The effects of auditory masking on the anxiety level, frequency of dysfluency, and selected vocal characteristics of stutterers.
Explore the source record for details and available documents.
Acoustic Stimulation↗
Biomedical subjects
W H Moore
Publications and source records attributed to W H Moore.
Counter telescope measurements of a beam of negative pi mesons.
Explore the source record for details and available documents.
Electrons↗
The effects of 2.0 BeV protons in mice. BNL 7343 (SM-44/23).
Explore the source record for details and available documents.
Animals↗
Vibrational analysis of peptides, polypeptides, and proteins. 3. alpha-Poly(L-alanine).
Starting with a force field transferred from our earlier studies on beta-polypeptides, we have calculated the optically active normal vibration frequencies of alpha-helical poly(L-alanine) and poly(L-alanine-N-d). The 47/13 helical structure was used, and all atoms were included. Only small modifications to the force field were required, and most of these could be justified. The analysis indicates that amide II' is in Fermi resonance with one component of CH3 asymmetric bend, thus leading to a small modification of C-N and C=O stretching force constants. The agreement between calculated and observed Raman and infrared bands is quite good. This has encouraged ls to calculate the influence of small structural changes on the spectrum as a means of explaining the observed effects of temperature changes.
Alanine↗
A rapid method for the production of erythrocytes in the state "EC4" and "EC43".
The present report describes simple methods for preparing red blood cells coated with complement components. Erythrocytes coated strongly with C4 and C3 (EC43 cells) can be prepared using the standard sucrose hemolysis reaction system. Erythrocytes coated with C4 but not C3 (EC4 cells) can be prepared by a slight modification (addition of EDTA to sucrose prior to adding serum). Occasional sera (especially from black subjects) produced weak C3 coating of red blood cells in the modified sucrose hemolysis reaction. This C3 coating could be entirely abolished (without reducing C4 coating) by using Mg++ poor serum produced by dialyzing serum against Mg++ free barbital buffer. The EC43 and EC3 cells are extremely useful in analysis of anticomplement antiglobulin sera.
Binding Sites↗
A method for radioactive antiglobulin testing with 125I labeled anti-IgG.
The present report describes a method for 125I anti-IgG antiglobulin testing. The method involves the use of a labeled DEAE cellulose IgG fraction of goat anti-human IgG globulin. Leukocyte-free red blood cells were used in the test procedure. Both the labeled antiserum and the red blood cell suspensions were diluted in normal rabbit serum to prevent non-specific uptake of labeled antiserum by normal, uncoated red blood cells. The results of the study show that the method is highly reproducible and relatively easy to perform once the labeled anti-IgG is prepared. Furthermore, the use of labeled antiserum permits analysis of antiserum specificity by radioimmunoelectrophoresis. The problem of determining anti-IgG/IgG binding ratios remains the major disadvantage to using the method to determine precise amounts of human IgG coating red blood cells.
Animals↗
A rapid method for the preparation of high potency auto and alloantibody eluates.
The present report describes a modified, rapid acid-stromal method for elution of erythrocyte antibodies. With this method, potent crystal clear auto and alloantibody eluates can be produced. The simplicity of the method makes it readily adaptable to the routine serological laboratory or blood bank. In semiquantitative and quantitative studies, we have found that this method compares favorably with other antibody elution methods. With alloantibodies, the rapid acid elution method and the ether method produced the strongest eluates with the ether eluates being slightly more potent than the rapid eluated. By contrast, with autoantibodies the rapid method was clearly superior, producing much stronger IgG erythrocyte coating as judged by the 125I antiglobulin test.
Antibodies↗
Radioactive antiglobulin testing with 125I anti-C4 and anti-C3.
The report describes methods for quantitating C4 and C3 coating of red blood cells using 125I anti-C4 and anti-C3. Two methods of preparing antisera were used; one involving absorption and elution from complement coated cells, and the other employing IgG fractions of antisera prepared on DEAE cellulose. White-cell-free red blood cells were used in the test procedure. Both the labeled antisera and the test cells were diluted in cold carrier proteins, initially bovine serum albumin, but more recently normal rabbit serum. We have found that normal rabbit serum is particularly effective in reducing the high uptake of nonspecific counts on normal cells, which had previously been a major technical problem for the radioactive antiglobulin technique. These methods are highly reproducible and relatively easy to perform once the labeled antisera are prepared. Furthermore, the use of labeled antisera permits analysis of specificity by the highly sensitive technique of radioimmunoelectrophoresis. One problem with the technique is that results indicate uptake of labeled antisera, rather than amounts of coating substances. Nonetheless, the ease of performance and the reproducibility of the method, make the procedure very useful in comparative studies of uptake of C4 and C3 by red blood cells.
Antibodies↗
Neutron spectra from 35 and 46 MeV protons, 16 and 28 MeV deuterons, and 44 MeV 3He ions on thick beryllium.
The energy spectra of neutrons produced by 35 and 46 MeV protons, 16 and 28 MeV deuterons, and 44 MeV 3He ions on thick beryllium were measured at angles of 0 degrees, 15 degrees, and 45 degrees with respect to the incident beams. The spectra were measured by the time-of-flight method for neutrons from the maximum energy down to 1 MeV. Neutron dose rates obtained from the zero-degree spectra by use of available tissue kerma factors agree with TE-TE ionization chamber measurements.
Beryllium↗
Fatal hepatic necrosis after halothane anesthesia in a boy with juvenile rheumatoid arthritis: a case report.
Hepatitis from halothane is usually diagnosed by excluding other possible causes. Whether preexisting hepatic damage, which can occur in certain autoimmune disorders, contraindicates the use of halothane has yet to be proven. The case of a 14-year-old boy with early-onset juvenile rheumatoid arthritis who developed fatal hepatic necrosis 13 days after halothane anesthesia is presented.
Adolescent↗