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Biomedical subjects

W Borkowski

Publications and source records attributed to W Borkowski.

At least 19 recordsLinked to original sources

Society of self: the emergence of collective properties in self-structure.

Using cellular automata, the authors show how mutual influences among elements of self-relevant information give rise to dynamism, differentiation, and global evaluation in self-concept. The model assumes a press for integration that promotes internally generated dynamics and enables the self-structure to operate as a self-organizing dynamical system. When this press is set at high values, the self can resist inconsistent information and reestablish equilibrium after being perturbed by such information. A weak press for integration, on the other hand, impairs self-organization tendencies, making the system vulnerable to external information. Paradoxically, external information of a random nature may enhance the emergence of a stable self-structure in an initially disordered system. The simulation results suggest that important global properties of the self reflect the operation of integration processes that are generic in complex systems.

Humans↗

[Development of the normal infantile hip joints assessed by MRI].

The paper provides an overview of the time of appearance of the secondary ossification centers and closure of the growth plates of the acetabulum and proximal epiphysis of the femur: the triradiate cartilage, the acetabular roof growth cartilage, the subcapital growth cartilage, the growth cartilage of the major trochanter, the growth cartilage of the minor trochanter. The study is based upon 62 MRI scans of healthy hips in 45 patients aged 3-21. The examined hips showed no pathologic traits--neither in the MRI scan nor in X-ray investigation. In Spin Echo and Turbo Spin Echo sequential imaging all obtained slices were used, on GRADIENT ECHO: FISP 3D, FLASH 2D, and FLASH 3D FAT SAT only chosen slices were included in the study. This way the following results were obtained: the ossification center of the major trochanter appears at the age of 3 in girls and at the age of 6 in boys, while the ossification center of the minor trochanter appears at the age of 6 in both sexes. The times of complete ossification of following growth cartilages were observed: for the triradiate cartilage ossification was observed at age 12-15 in girls and 15-16 in boys; for the cartilage of the acetabular roof ossification was noted at age 12-15 in girls and 15-18 in boys; ossification in the subcapital growth cartilage occurred at age 15-17 in girls and 16-18 in boys; the major trochanter growth cartilage ossifies at age 15-16 in girls and 16-18 in boys; for the minor trochanter ossification of the growth cartilage occurs at age 14-16 in girls and at age 16-18 in boys. The secondary ossification center of the pubic bone appears at age 9-11 in girls and 13-16 in boys and the secondary ossification center of the acetabular roof appears at age 13-17 in girls and boys. This study expand our knowledge on the development of the hip joint and facilitate the assessment of hip pathology.

Adolescent↗

[An analysis of the selected parameters of the normal hip joint during growth in magnetic resonance imaging].

Dynamics of the selected parameters of the normal hip joint during growth has been presented. Fifty-three normal hips in 40 individuals aged 3-17 years were assessed with Magneton Impact MRI. The angles and indices were found on T1 coronal images in Spin Echo or Turbo Spin Echo sequence. Acetabular roof angle of Hilgenreiner, acetabular inclination angle of Sharp, Wiberg angle and Heyman-Herndon index were calculated with both bony and cartilaginous elements regarded. Parameters based on cartilaginous parts of the joint did not change during normal growth, but they do change if calculated with the use of bony landmarks reaching Acartilaginous values by the age of 14-15. The results suggest, that during growth gradual ossification of cartilaginous elements takes place but the proportions remain unchanged. The investigation determines the age of enhanced ossification and the age of its termination.

Adolescent↗

[Possibility of stereometric evaluation of child's hip structures by MRI].

A series of magnetic resonance imaging (MRI) examinations of 188 pathologic and normal hip joints has been reviewed to evaluate usefulness of this method for 3-D imaging of this joint. The age of patients ranged from 3 years to 22 years. MRI was done for diagnosis, pre-operative planning or post-operative assessment. Fifty-four hips were normal. Normal hip, dysplastic and the one after septic arthritis have been delineated. All MRI examinations were done with Magnetic Impact. Spin Echo, Turbo Spin Echo and FLASH 3D FAT SAT techniques were employed, all three planes included. All hip joint elements were separately described, the difference between the immature and adult hip were presented. Objective parameters were introduced. MRI proved extremely useful for diagnostics, surgery planning and follow-up of immature hip joint.

Adolescent↗

[Changes in the subcapital growth plate due to avascular necrosis after treatment for congenital hip dislocation in radiologic, tomographic and magnetic resonance examinations].

The aim of this investigation was to compare magnetic resonance imaging and radiography in detecting subcapital growth plate changes due to avascular necrosis after treatment for congenital dislocation of the hip. MRI was done in 16 patients (21 hips) aged 8-12 (mean 10 years), treated because of CDH. Radiographs were also done in all cases. Comparison between these two imaging modalities revealed superiority of MRI in both imaging of normal subcapital physis and imaging of its disorders.

Child↗

[Evoked response audiometry in newborn infants examined earlier by fetal audiometry].

The aim of this study was to investigate the influence of acoustic stimulus on behavioural heart responses of fetuses near term (38 to 42 weeks of gestational age) and comparison assessment of FHR to Auditory Brain Stem Responses (ABR) in the same babies after their birth. The study group consisted of 30 babies with pathological pregnancies and control group of 30 neonates of physiological pregnancies. Our results indicated, that the pattern of FHR accelerations after application of acoustic stimulus was significantly altered and depended on of the kind of pregnancy. Duration and amplitude of FHR obtained in the patients with complicated pregnancy were significantly smaller in comparison to the pattern observed in normal patients (142 msec to 249 msec, and 36 to 22 as well). Comparing the results obtained in FA (Fetal Audiometry) and ABR (Auditory Brain Stem Responses) we can say, that prolonged latency between a stimulus and accelerations is also combined with the prolonged latency of consecutive waves in ABR. Shortened duration of accelerations and its decreased amplitude could respond to the diminished amplitude in ABR recordings.

Audiometry, Evoked Response↗

[Auditory brainstem responses in full-term infants and pre-term neonates].

Auditory Brainstem Responses (ABR) and behavioural threshold were studied in 52 infants born between 28-41 weeks of gestational age (GA), which have been between 33-42 weeks of postconceptional age (PCA) (Gestational age + postnatal age). Peak latencies of wave V and interpeak latency I-V were measured as a function of maturational changes and stimulus intensities. Behavioural audiometric threshold to pure tone were determined through behavioural observation of auditory-palpebral reflex. In the group of full-term infants threshold responses for clicks lay between 32.5 to 35.1 dB. In the group of pre-term neonates the threshold lay between 37.6 do 40 dB. Behavioural audiometry disclosed that full-term infants responded to pure tone stimuli with mean threshold of 86 dB, while the pre-term infants would respond to pure stimuli at 91 dB. The latency of wave V responses decreases progressively from a mean of 7.84 ms at 33-35 weeks of PCA, to 6.57 ms at 40-41 weeks of PCA. The ABR shows a remarkable variability in wave V latency with relatively stable interpeak latency I-V with decreases stimulus intensities.

Evoked Potentials, Auditory, Brain Stem↗

MVPP chemotherapy combined with radiotherapy in the treatment of Hodgkin's disease in children: long-term results.

Between 1969 and 1975, 34 children aged 16 years and under, with Hodgkin's disease (HD) were treated and followed-up at our department. All patients received a combination of MVPP and radiotherapy. Four children died, three from uncontrolled lymphocyte depletion Hodgkin's disease and one from encephalopathy. Thirty children are disease-free, with the mean survival of 109.8 months.

Adolescent↗