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Biomedical subjects

V V Joshi

Publications and source records attributed to V V Joshi.

At least 109 records · Page 6Linked to original sources
PubMed1978

Clinical, hormonal and ultrastructure studies of a virilizing hepatoblastoma.

Virilizing hepatoblastoma was found to be the cause of precocious puberty in a 3 1/4-year-old boy. Both human chorionic gonadotropins and alphafetoprotein in increased amounts were detected in serum and tumor tissue. These substances disappeared from the blood after removal of the tumor. Ultrastructure studies revealed the presence of dense, membrane bound, secretory granules responsible for the hormone production.

Carcinoma, Hepatocellular↗
PubMed1977

Cystic partially differentiated nephroblastoma: a clinicopathologic entity in the spectrum of infantile renal neoplasia.

Three cases of cystic partially differentiated nephroblastoma (CPDN) are presented and ten cases from literature are reviewed. CPDN has been designated by various terms; it is a cystic encapsulated tumor occurring before 2 years of age. Cysts are lined by epithelium; septa of the cysts show a mixture of partially differentiated and undifferentiated metanephrogenic blastema. This histologic feature distinguishes CPDN from multilocular cyst of kidney. In seven cases simple nephrectomy, and in remaining cases nephrectomy with radiation and/or chemotherapy, had been the treatment. The disease-free interval ranged from 5 to 72 months, without reports of recurrence or metastasis. CPDN appears to take a benign course and simple nephrectomy seems to be the treatemtn of choice. However, in view of the possibility of recurrence as shown in rare instances by congenital mesoblastic nephroma, another less aggressive lesion in the spectrum of infantile renal neoplasia, regular follow up is recommended.

Diagnosis, Differential↗
PubMed1976

Primary causes of perinatal mortality. Autopsy study of 100 cases.

Many previous reports on perinatal mortality mix primary and secondary causes of death, exclude such important causes as necrotizing enterocolitis and intrauterine growth retardation, and do not break down causes of extrinsic perinatal hypoxia. To avoid these criticisms, a slight modification was made of the list of causes of death used by the Perinatal Mortality Committee of Quebec Province, Canada. The methodology and results of 100 consecutive autopsies are described. Respiratory distress syndrome (31%), congenital anomalies (28%), and extrinsic perinatal hypoxia (17%) were the three commonest causes. Maternal, placental, or labor and delivery problems were associated with about half the cases of extrinsic perinatal hypoxia. In one case of unexplained death, sudden infant death syndrome may be considered as a possibility.

Asphyxia Neonatorum↗