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Biomedical subjects

W Klug

Publications and source records attributed to W Klug.

At least 55 records · Page 3Linked to original sources

[Animal experimental scintigraphic studies of closed lower leg fractures during the 1st 24 hours following the fracture trauma].

A closed fracture in the medium third part of the tibia was carried out in 50 rabbits. The scintigraphy was performed in groups of 5 animals at a time 2, 4, 6, 10, 12, 14, 16, 18, and 24 hours after the fracture trauma, in each case 45 minutes after the injection of 8 MBq 99mTc diphosphonat per kg body weight. The ROI activity quotient of both shank diaphysis was analysed. The first ascent was observed at the tenth postoperative hour. The ROI activity quotient was 2.1 24 hours after the fracture trauma. No marking of the fracture area was observed but an increase of the activity altogether above the diaphysis, and no ascent of the activity quotient in the neighbouring joints was observed.

Animals↗

[The influence of ergonovine on coronary artery diameter and hemodynamics in patients with angina pectoris at rest (author's transl)].

The influence of methyl ergonovine on coronary artery diameter and regional ventricular function was studied in three groups of patients with and without suspected coronary artery spasm. Ten patients with angina at rest in whom spasm was suspected were compared to seven coronary heart disease patients with stable effort angina. Six patients without coronary heart disease served as controls. Ergonovine, an agent known to cause coronary vasoconstriction, was administered in order to identify the possible role of spasm in the various subgroups. The standardized study procedure comprised coronary and left ventricular angiography before and after 0.1 to 0.4 mg ergonovine i.v. as well as after 1.6 mg nitroglycerin sublingually. Following ergonovine provocation, narrowing of the anterior descending branch averaged 22 per cent in the patient group with suspected spasm, 3 per cent in patients with coronary heart disease, and 6 per cent in the control group. The spasm group also displayed regional ventricular hypokinesis and an increase in endsystolic volume. LVEDP increased from 15 +/- 6 to 28 +/- 7 mm Hg (p < 0.0005) mean circumferential fiber shortening (mean Vcf) decreased from 1.6 +/- 0.4 to 1.1 +/- 0.4 circ/s (p < 0.0025), and the velocity of shortening in the anterior apical hemiaxis (Vm3) declined from 1.9 +/- 0.2 to 0.8 +/- 0.4/s (p < 0.0005). These changes were much less evident in the coronary heart disease group. No significant hemodynamic changes were observed in the control group. Patients with angina at rest are much more susceptible to ergonovine-induced coronary artery narrowing than patients with stable exertional angina.

Adult↗

[Significance and evaluation of gingival and bony pockets].

The reproducibility of measurements of gingival pocket depth was tested on a total of 200 patients and assessed by statistical analysis. Significantly differing values were observed only in the region of the upper molars, whereas consistent values were found in all the other regions. The measurement of pocket depth is an easy-to-determine reproducible parameter in periodontal diagnostics. A gross information about the presence and depth of intrabony pockets cannot be obtained from clinical values for pocket depth.

Gingival Pocket↗