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Biomedical subjects

W Huk

Publications and source records attributed to W Huk.

At least 55 records · Page 3Linked to original sources

Cerebral complications following induced hypotension.

Over an 8-year period (1977-1984), 1,802 otorhinolaryngological procedures were performed under controlled hypotension. Four patients showed symptoms of cerebral damage post-operatively. One patient had pre-operative unrecognized stenosis of the internal carotid artery, another a hypoplastic vertebral artery. In this female patient, the head had been strongly rotated to the side to expose the surgical field, and the internal jugular vein removed. She died of general ischaemic brain damage on the seventh post-operative day. In the remaining two patients, symptoms of cerebral ischaemia did not occur until the third and eleventh day, respectively, so that the causative role of hypotensive anaesthesia is uncertain. The cases described represent a cerebral morbidity of 4:1,802 (0.22%) and a mortality of 1:1,802 (0.06%). It is concluded that controlled hypotension is a safe technique if the indication is stringently applied, and any risk-bearing factors are carefully excluded.

Adult↗

Psychopathometric demonstration and quantification of mental disturbances following myelography with metrizamide and iopamidol.

Groups each consisting of ten patients underwent lumbar and cervical myelography with metrizamide and iopamidol, together with a control group of ten patients who underwent lumbar punctures only. These groups were studied with a psychopathometric test procedure in order to demonstrate and quantify mental disturbances. It was shown that in contrast to myelography with iopamidol, mild mental disturbances are common after myelography with metrizamide. The severity of the mental disturbances after myelography with metrizamide was dependent on the quantity of contrast medium which diffused into the intracranial space after myelography, suggesting a dose-related neurotoxic effect of this substance. Such a correlation was not found with iopamidol.

Adolescent↗

[Sonographic diagnosis and follow-up study of a congenital brain tumor].

In a newborn with neurologic abnormalities a congenital brain tumor was found by gray scale sonography. By its dense structures the tumor could easily be separated from the surrounding healthy brain. Development of hydrocephalus and cystic degeneration of both hemispheres was observed by serial ultrasonography studies, which were in accordance with computerized tomography and post mortem examination.

Brain Neoplasms↗

Nuclear magnetic resonance (NMR) tomography of the central nervous system: comparison of two imaging sequences.

A brief description of a nuclear magnetic resonance (NMR) imaging system and preliminary results from its clinical evaluation in the study of various central nervous system diseases are presented. Particular attention is paid to NMR capabilities for soft tissue discrimination, topographical demarcation, and specificity of diagnosis. Two imaging sequences were used: (a) Spin echo measurements with four sets of imaging parameters revealed the different appearances of normal and pathological structures. (b) Inversion recovery images showed marked gray-white matter contrast and clear depiction of pathological lesions. Finally, a number of measurements of longitudinal (T1) and transverse (T2) relaxation times of normal and pathological tissues were carried out.

Adult↗

[Spontaneous intracerebral hematomas: occipital lobe hemorrhages].

Spontaneous intracerebral hematomas can be diagnosed immediately and localized exactly by the means of cranial computerized tomography. The occipital lobe is a relatively rare site of hypertensive hematomas which are the most frequent etiologic group. Out of 264 patients with intracerebral hematomas ion cranial computerized tomography we found the occipital lobes affected in 24 cases i.e. 9%. 116 patients with intracerebral hematomas treated in the neurologic clinic demonstrated in 15 cases (13%) occipital localization. In 7 patients bleedings were of hypertensive origin, in 4 cases etiology was unknown, in one case it originated from an arteriovenous angioma and in 3 cases congophilic (amyloid) angiopathy was the basic disease. In smaller occipital hematomas the clinical symptoms are relatively mild, mainly consisting of acute headache and hemianopsia. If the hematoma is limited to the occipital lobe the prognosis is favorable both with or without neurosurgical treatment.

Adult↗

[Remarkable clinical findings relating to the differential diagnosis of noninflammatory exophthalmos].

Communication concerning the diagnosis and treatment of noninflammatory vascular exophthalmos: (1) 12-year-old boy suffering from a 4 mm proptosis on the left eye, and a hemangioma of the left upper lid. Computerized tomography showed an orbital tumor whose dilated vessels extended into the foramen opticum. Since the patient was amblyopic the treatment was merely cosmetic, consisting in diathermic puncture of the lid hemangioma. -(2) 45-year-old woman suffering from an axial proptosis of the right eye. Computerized tomography showed a retrobulbar tumor compressing the optic nerve. Surgical removal of a cavernous hemangioma by the neurosurgeon led to restitutio ad integrum. -(3) 8-year-old boy with intermittent exophthalmus on the left. No tumor detectable in routine examinations. External carotid angiography finally revealed an arteriovenous shunt between the A. maxillaris and the V. orbitalis superior. -These three descriptions of patients suffering from exophthalmus illustrate currently available possibilities of ophthalmologic and neurosurgical collaboration for diagnosis and treatment.

Child↗

[Stenoses of the cerebral arteries in pseudoxanthoma elasticum (author's transl)].

The Grönblad-Strandberg-Syndrome (Pseudoxanthoma elasticum) is a systemic disease of the elastic tissue, typical symptoms being lesion of skin and ocular fundi. The frequently appearing vascular changes, particularly of occlusive nature, are important for the patient's prognosis. Several clinical observations had led different authors to assume cerebrovascular involvement. Our neuroradiological findings support this opinion: In this report on a 45-year-old patient with acute hemisyndrome, we demonstrated, for the first time using computerized tomography, ischemic infarcts of both cerebral hemispheres. Cerebral angiography showed bilateral stenoses of the internal carotid arteries with further irregularities of the lumen of the intracranial arteries.

Carotid Artery Diseases↗

[The computer tomographic appearances of subdural empyemas (author's transl)].

The computer tomographic appearances of subdural empyemas are described, based on 17 cases. The empyema appears underneath the calvarium as a sickle of half-moon shaped translucency. It is separated from the surface of the brain by a narrows opacity which is greatly enhanced by contrast medium. Most cases showed, in addition, a local reaction of the brain due to an encephalitis which resulted in an expansive process greater than that due to the empyema itself.

Adolescent↗

A case of bilateral temporal lobe agenesis.

A 76-year-old man with bilateral temporal lobe agenesis producing clinical features resembling the Robinson syndrome is described. The malformation was discovered during a routine CT examination after the appearance of a homonymous visual field defect. The patient was examined by (neuro) psychological testing. The findings are compared with other reported cases and discussed with regard to cerebral localisation.

Aged↗

A new targeting device for stereotaxic procedures within the CT scanner.

A new targeting device is reported which makes it possible to perform stereotaxic procedures within CT scanners under tomographic control. The zero position of the biopsy needle is the reference point for all measurements. The head of the anesthetized patient is immobilized with firm plastic cushions in a special head holder. This unit can be used for biopsies, preoperative marking of small lesions, therapeutic punctures, and placement of radioactive substances into inoperable brain tumors.

Biopsy, Needle↗

Cranial computerized tomography in children with lymphoid malignancy and seizures.

Focal and generalized seizures occurred in 4 patients with acute lymphoblastic leukemia and non-Hodgkin-lymphoma. The etiology of the neurological complications could be established by cranial computerized tomography (CT): i.e., 1. localized metastasis with calcification and 2. acute intracerebral hemorrhage during induction therapy in two patients with malignant lymphomas; 3. diffuse cerebral infiltration with blast cells and 4. cerebral atrophy in two children with acute lymphoblastic leukemia who were in relapse. Accurate diagnosis of cerebral complications in hemoblastoses is essential for appropriate therapy and CT may lead to more effective treatment in patients with lymphoid malignancy and seizures.

Adolescent↗