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Biomedical subjects

W Adolph

Publications and source records attributed to W Adolph.

29 records · Page 2Linked to original sources
PubMed1977

[The course of asymptomatic diabetes under varying preventive therapy--concluding report of a 5-year prospective study].

During a prospective study the course of asymptomatic diabetes in different preventive treatment (diet, additionally tolbutamide, carbutamide or buformin) was observed concerning the frequency of manifestation and the behaviour of the oral glucose tolerance. Among the 100 protodiabetics after 5 years 38 clinical manifestations could be established, which finally nearly equally were distributed to all 4 groups of treatment. Only under the influence of buformin an effect preventing manifestation limited to 2 years appeared. Patients with persisting full or partial remissions continuously and more decreased in weight than cases of manifestation. Furthermore, the course was determined by the initially existing degree of hyperglycaemia as well as by the improvement of the glucose tolerance achieved in the first year. On account of the results of the examinations and the existing literature a preventive use of oral antidiabetics cannot be recommended.

Buformin↗
PubMed1977

[Casuistic contribution to the clinical picture of idiopathic hypertrophic osteoarthropathy].

On the basis of a casuistic contribution is referred to the rare, hitherto not clarified clinical picture of the idiopathic hypertrophic osteoarthropathy (pachydermo-periostosis, Touraine-Solente-Golé syndrome). In pronounced cases the diagnosis can easily be made, when pachydermia, drumstick-fingers with watch-glass nails and hyperostotic changes of the skeleton are present. Differential-diagnostic difficulties concerning the osteoarthropathie hypertrophiante pneumonique (P. Marie-Bamberger) are the result as in the present case in abortive forms of the syndrome.

Adult↗
PubMed1976

[Comparative analysis of electrocardiographic findings in diabetics and metabolically healthy persons].

The electrocardiograms of 447 diabetics and of the same number of non-diabetic test persons who were coordinated as biostatic twins, taking into consideration age, sex, and weight, were evaluated according to the Minnesota-code and compared. The cardiac endangering of the diabetics was most clearly expressed in the larger frequency of infarctions and the chronic-ischaemic heart disease which can be proved in all age groups. Diabetic males with short duration of diabetes showed the highest frequency of infarctions. The frequency of coronaropathy which is not increased in most age groups in the long-term diabetics compared with the control persons characterizes them as a positive selection of diabetics with an apparantly primarily low atherogenic potency. Hypertonus and/or adiposity were concomitant with a nearly doubled frequency of the ischaemic heart disease. The breadth of the P-wave as a possible reference to angiopathic changes in the region of the atrium was significantly larger in the diabetics in all age groups than in the control group.

Adult↗
PubMed1976

[Long-term diabetes--a special form of diabetes].

Two hundred and eight long-term diabetics from the diabetic population of one district were examined thoroughly by physicians of the several special branches and compared with a control group consisting of biostatic twins with a healthy metabolism. Case control was performed for 5 years. The frequent absence of pathological findings in the coronary, peripheric and cerebral regions as well as a significantly high percentage of standard weight and underweight were found to be characteristic signs in that patients who survived their diabetes for several tens of years. Five years after the first registration, 68 long-term diabetics and 23 subjects of the control group had been died. However, the excess mortality does not surpass the mortality of subjects diseased for a short period. Besides the age and the duration of the manifestation, the survival rate was found to be dependent on the degree of the micro- and macroangiopathies, hypertension and over-weight. On the other hand, the duration of the diabetes and the metabolic condition did not exert any perceptible influence.

Age Factors↗
PubMed1975

[Electrocardiographic findings in a selection-free number of cases of long-term diabetic patients].

When the conventional ECG after resting was used for establishing frequency and degree of severity of the ischaemic heart disease the stronger cardiac endangering of the longterm diabetic could be ascertained only from residues of an infarction (pathologic Q- and QS-types). With regard to all electrocardiographic criteria of the ischaemic heart disease according to the WHO-definition concerning the coronary risk a dependence on age, over-weight and increase of blood pressure was found without essential differences between the two groups. According to data in literature ischaemic reactions in diabetics are significantly more frequently to be expected only by inclusion of the electrocardiogram after work. Among the group of diabetics the frequency of the ischaemic heart disease increased with the duration of the disease. In contrast to retinopathy there was no dependence on the quality of the metabolic condition.

Adult↗
PubMed1975

[Studies of nephropathies in 168 diabetic patients with over 20-year onset of the disease].

Within a clinical epidemiological investigation 168 diabetics were examined multidisciplinarily who survived the beginning of their disease by at least 20 years. The qualitative proof of protein in the urine was regarded as criterion for the presence of a diabetic nephropathy. 29% of the long-term diabetics showed a proteinuria. In a control group of probands with healthy metabolism, however, only 2.5% proteinurias were found. Statistically ascertained correlations were the results in cases of proteinuria and retinopathy (microangio-pathy). Particularly close were the relations of proteinuria to arteriolosclerosis (macroangiopathy). There were no relations between the proof of a proteinuria and the quality of the control of the carbohydrate metabolism which was pursued during decades.

Adult↗
PubMed1975

[Reproducible and congruent radiographs for the study of bone structure].

Radiograms that are reproducible and are as identical as possible are an absolute prerequisite for objective early diagnosis of the smallest changes in the bone structure. Changes that are no longer visible to the naked eye, are recorded by photometry and can be represented objectively by computerized evaluation. It is the object of this study to develop a method for taking roentgenograms with films generally used in the dental office, which allows to always the area always to be radiographed reproducibly. The x-ray machine is described and tested on four patients. The radiograms are photometrically scanned and entered into a computer in order to check the location of the radiograph. The results show that with our method it is possible to take identical radiograms at different times.

Bone Development↗