[Diagnostic methods in the evaluation of thyroid gland function in patients with goiter during preparation for surgery].
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Biomedical subjects
Publications and source records attributed to W Lambrecht.
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Our experiences with organ saving procedures of the spleen in childhood are presented. In 9 out of 12 children (75%) with traumatic rupture we preserved the organ partially or completely. In 4 patients a partial splenectomy was performed, in three cases of splenorrhaphy was done, and once the organ was repaired with fibrin adhesive. One child was treated conservatively. Another patient underwent splenectomy followed by autotransplantation. Two out of twelve died intra- or postoperatively from severe concomitant injuries. Out of 11 patients with Hodgkin's disease we performed partial splenectomy in five. Only in macroscopically involved cases the organ was removed. In one patient a huge epidermoid cyst of the spleen was enucleated. In another child with a big twisted wandering spleen a splenopexy after partial resection was carried out. In children the spleen should be preserved if ever possible.
The torsion of an ectopic (= wandering) spleen is a rare entity especially in children. Clinically it presents either with signs of an "acute abdomen" or as a fairly painful abdominal "tumor" of the chronic recurrent type. Ultrasonography, arteriography, and additional scintigraphy in special cases are of greatest value in the preoperative diagnostic management. Splenopexy, sometimes after resecting parts of a very enlarged organ, is the therapy of choice. The complete exstirpation of the ectopic spleen should be reserved only for exceptional cases. By presenting a case report, the etiologic factors, the clinical signs, the diagnostic steps, the differential diagnostic considerations as well as the mode of therapy for this rare disease are described and discussed.
Splenectomized patients--especially children - run the risk of a possibly lethal postoperational sepsis. Therefore an extirpation of the ruptured spleen should be avoided, if possible. Six children treated for a rupture of this organ within the last 2 1/2 years are presented in order to describe the diagnostic proceeding in case of suspected spleen rupture as well as the possible conservative treatment and the different surgical possibilities. The spleen could be preserved in five children.
In a 16-year-old girl who suffered from non-characteristic upper abdominal complaints, the gastrointestinal passage revealed an extreme megaduodenum associated with nonrotation. Intraoperatively, congenital adhesions were found as cause which had stenosed the duodenojejunal transition and had become fixed in the right upper abdomen. After separating the adhesions, resecting the stenosis and narrowing the duodenum, intestinal continuity was restored by means of an end-to side duodenojejunostomy. The causes, signs, diagnosis and therapy of the megaduodenum are discussed.
Two infants aged four and eight weeks required an operation for an interstitial inguinal hernia. The clinical picture of this rare form of hernia is characteristic. There is a swelling in the abdominal wall between the internal inguinal ring and the anterior superior iliac spine. In addition there is almost always an ectopic testis on the affected side. Incidence, clinical picture and anatomy of the interstitial hernia are discussed.
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The computer tomographic appearances of 16 traumatic lesions of the spleen have been analysed. The changes n the spleen were related to the subsequent therapeutic procedures. The clinically important distinction between parenchymal rupture and parenchymal-capsular rupture can always be made with certainty. CT also adds information concerning parasplenic abnormalities, traumatic changes in upper abdominal organs and additional injuries to other parts of the body.
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A 10-year-old girl was operated because of an epidermoid cyst of the spleen weighing 2 kilograms. The cyst was enucleated and the spleen reconstructed. This procedure is seen as the operation of choice as the development of post-splenectomy sepsis can thus be prevented.
Total aganglionosis of the colon presenting with small intestinal obstruction in the neonatal period was observed in combination with congenital alveolar hypoventilation requiring continuous mechanical ventilation in a boy. The patient died aged 15 months from acute dehydration due to enteritis, long after total resection of the aganglionic bowel had been performed. Pulmonary hypertension was found in the newborn period. There was progressive right ventricular myocardial hypertrophy. This is the fourth case reported with a combination of defects involving nerve cell function of the brain stem and gastrointestinal tract.
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A 3 1/2-year-old girl with multiple hemangiomas of the skin developed a severe anemia soon after birth due to intestinal hemorrhage. She required multiple blood transfusions for the next 3 years. At the time of operation 32 hemangiomas in the duodenum, small and large bowel were resected. The postoperative course was uneventful, the child had no further blood less. An extensive hemangioma in the lower esophagus was left in place.
Mesenteric cysts belong to the rare abdominal diseases. Histomorphologically, they are classified as cystic lymphangiomas. Even though most frequently localized in the mesentery of the small intestine, they can originate from any part of the abdominal cavity with two peritoneal linings. The content of the cysts is either serous or chylous possessing immunologic active proteins. This is demonstrated by its highly antibacterial activity. Whereas in children the onset of symptoms is acute due to intestinal obstruction, in adults it is mainly chronic abdominal pains without exact localisation and often in combination with a longstanding palpable tumour. In addition to routine procedure the diagnostics includes sonography, cavography and barium meal radiography of the stomach and intestines. In some cases, especially those with solid parts angiography and computer-tomography are of additional value. Surgery is the therapeutic method of choice. Preference is given to enucleation and resection with or without removal of part of the intestine corresponding to the mesentery baring the cyst. Drainage methods are of historical interest only. In our 9 cases (3 children and 6 adults) resection was performed in 7 and enucleation in 2 cases. The postoperative courses were uneventful.
The influence of levamisol (1, 2, 3, 5, 6-tetro hydro-6-phenylimidasole 2,1-6 thiasol) on the survival time of allogenic skin grafts was examined in healthy rabbits and in rabbits with a burn disease. The survival time of the transplants was prolonged significantly in healthy rabbits and diminished in rabbits with burn disease.
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