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Biomedical subjects

V Zeman

Publications and source records attributed to V Zeman.

At least 73 records · Page 4Linked to original sources
PubMed1979

[Roentgenological characteristic of pulmonary metastases in thyroid cancer in respect of its biological behaviour (author's transl)].

In metastases of the lung which must be considered as typical in cancer of the thyroid, it is possible to differentiate roentgenologically between fine and coarse nodules, the limit being approximately 10 mm. Metastases consisting of fine nodules are by no means to be considered as representing a fatal generalisation, whereas metastases with coarse nodules are frequently accompanied by other metastases distant from the primary tumour.

Adenocarcinoma↗
PubMed1979

[Pleural and peritoneal cytology].

3857 secretions of the serous cavities were examined in 1964 to 1976. A positive finding from a first examination occurred in 58.8%, after repeated examination in 72.1%. Falsely negative findings formed 6.2%. The diagnostic certainty of examination was 93.4%. 93.5% of all findings were controlled by a bioptic or a necroptic finding and by a clinical finding and its development. In 93.0% histological sections, too, besides spreads, could be made from the sediment. A positive finding in both techniques occurred in 59.0%, in 4.5% the spread was negative and the histological section from the sediment positive; in 8.6% it was the other way round. In 13.1% the diagnosis was thus possible by the combination of spreads with a cytohistological technique. Determination of the primary localization of a malignant tumor was possible in 2/5 of positive cases independently; in the further 1/5 it was possible on the basis of cooperation with a clinician.

Ascitic Fluid↗
PubMed1979

[Clear-cell carcinoma of the thyroid gland].

The case of a 66-year old woman is presented involving the partial transformation of follicular carcinoma with a solid somponent into clear-cell carcinoma of the thyroid gland. The carcinoma in its follicular component was seen invading the capsule, striated muscle, and vessels, and metastasizing in the form of a solitary metastasis into the ilium. Postmortem examination ruled out any other aetiology of the clear-cell carcinoma.

Adenocarcinoma↗
PubMed1979

Pulmonary metastases of thyroid carcinoma.

In a group of 840 patients with thyroid carcinoma the authors found pulmonary metastases in 123 patients, i. e. in 14.6%. In 78 pulmonary metastases were the only remote ones, in the remainder they were combined also with other remote metastates, almost always bone metastases. Cases of "pure" pulmonary metastases were found in the whole group without a proved relationship to age and histology, with a slight prdominance of men, while in patients with a combination of pulmonary and bone metastases follicular carcinoma predominates and it is found mainly in patients of more advanced age. The biological behaviour of these two groups differs completely, and this should be taken into account in the international TNM classification. When investigating the biological properties of thyroid carcinoma, we evaluated in detail in a recent publication (15) bone metastases. As all remote metastases of thyroid carcinoma are included according to the classification of WHO under the common sign M1 (9), we wanted to compare some factors in the incidence of pulmonary and bone metastases.

Adenocarcinoma↗
PubMed1979

[Anaplastic carcinoma of the thyroid gland with chondroid, osteoid, and marocellular metaplasia of the stroma, associated with Hashimoto's lymphocytic thyroiditis].

Anaplastic, mostly spindle-cellular, carcinoma of the thyroid gland was diagnosed bioptically in a 65-year-old woman. Necroptically it was found that the carcinoma was associated with Hashimoto's lymphocytic thyroiditis. In the hitherto-differentiated carcinomatous parts the papillary component prevailed and the original lymphocytic stromal infiltration was in evidence here. In the anaplastic parts isolated macrocellular elements occurred and, in some places, also chondroid and osteoid structures, especially the structures of macrocellular bone tumor character. These structures were entirely missing in the distant metastases and were, therefore, evaluated as a stromal nontumorous metaplastic process.

Aged↗
PubMed1978

Differentiated thyroid cancer following radioiodide 131I therapy of hyperthyroidism--a case report.

Differentiated (papillary) thyroid cancer was detected 17 years following radioiodide 131I treatment for toxic multinodular goiter. 21 cases of thyroid cancers with previous 131 I therapy for hyperthyroidism were summarised. This combination is rare compared to the incidence of thyroid cancers following external irradiation. This may be due to higher absorbed dose to thyroid in 131I treatment.

Adolescent↗
PubMed1978

Anaplastic transformation of medullary thyroid cancer.

The paper presents a detailed microscopic study of a case of medullary thyroid carcinoma with the loss of amyloid production and of argyrophilic cellular granules combined with the prevalence of giant multinucleated cells in a part of the primary tumor and namely in metastatic deposits. These changes are believed to give evidence of anaplastic dedifferentiation. Similar cases to that reported are reviewed with the conclusion that not only differentiated thyroid cancers but medullary thyroid cancers as well are capable of anaplastic transformation. However rare the medullary thyroid cancers are, they should be diagnosed and radically treated so as to prevent their fatal anaplastic transformation.

Aged↗