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Biomedical subjects

W L Qiu

Publications and source records attributed to W L Qiu.

102 records · Page 6Linked to original sources

[Comparative study on healing process between vascularized and non-vascularized autogenous bone grafts]

This study made a histological comparison (light microscope and transmission electron microscope) between vascularized bone graft (VBG) and non-vascularized bone graft (NVBG) in mandible of dog.The study showed:the healing process of VBG was the same as that of bone fracture.The "creeping substitution" process of NVBG was imbued with the inflammation induced by dead bone.There was no significat difference on the bone union between VBG and NVBG perhaps for the recipient region was better vascularized.

Journal Article↗

Treatment of cleft lip and cleft palate.

The first case of cheiloplasty recorded was in China at about 200 BC. The technique of course has been vastly improved over the centuries. Cleft lip and/or cleft palate are among the most common congenital anomalies in China and the world. There is controversy over some of the surgical techniques used and age for operation, especially in cleft palate, but the condition requires surgery. Unilateral cleft lip is operated on at 3-6 month of age and bilateral cleft lip at 6-12 month of age. Views on palatoplasty are: 1. Cleft palate should be repaired at an early age; 2. Supplementary orthodontic treatment to expand the upper arch postoperatively is necessary, and orthognathic surgery is performed if needed when the patient has matured. This is the best choice at present.

China↗

[A preliminary experience of chemotherapy using cisplatin (CDDP) in oral and maxillofacial carcinoma].

During 1984-1986, fifty-one patients, including 42 squamous cell carcinomas, 8 carcinomas of salivary gland origin and 1 malignant histiocytoma, were treated in our hospital using the PVP (CDDP, VCR and PINGYANGMYCIN) regimen or single CDDP. The response rate was 71.4% (30/42) for squamous cell carcinoma (CR 4 cases, PR 26 cases, NR 12 cases) with PVP, and 3/8 (all PR cases) for carcinoma of salivary gland origin (all adenoid cystic carcinomas) with CDDP. The authors indicate that besides the MTX and PINGYANGMYCIN, CDDP is another effective and useful drug for squamous cell carcinoma. When single dose (80-120 mg) is given by infusion with fluid and diuretics, it is very safe and (no need) worry about impairment of kidney function.

Adult↗

Treatment of habitual dislocation of the temporomandibular joint with subsynovial injection of sclerosant through arthroscope.

Five patients with habitual dislocation of the temporomandibular joint (TMJ), failing in conservative therapy, were treated with subsynovial injections of sclerosant through an arthroscope, and this treatment was proved to be effective over the short-term. Compared with operation, this method is easily performed and produces less damage and no significant sequelae, but the long-term effects have yet to be observed.

Adult↗

[Kinetics of the thermotolerance of human tongue squamous cell carcinoma cells (Tca 8113) in vitro].

This paper reports an observation on kinetics of induction and resolution of the thermotolerance expressed by Tca8113 in vitro in form of colony-forming rate, synchronization and laser flow cytometry after the cells being exposed to continuous and fractionized heat treatment of 41.5-45.5 degrees C for 4 hours. The process of thermotolerance kinetics could be divided into three phases: triggering, development and decay. The triggering phase lasted about 8 hours. The duration of development and decay phases was related to the temperature of initial heating. The higher the temperature, the shorter the duration. Generally, thermotolerance gradually disappeared 96 hours after the initial heating treatment. The thermotolerance of the synchronized cells in various phases was G1 greater than G2 greater than M greater than S. Hyperthermia simultaneously combined with pingyangmycin both produces a greater synergetic cytotoxic effect and reduces the degree of thermotolerance.

Antibiotics, Antineoplastic↗

Evaluation of free flaps transferred by microvascular anastomosis in oral and maxillofacial surgery.

The authors discuss indications for the use of microvascular free flaps transferred to the oral and maxillofacial region. A series of 139 cases, involving 145 free flaps, is reported over a three year period. The overall success rate for all types of flaps was 89.3%. Advantages and disadvantages of the use of various flaps are presented and suggestions are offered to avoid complications.

Adolescent↗