[Achievements of Czechoslovak urology with the development of Czechoslovak socialist health care].
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Biomedical subjects
Publications and source records attributed to V Zvara.
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Hypomagnesemia, hypocalcemia and hypophosphatemia after renal transplantation in an 18-year-old patient is described. Serum magnesium decreased in consequence of increased renal transplant function with high urinary magnesium excretion. At the time of serum magnesium depletion, pretransplantation hypocalcemia persisted and severe hypophosphatemia developed. Magnesium oxide treatment was followed by the increment not only in serum magnesium but also in serum calcium and phosphate to normal level. Causal relationship between magnesium deficit and impaired renal transplant tubular reabsorption of magnesium and between magnesium deficit and serum calcium and phosphate depletion in the patient is suggested.
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In 19 adult patients, with renal stones containing calcium and hypercalciuria, urinary calcium and magnesium excretion and urinary calcium/magnesium ratio was investigated before and during 4 days of treatment with sodium cellulose phosphate. Urinary magnesium excretion fell following sodium cellulose phosphate therapy in all but 1 patient investigated: in 9 patients by less than 50% and in 10 by more than 50% of the pretreatment values. In the latter group of patients urinary calcium/magnesium ratio increased significantly from the mean values ( +/- SD) 3.2 +/- 1.1 to 6.77 +/- 6.9. In 6 patients serum magnesium absorption is suggested, and routine serum and urinary magnesium analysis with the early treatment of magnesium deficiency in patients treated with sodium cellulose phosphate are recommended.
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