[Histological contribution to the clinical picture of so-called pyodermia fistulans sinifica as manifestation of severe acne (acne conglobata et sinifica)].
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Biomedical subjects
Publications and source records attributed to V Wienert.
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The assessment of completeness of a sympathectomy can be objectively recorded and documented by dermofluorography. This method enables measurement of increased skin perfusion which leads to an earlier appearance time and steeper initial rise in fluorescence of intravenously administered sodium fluorescein. The most significant parameters are the quotients of the average appearance time and the initial rise in fluorescence of the untreated versus treated leg. Following a successful lumbar sympathectomy, these parameters were outside 3 standard deviations of the values obtained from healthy test persons.
The goal of this study was to investigate the influence of medical compression stockings on venolymphatic drainage in phlebologically healthy test persons and patients with chronic venous insufficiency. Using this new method, the outflow of an intradermally injected sodium fluorescein solution can be densitrometrically determined over a period of 60 min. In an evaluation of the method carried out over 5 weeks with 4 test persons, the variation coefficient was 19.3%, indicating a sufficient reproducibility. Concerning the effect of below-knee stockings (ankle pressure 30 mm Hg) on venolymphatic drainage, improvements of around 200 (p < 0.0001) and 250% were recorded for 10 healthy test persons (mean age 29.0 +/- 3.1 years) and 20 patients suffering from chronic venous insufficiency (classes 4 and 5; p < 0.001), respectively. The results lead us to conclude that (i) the method presented here enables a quantification of the venolymphatic drainage and (ii) that therapy with compression stockings, for both healthy test persons and patients suffering from chronic venous insufficiency, leads to a significant improvement of venolymphatic drainage.
A new technique (spatial shift alignment [SSA]) for measuring capillary blood velocity in human capillaries in the skin is described. A capillaroscopic image is digitized by means of a frame grabber. Within the lumen of a suitable capillary limb a region of interest known as a slot is placed. At a frame frequency of 25 per second, this slot is copied in a free part of the frame grabber store along a horizontal axis. A static space-time image with light diagonal bands representing the plasma gaps in their passage through the capillary limb is obtained. By determining the gradient of the diagonal bands, a measure of the capillary blood velocity is obtained. The SSA system was validated by means of a simulated model using known fixed velocities between 0 and 1.0 mm/sec (r = 0.979, n = 24). The procedure can be employed with any image processing systems, and enables continuous monitoring of the velocity measurements. Since it is time-saving and just as accurate as the frame-to-frame method, SSA could be widely applied to the measurement of blood cell velocity in capillaroscopy.
Light-reflexion rheography is a method which can confirm or invalidate the results of clinical examination and which, in any case, makes it possible to approach the diagnosis of haemo-dynamic disorders much more precisely. The author describes this technique and gives an account of the results obtained by applying this method to the various types of superficial or deep, complicated or uncomplicated, varicose veins.
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The author reports the conclusions of a multicentre investigation lead in Germany. According to this study, varicose veins are more frequent in women than in men, either in ordinary population or in in-patients. Adults are not exclusively the only ones who suffer from varicose veins; children often suffer from them too. People suffer equally from phlebitis or post phlebitis syndromes. Moreover, heredity and obesity tend to favour this tendency. Thus, the socio-economic impact is so important that the cost of treatment, hospitalization and the social cost of sick-leave must be taken into consideration. So, it is necessary for the Authorities to prevent venous diseases and be aware of the importance of phlebology.