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Biomedical subjects

W Borkowski

Publications and source records attributed to W Borkowski.

At least 55 records · Page 3Linked to original sources

Neutrophil alkaline phosphatase activity in the early puerperium.

Neutrophil alkaline phosphatase studied cytochemically according to Kaplow's method in 20 healthy women aged 20 to 38 years, shows statistically significant, although transient, increase on the second day after physiological delivery and returns to initial values after several days. The above increase is unrelated to the increased enzyme activity observed in the terminal months of pregnancy in a majority of healthy women. It is associated with an increase in neutrophilic granulocytosis in the puerperial period.

Adult↗

[Evaluation of the possibility of using the National Cancer Registry for survival analysis of children and youth with selected malignancies--leukemias and lymphomas during 1990-1995 in Poland].

There are about 1400 new cases of cancer and almost 600 deaths from cancer a year in children and youth aged between 0-19 in Poland. Leukaemias and lymphomas comprise 37.8% of the total number of cases and 43.3% of the total number of deaths from cancer. The National Cancer Registry is the unique data source of the incidence of cancer as well as further health information in particular the fact of death. In this research, pioneer attempt of using Registry data to conduct survival analysis in children and youth with leukaemias and lymphomas has been undertaken. Cox regression and Kaplan-Meier survival curves methods were used. Organizational and clinical conclusions have been formulated. Organizational conclusions concern mainly the principles of conducting the Registry namely introducing of International Classification of Diseases for Oncology (ICD-O) and extending the period of observation from 2 to 5 years. The leading clinical conclusions are: lack of improvement in prognosis in the 6 years period from 1990 to 1995 and crucial importance of early diagnosis of oncological disease for survival time. Further clinical conclusions concerning the impact of treatment cannot be made on the basis of the Registry data.

Adolescent↗

[Evaluation of the possible use of the National Cancer Registry for survival analysis of children and youth with selected malignant neoplasms--tumors in 1990-1995 in Poland].

This paper is the continuation of previous research described in the article "Evaluation of the possibility of using the National Cancer Registry in survival analysis of children and youth with selected malignancies-leukaemias and lymphomas in 1990-1995 year in Poland" on the basis of the National Cancer Registry data concerning tumours. Tumours comprise 62.0% of total number of cases and 56.6% of total number of deaths from cancer in children and youth. Modern methods of statistical analysis such as Cox regression and Kaplan-Meier survival curves method have been used. The conclusion formulated in the previous paper is still valid. Despite the fact that the Registry is not designed for survival analysis, they are possible and are the basis of many important findings. The crucial factor for the value of the Register in the time of advanced statistical analysis and computer methods is organisation of the Registry and data quality. Organizational and clinical conclusions have been formulated. Organizational conclusions concern mainly the principles of conducting the Registry namely introducing of International Classification of Diseases for Oncology (ICD-O) and extending it from 2 to 5 years the period of observation. The leading clinical conclusions are: lack of improvement in prognosis in the 6 years period 1990-1995 and crucial importance of early diagnosis of oncological disease for survival time. Further clinical conclusions concerning the impact of treatment cannot be stated on the basis of the Registry data.

Adolescent↗

[Hansa-East Project open architecture for hospital information systems--preliminary report].

Results of implementation of middleware based hospital information system in the National Research Institute of Mother and Child in Warsaw are presented. This was objective of the international information technology (IT) Hansa-East Project dedicated to promotion of UE standards CEN/TC251 ENV 12967-1 for open architecture of hospital information systems. Middleware DHE of the Italian company GESI was used. In the paper, the methodology of middleware based hospital information system is presented, as well as preliminary evaluation.

Computer Systems↗