Search PubMed⌕ Search

Biomedical subjects

W Haase

Publications and source records attributed to W Haase.

At least 235 records · Page 13Linked to original sources
PubMed1976

[The effect of n-butanol on the metabolic status of some organs of rats and the circulation of rabbits].

Rats received n-butanol i.m. in a dose of 0.1 g/kg body weight/die during 50 days. The metabolic status of some organs was examined and compared to that of rats which in control experiments had received 0.9% NaCl-colution in an equivalent volume (double blind experiments). The tissue levels of metabolites of the adenylic acid-creatine phosphate system, of glycogen, glucose and lactate exhibited no significant differences in both the groups. In the liver the tissue level of glycogen, free creatine and total creatine was significantly elevated in rats which had received n-butanol. In concious rabbits the effect of n-butanol on circulatory parameters was investigated in double blind experiments. n-butanol was without a significant effect in a dosage of 0.008 g/kg. A dosage of 0.033 g/kg and particularly of 0.1 g/kg resulted in a transitory decrease in the heart rate and the systolic and especially diastolic blood pressure.

Animals↗
PubMed1976

[Advantages and disadvantages of deliveries after induction of labour by convenience (author's transl)].

The development of 601 deliveries after induction of labour by convenience, 92 births after induced labour following pregnancies at risk and 1829 births after spontaneous onset of labour were examined and compared. The data were recorded retrospectively and submitted to an electronic data processing. Patients with whom the labour was induced had the shortest birth times, the difference amounted on average to 2 hours. In the comparison collective with spontaneous setting in of labour a hypotonic uterus motility was found to be the most frequent pathological labour activity. Pathological pattern of heart frequency, especially late decelerations were most frequently registered with fetuses of the risk group. The frequency of the operative deliveries amounted to 13% in the case of the collective of the induced labour, 35,9% in the case of patients in the risk group, and 10% in the case of the comparison collective. Threatening fetal asphyxia and protracted extrusion period were in the case of primiparas after induced labour equally often the indication for a vaginal-operative delivery, whereas with the comparison collective, in the risk group and also with multiparas after induced labour, the threatening fetal asphyxia was primarily for the carrying out of a forceps delivery or a vacuum extraction. Concerning the birth weight and size the new-borns of the collectives examined showed no significant differences. The best Apgar-score was achieved by the new-born induced labour babies. Only 0,5% of these babies showed pronounced signs of placental dysfunction, in the risk group 9,6%, and in the comparison collective 1,6% of the babies were born with a pronounced Clifford-syndrome. Induced labour babies did not need any pediatric treatment. There were no perinatal deaths. In the case of comparison collective, long term pediatric treatment was necessary for 8 babies, 1 baby died subpartual, another one in the pediatric clinic, that means a perinatal mortality of 0,1%. In the risk group 3 babies needed pediatric treatment, 1 baby died of the consequences of a serious erythroblastosis, the perinatal mortality amounted to 1,1%. In a critical evaluation of the without exception favourable obstetrical results after induced labour, the technical, personal and organisational efforts should not be overlooked. This stands in the way of a widespread use of the process in the near future. The results hitherto permit the temporary inference that 1) psychologically positive prerequisites for the birth are created if the pregnant woman knows a firm date for the delivery, 2) the whole partus can be continuously supervised and the maternal and infantile emergencies prevented in good time and 3) through the calculability of risks during pregnancy and birth, perinatal mortality and morbidity can be reduced considerably.

Apgar Score↗
PubMed1976

[Subnormal binocular vision -- principles for the classification of microstrabismus (author's transl)].

The studies of several hundred case records, most of them carefully observed for years, show that a simple definition of microstrabismus is not sufficient. Contrary to usual opinions about correspondence problems 7% of these cases were even found to be corresponding normally. One third of the cases remained unstable in their sensory behavior. In our opinion combinations of 4 sensopathological prinicples allow a better description of the clinical findings in cases showing a more complicated state. The 4 prinicples are 1. haziness of cortical connections, 2. rivalry of more than one correspondence, 3. horror fusionis, 4. inherited amblyopia -- inborn lack of monocular capacity. Furthermore it can be demonstrated that the four prinicples match with recent findings in neurophysiology and neuroanatomy.

Adult↗
PubMed1975

[Experiences in the measurements of correspondence using dark red glass and according to image after Cüppers (author's transl)].

The measurement of correspondence using a dark red glass in front of the fixating eye and a foveal after image in the deviating eye according to Cüppers is really an efficient clinical method. In spite of the fact that we are dealing with a dissociating test this method offers these advantages: 1. The objective angle is well known at any time. 2. This method allows a sufficient discrimination in the range of 15 min. of arc. 3. There is a permanent retinal stimulation contrary to the method utilizing after-flash images.--General objections to dissociating tests, for example that given by Goldman, are only limited value, because of the fact that patients with disturbed functions must be differentiated easily from normal persons. Sources of error system mainly from inconcentrated fixation. There is a great demand for attention on the part of the patient. Using this method we have been able to show the 17 cases examined up to now a paradoxical anomaly, demonstrated by a larger subjective angle than the objective angle. Besides that we could prove that lability of correspondence, characteristic for an anomaly, and its alteration depending on which method was used. A paradoxical anomaly was also obtained with other methods such as Hering's after images alone, after image plus real object + Haidinger brushes (synoptophor). From five examples the conditions are presented under which this phenomenon was observed up to the present. The reason of paradoxical anomaly may be seen in the loss of specific ability of cortical cells to localize exactly, especially those cells which are stimulated by foveal area, so that subjective localisation becomes very inexact.

Afterimage↗
PubMed1975

[Controlled hypothermia of ischemic extremities for the prevention of tourniquet shock].

The tourniquet-shock in dogs was produced after recirculation of ischemically stressed bilateral hind limbs. 4 of 7 dogs died within 5 hours after release of the tourniquets. The cause of heart failure could be defined by hypercaliaemia, metabolic acidosis and hemoconcentration. The development of tourniquet-shock could be suppressed by hypothermic preservation of the ischemic extremities.

Acidosis↗
PubMed1975

[The pharmacokinetics of papaverine and its bioavailability from a sustained-action preparation].

The serum levels of intravenously and orally given papaverine were determined in healthy, fasting beagles. The bioavailability of the drug was assessed in the same animals following single administration of the sustained-action preparation Panergon (papaverine-hydrochloride). Based on a one-compartment model, the time of invasion, the half-life of elimination, the volume of distribution and the absorption rate of papaverine were calcualted. A comparison of the areas under the concentration curves shows the complete bioavailability of the papaverine contained in Panergon.

Administration, Oral↗