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Biomedical subjects

W Huk

Publications and source records attributed to W Huk.

60 records · Page 4Linked to original sources

[Computer tomography for abnormalities of the skull base and orbits: combined use of horizontal and frontal sections (author's transl)].

The cases of seven patients with different lesions of the base of the skull and the orbits are demonstrated, where CT was performed in horizontal and coronal sections. The results make obvious that only the combination of both planes can provide optimal information in these cases. The existence of a basal or orbital lesion, its size and location, and whether or not it penetrates through the base of the skull, can easily be detected. This is of great help in determining the therapy of choice, i.e. operability or radiation therapy treatment planning.

Adult↗

Peripheral nerve stimulation by time-varying magnetic fields.

PURPOSE: A study was performed to assess the stimulation threshold for healthy adults using sinusoidally oscillating gradients. METHOD: One hundred thirteen healthy adults were examined in the study. ECG and physiological parameters were measured. All measurements were performed of both the head and the abdomen. The subjects were measured in the supine position with the region of interest positioned in the center of the gradient coils. The measurement was performed for three orthogonal, four oblique, and double oblique orientations. RESULTS: No volunteer reported painful, severe stimulation. The mean thresholds for peripheral stimulation in head and body measurement were similar: 85.5% of stimulation during examination of the head and 87.6% during measurements of the abdomen were reported when the y-gradient was used. CONCLUSION: The greatest frequency of reported stimulations occurs when the y-gradient is used. This was confirmed by the results and supports the hypothesis that orthogonal to the y-axis the body has its largest conductive loop, resulting in the strongest peripheral stimulation.

Adult↗

The significance of bilateral CSI changes for the postoperative outcome in temporal lobe epilepsy.

PURPOSE: In a prospective study, we evaluated the significance of preoperative bilateral chemical shift spectroscopy imaging (CSI) changes for the prognosis of postoperative seizure outcome in the surgical treatment of patients with temporal lobe epilepsy (TLE). METHOD: CSI using multivoxel spectroscopy was performed. Twenty-six consecutive TLE patients scheduled for epilepsy surgery were included. To evaluate the value of the CSI with respect to postoperative seizure outcome, discriminant analysis with ipsilateral and contralateral CSI was performed. RESULTS: The discriminant analysis showed that the contralateral metabolic changes alone are able to predict seizure outcome whereby 92.3% of cases were correctly classified. Upon comparison of the two groups of seizure-free and non-seizure-free patients with respect to contralateral metabolic changes, the difference proved to be highly significant (paired t test: t = -6.3, df = 24, p < 0.001). CONCLUSION: Bilateral metabolic CSI changes have a predictive value for the postoperative outcome in patients with TLE. In patients with severe bilateral metabolic changes, poor seizure outcome is a likely result.

Adolescent↗

Nuclear magnetic resonance (NMR) imaging in diseases of the central nervous system: initial results.

Initial experiences with Nuclear Magnetic Resonance (NMR) imaging in various intracranial diseases are reported. The images were obtained with a 0.2 Tesla resistive magnet NMR-imager of SIEMENS and the influence of different imaging techniques (spin-echo and inversion recovery) with various imaging parameters (spin-echo) on the quality and the character of the images were studied. Typical clinical examples are demonstrated and first comments are made on the quantitative evaluation of T1- and T2-relaxation times.

Adult↗