[Food poisoning , complicated by infectious-toxic shock and acute stomach dilatation].
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Biomedical subjects
Publications and source records attributed to V V Maleev.
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The data are presented on an outbreak of salmonellosis induced by S. enteritidis. Gastrointestinal symptoms were recorded in 97.8% of 90 patients, 2.2% of them developed a generalized form. The disease ran a moderate course in 84.5% and a severe course in 2.2% of the patients majority of whom suffered from intoxication and dehydration. The therapeutic response was achieved upon rehydration treatment with crystalloid solutions.
The authors describe the data obtained by them during many years of pathogenetic treatment of patients with acute intestinal infections. Note the main errors made during treatment and giving rise to unfavourable outcomes. Give practical recommendations for carrying out pathogenetic therapy bearing in mind the age-associated characteristics and associated diseases. Draw the clinicians' attention to infusion therapy.
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The functional activity of thrombocytes (aggregation, endo- and exocytosis) and erythrocytes (aggregation) in healthy persons given a course of interferon or reaferon treatment has been studied. The results obtained in this study indicate that these preparations produce a modulating effect on the functions of thrombocytes and erythrocytes of donors having shown abnormal functional activity of these blood cells prior to the course of treatment.
Basic epidemiological regularities of El-Tor Cholera during pandemic VII are described with differentiation of the four periods of its global spread and evaluation of the efficacy of therapeutic and preventive measures. The findings of studies into the ecology of the causative organism in the surface water basins testify to the possibility of its long-lasting existence in the saprophytic phase, which requires differentiation of the anti-cholera actions. The necessity of improvement of the global epidemiological control is substantiated.
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As many as 120 patients with food toxinfections were treated by intravenous injections of kvartasol solution and the oral solutions glucosolan and rehydron. The data obtained allow the conclusion that rehydration therapy is not only not inferior to intravenous treatment but also favours the quickest recovery of the disturbed parameters of homeostasis including most rapid elimination of intoxication. Rehydron solution should be regarded as the most effective one.
As a result of studying the clinical characteristics and paraclinical signs of intoxication in 420 patients with food toxinfections, markers of intoxication have been defined: concentration of citric acid and medium molecular metabolites in blood serum and the magnitude of the leukocytic index of intoxication.
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Interrelated alterations in metabolism were discovered in patients with acute intestinal infections of medium gravity. Alterations in homeostasis express the condition of the functional and adaptive processes that develop in the organs and systems in the course of an infectious disease. Oral rehydration therapy is an effective means of treating such category of patients.
The authors applied enterodes (a low-molecular colloid solution for enteral administration) in the treatment of 35 patients with food toxoinfections. In 25 patients, the use of enterodes had to be rejected owing to the progress of dehydration. Only 10 patients received enterodes in full. The clinical effect was attained only in one female patient with mild intoxication and with the lack of dehydration. In 9 patients, the effect turned out incomplete or was absent. The authors believe that enterodes cannot be used in the treatment of patients with food toxoinfections.
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Explore the source record for details and available documents.
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