosuppression with cyclosporine versus azathioprine.
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Biomedical subjects
Publications and source records attributed to W Land.
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Postrenal obstruction is a severe complication after renal transplant. To evaluate side effects and effectiveness we analyzed 71 ategrade pyeloureterographies (AP) and 30 percutaneous and open nephropyelostomies. AP shows a sensitivity of 93% and proved thereby its superiority to alternative diagnostic procedures. Also percutaneous pyelostomy proved its reliability in therapy of obstructive disease. Comparing side effects to those in normal kidneys we found a higher incidence of bleeding (17%). There was no severe complication with loss of graft. In 6 cases of obstructive disease we could prevent an operation by temporary percutaneous nephrostomy. Long term nephrostomy allows to evaluate the function of the kidney accurately which may not be possible until after 1-2 months.
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The authors report their data relating to the first combined kidney-pancreas transplants performed at the Munich University Transplant Centre in the years 82-84 and discuss the main technical aspects of explantation and implantation surgery in these cases as well as the results obtained.
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The authors analyze the advances made and the current state of the art in transplant medicine and surgery, dealing at some length with the problems relating to organ donation. Particular attention is devoted to the provisions of law currently applicable in this field and those aspects currently under debate, comparing the situation in Italy with that obtaining elsewhere in Europe. The authors also focus on the need to make medical practitioners fully aware of the problem so as to achieve practical collaboration of the type possible today in West Germany.
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