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Biomedical subjects

W A Fuchs

Publications and source records attributed to W A Fuchs.

At least 37 records · Page 2Linked to original sources
PubMed1990

Diffuse idiopathic skeletal hyperostosis (DISH) of the shoulder: a cause of shoulder pain?

Shoulder pain is a common complaint and shoulder hyperostosis a frequent radiological condition. However, little is known about the association between the clinical and radiological findings. To evaluate the clinical relevance of shoulder hyperostosis we performed a controlled, blind study of 99 hospitalized probands with and without thoracospinal hyperostosis on lateral chest X-rays. The study included grading of the shoulder hyperostosis on the basis of three bilateral standard radiographs, assessing shoulder pain in a standardized way by an interviewer and recording extraskeletal causes of shoulder pain. The prevalence of shoulder hyperostosis was doubled in probands with thoracospinal hyperostosis compared to controls (chi 2 = 5.90, P less than 0.025, n = 99). Shoulder hyperostosis, irrespective of thoracospinal hyperostosis, predisposed to shoulder pain (40% versus 18%, chi 2 = 4.06, P less than 0.05, n = 74). Shoulder hyperostosis in combination with thoracospinal hyperostosis (shoulder DISH) predisposed to shoulder pain to an even greater extent (46% versus 12%, chi 2 = 6.64, P less than 0.01, n = 47). We conclude that shoulder hyperostosis is a radiological finding of potential clinical relevance.

Arthrography↗
PubMed1989

Diffuse idiopathic skeletal hyperostosis (DISH) of the spine: a cause of back pain? A controlled study.

This is the first controlled study of the frequency of back pain in a European caucasian population with diffuse idiopathic skeletal hyperostosis (DISH). Elderly patients admitted to hospital for reasons other than back pain were assessed for the presence of spinal DISH using the routine lateral chest radiograph films. A total of 106 probands (82 males, 24 females) with a mean age of 70 years fulfilled the criteria for DISH as defined previously. One hundred and seventy-eight patients (117 males, 61 females) not meeting these criteria were used as controls. The prevalence of back pain was assessed by a blinded interviewer using a structured questionnaire. Our primary hypothesis was that spinal DISH positive probands had not had back pain more often than controls. This controlled study showed no statistically significant difference in pain frequency between spinal DISH positive probands and controls at any spinal level. We conclude that back pain does not occur more often in radiographically defined DISH positive probands than in controls. The radiological finding of spinal DISH, as far as it does not lead to stenosis of the spinal canal or dysphagia, thus seems to be a finding without clinical relevance.

Aged↗
PubMed1989

[Modern radiologic imaging in the diagnosis of abdominal diseases. Magnetic resonance imaging and spectroscopy].

The diagnostic value of magnet resonance imaging for the diagnosis of pathological abdominal conditions has been limited sofar because of artefacts due to movement susceptibility. The current indications comprise: liver: differential diagnosis of metastases, cysts and hemangiomas, identification of small metastases, demonstration of malignant vascular invasion, evaluation of hemochromatosis; kidneys: evaluation of transplant rejection, analysis of complex cysts, demonstration of malignant tumoral invasion. The application of magnetic resonance will be greatly extended by the introduction of rapid image sequences and the application of specific contrast media.

Abdomen↗
PubMed1988

[Medical radiology--today and tomorrow].

Medical radiology comprises diagnostic radiology, nuclear medicine and radio-oncology. Digital radiography, sonography, computed tomography, magnetic resonance and percutaneous techniques mark the present development of radiodiagnosis. Current advances in nuclear medicine are emission computed tomographic techniques and biochemical radiopharmaceuticals. Computerized planning, combination therapy and particular types of ionizing radiation are the main ongoing developments in radiation oncology. Teaching and research have a decisive bearing on the future of medical radiology.

Diagnostic Imaging↗
PubMed1987

[Computerized tomography of the kidneys in hematuria].

Computed tomography demonstrates pathological alterations to the kidney and pararenal structures: it serves for identification and staging of malignant tumours, definition of cystic and inflammatory lesions and evaluation of major injuries.

Hematuria↗
PubMed1987

[Intravenous digital subtraction angiography].

Thanks to its high contrast resolution, intravenous digital subtraction angiography (IV-DSA) makes it possible to examine the arteries after injection of contrast media into a peripheral arm vein. IV-DSA is indicated in patients with clinical suspicion of arterial stenosis, occlusion, aneurysm or anomaly (ascending and descending aorta, aortic arch and its great vessels, and the renal, iliac, femoral and popliteal arteries). In many such patients, IV-DSA successfully replaces intraarterial catheter angiography. The advantages of IV-DSA (with a peripheral injection technique) as compared to conventional angiography, include its non-invasive character, a lower complication rate and less discomfort for the patient. The disadvantages of IV-DSA include poorer image quality due to lower concentration of contrast media in the vessels, reduced spatial resolution and the need for larger volumes of contrast media. The indication for conventional angiography is an inconclusive intravenous study due to motion artifacts and/or poor resolution.

Analog-Digital Conversion↗
PubMed1987

[Peripheral venous and peripheral arterial digital subtraction angiography in occlusive diseases of the lower extremity].

The possibility of employing peripheral venous and peripheral arterial digital subtraction angiography was examined in 351 patients of 65 to 95 years of age with arterial occlusive disease of the lower extremity. After peripheral venous contrast medium injection (using a Venflon needle 1.7-2.0 mm, 40 ml nonionic contrast medium, 20-30 ml NaCl, flow 15/s), conclusive assessment of vascular tone is possible in 86% of the cases. Indication for IV DSA is supplied chiefly by stenoses and occlusions situated proximally or bilaterally in the region of the distal aorta abdominalis, the iliacal, femoral and popliteal arteries. The distal adjacent segment is demonstrated well in 81 to 95 per cent of the cases up to the level of the trifurcation. Image quality is poor in 30% of the images of the lower leg, whereas no assessment is possible in 11% of the cases. IA DSA with fine needle (needle 0.8 mm, 3-5 ml contrast medium, 3-7 ml NaCl) is indicated in 8% of the patients to clarify the distal lower leg arteries, especially in preceding extensive proximal vascular occlusions. Conventional angiography can be largely replaced by combining peripheral venous and peripheral arterial DSA with fine needle technique.

Aged↗
PubMed1987

[Familial hemophagocytic lymphohistiocytosis (case report)].

This is the report of a female infant ten weeks of age, who was admitted to our hospital with hyperpyrexia, hemolytic anemia and disseminated intravascular coagulation. The further course of the disease was characterized by: continuing hemolysis resulting in severe normochromic, normocytic anemia, unrelenting disseminated intravascular coagulation, increasing hepato-splenomegaly with hyperbilirubinemia and ascites. No causative infectious organism could be identified. The infant died at the age of 14 weeks from respiratory insufficiency. Autopsy revealed massive hepato-splenomegaly, ascites and bilateral pneumonia. Histologic evaluation demonstrated lymphohistiocytic infiltrates of the periportal areas of the liver, the spleen and lymphnodes. Meninges were infiltered by macrophages with ingested erythrocytes. Differential diagnosis includes an infection with leptospira icterohemorrhagica (Weils disease) and erythrophagocytosis observed after various viral infections. Also histiocytosis X or malignant histiocytosis has to be taken into consideration. The most probable diagnosis in our patient is that of familiar hemophagocytic reticulosis although the familiarity in our patient was lacking. Intra vitam diagnosis can only be established by liver biopsy which could not be performed in our patient due to the severe coagulation disturbance.

Anemia, Hemolytic, Congenital↗
PubMed1985

[Gastroenterologic radiology--present status].

Diagnostic radiology is still of paramount importance in gastroenterology, although endoscopy has replaced radiological double contrast studies in certain instances. Sonography and computerized tomography have greatly enhanced diagnostic evaluation of the abdominal organs. Invasive techniques using radiology and endoscopy have optimized both diagnosis and therapy. Close cooperation between the various specialist groups in gastroenterology is urgently needed if optimal scientific progress is to be achieved.

Biliary Tract Diseases↗
PubMed1985

Roentgenologic assessment of initial relapse in stage I-III Hodgkin's disease.

The role of conventional radiography and CT in the assessment of initial thoracic and abdominal relapse in stage I-III Hodgkin's disease has been analysed in 43 patients. Lymph node involvement was seen in all patients, extranodal involvement in fifteen. The presence of thoracic relapse had been detected essentially by chest X-ray, but CT proved to be useful for definition of the topographic-anatomic extent of tumour manifestation. In the abdomen the presence and extent of any relapsing disease had been demonstrated mainly by CT. Additional lymphangiography was necessary in only one patient.

Abdominal Neoplasms↗