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Biomedical subjects

W Gross

Publications and source records attributed to W Gross.

At least 163 records · Page 9Linked to original sources
PubMed1981

[How strongly does heavy work in the heat affect metabolism?].

The study covered 39 acclimatised workers of a ball-bearing forge, aged 39,03 +/- 9,95 years. Temperature of the air, relative humidity and air speed were measured immediately at work. Additionally electrocardiogram, heart rate and temperature of the skin were continuously transmitted by telemetry. Before and at the end of the shift analysis of blood pressure, heart rate, electrocardiogram, blood cells and coagulation, serum acidity and a great number of other metabolic parameters was performed. The netto calories were calculated as 3250 kcal/8 hours (= 13585 kJ/8 hours). Hematological analysis demonstrated a tendency to increase of leucocytes favouring neutrophil granulocytes. The main alterations comprised decrease of actual pH, base excess and standard bicarbonate. Furthermore serum lactate and triglycerides increased, creatinine attained the upper limit of the normal range, mineralogram remained unchanged by drinking ad libitum. The so called "liver enzymes" remained stable. As to circulatory parameters systolic blood pressure slightly declined whilst heart rate increased.

Acid-Base Equilibrium↗
PubMed1981

[Urodynamic investigations. Volume/flow and pressure/flow relationship in children (author's transl)].

Subject of the report are urodynamic investigations in 122 children with a normal urinary tract and in 168 children with disturbances of the subvesical outflow. The children were divided into four groups corresponding to age and sex. Measuring methods were uroflowmetry and cystometry. The latter was performed with small urethral plastic catheters 1,5 mm in diameter. In comparison with the investigations without catheter our measured values show a revoked or distinctly decreased dependence of the maximal urinary flow on the micturition volume. This behaviour can be explained by an approximately maximal widening of the subvesical outflow tract due to the obstructive effect of the catheter. The pressure/flow relations confirm this behaviour. They correspond to those of a rigid tube with individual constant diameter. This condition permits a good comparison between the measured values and an accurate separation between normal and pathologic cases. Normal ranges of the pressure/flow relations at the moment of maximal flow were calculated and presented by diagrams. Pathologic micturitions can be differentiated and classified by such diagrams. Among the various urodynamic methods the uroflowmetry has a good diagnostic value in boys. With the urethra resistance relation PQmax/Qmax2 a subvesical obstruction may be recognized in both sexes. A better assessment of the functional obstructive effect with regard to compensation and decompensation is only possible with the demonstrated pressure/flow diagrams.

Adolescent↗
PubMed1981

[Urine stream pressure and urethral energy loss].

In the present paper is reported on the estimation of several physical parameters of the urinary stream leaving the urethra in boys. Normal values which we determined in 33 boys could be compared with the measuring values in patients with subvesical disturbances of the passage. Proximal stenoses are characterized by a low residual energy of the urinary stream. In distal stenoses it is normal to increased. The clinical importance may result from the possibility of the diagnosis of disturbances in which quickly is to be reckoned with the development of secondary changes of the upper urinary tract with the help of a non-invasive method. The calculation of the urethral loss of energy allows further informations. It demands a suprapubic puncture of the urinary bladder for measuring the pressure.

Adolescent↗
PubMed1980

[Manometric reading of rectal pressure profiles (author's transl)].

A catheter with two side holes is inserted into the rectum and perfused by a rate of 3,1 ml/min. When drawn back (0,7 mm/sec) the recto-anal pressure is recorded. In this way normal readings of the pressure profile are established in different age groups of children and compared with reading recorded by the open-tip-method.

Adolescent↗
PubMed1979

[Hemorrhagic diathesis in patients with malignant neoplasms (author's transl)].

Clotting analysis in 30 patients with bleeding complications in malignant hematological diseases revealed the following troubles: The global tests, Quick's index and partial thromboplastin time markedly differed from normal. Activity of clotting factors revealed hypo- or hyperfibrinogenemia, disturbances of the prothrombin complex (factors II, VII, IX and X), decrease of factors V, VIII, XII. Factor XI (= PTA) was not diminished in any case. Regarding the fibrin-stabilizing factor (factor XIII), its activity was significantly decreased in 30 patients with solid tumors and in 30 patients with hemoblastoses. Faulty clotting balance was characterized by hyperfibrinolysis or disseminated intravascular coagulation (DIC) accompanied by reactive hyperfibrinolysis. About one quarter of the patients with malignant disturbances of the hematopoetic system demonstrated (mostly amegacaryocyte) thrombocytopenia. Finally, treatment of bleeding complications in malignant neoplastic diseases is pointed out.

Blood Coagulation Tests↗
PubMed1979

[Effects of propranolol and metoprolol on beta-adrenergic metabolic responses (author's transl)].

In ten healthy volunteers infusion of 7 micrograms/kg orciprenaline produced typical changes in carbohydrate and fat metabolism due to beta-adrenergic stimulation. Pretreatment with intravenously administered propranolol or metoprolol significantly inhibited orciprenaline-induced changes in systolic blood pressure, heart rate and plasma FFA, potassium, glucose and glycerol levels. Propranolol (0.1 mg/kg) seemed to be more effective than metoprolol (0.2 mg/kg) even in inhibiting predominantly beta 1-adrenergic responses.

Adult↗
PubMed1979

Metabolic changes after application of kallikrein in an ergometrical test.

Kallikrein given in a dose of 3 times 200 KE daily over 7 days caused under our test conditions an increase of ATP in blood and a decrease of lactate and especially of pyruvate. Glucose showed under this condition a higher utilization with a lowering of glucose in blood and an increase of the RQ. The acid-base metabolism follows these tendencies. In other experiments we did not find such effects, so the results must be specific to kallikrein.

Adenosine Triphosphate↗
PubMed1979

Long-term studies on therapy and tolerance of ketoprofen.

The therapeutic value of non-steroid anti-inflammatory agents for therapy of rheumatoid arthritis is discussed and a long-term study is described which was carried out for up to 12 monts on tolerance of ketoprofen compared with indomethacin. Objective laboratory data were used as criteria for possible influence on organ function. No abnormalities in renal and liver function were observed.

Arthritis↗
PubMed1979

[Urodynamic miction studies--physiological aspects].

In this work, definition and interpretation of different functional parameters, which were obtained through urodynamic investigations, are given. Normal patterns in child age are presented. They were the results of personal studies in patients with normal urinary tract. The pressure curve must be seen as an entity. The so-called after contraction is no detrusor contraction. But possibly it is the result of a determined lapse of contracting and relaxing occurrences in the different parts of the bladder and its outlet at the end of micturition.

Adolescent↗