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Biomedical subjects

V V Filatov

Publications and source records attributed to V V Filatov.

28 records · Page 2Linked to original sources
PubMedDate not supplied

[Morphology and morphogenetic mechanisms of brain lesions in acute generalized peritonitis].

Pronounced alterations of brain elements (vessels, neurocytes, glial cells, neural fibers and synaptic apparatus) are observed in acute generalized peritonitis. The following morphological forms of peritoneal encephalopathy were recognized: diffuse-focal lesions, incomplete partial necroses, inflammatory changes in the form of meningitis and encephalitis. The morphological changes were provoked by some factors resultant from developing endotoxicosis and homeostatic disorders. Structural disturbances may play a leading role in polyorganic insufficiency and under certain conditions may have an independent tanatogenetic significance.

Acute Disease↗
PubMedDate not supplied

[Structure of lethal outcomes of combat trauma occurred on a battlefield during the war in the Northern Caucasus].

A clinico-anatomical analysis of lethal outcomes in combat trauma allows judging about the level of organization and quality of first aid at battlefield. The investigation showed that under conditions of modern military conflicts the wounds are grave, in many cases compound and multiple. The wounds are often located on the head, chest, abdomen and lower limbs, prevailing causes of death--lethal trauma and bleeding. The results of this study show the necessity of perfecting organization and quality of the first aid at the battle field and of providing the military with modern efficient accident preventatives.

Cause of Death↗
PubMedDate not supplied

[Study of changes in the enzyme-salt composition affecting the permeability of ocular tissues under infrasound phonophoresis].

This paper deals with the study of infrasound phonophoresis-induced changes in biochemical factors, which affect the permeability of eyeball tissues. During 10 days, the rabbit right eye was exposed to an infrasound in the changing pressure mode at 4 Hz and 173 dB for 10 minutes every day. The left eye remained control. After finishing a series of studies, the animals were slaughtered, the eyes were enucleated and prepared into individual tissues. Changes in sodium-potassium composition were investigated in the first series. By causing a reduction in the cellular content of K+, infrasound exposure was found to cause a decrease in membranous potential and activation Na-channel, as confirmed by the elevated intracellular levels of Na+. This in turn enhances ocular tissue permeability for drugs without damaging the structure of a cell membrane. Changes in the activity of the following enzymes: beta-glucosidase, cathepsin D, and hy- aluronidase. Infrasound was ascertained to enhance the activity of beta-glucosidase, which accounts for the lower levels of glucose in ocular tissues and points to the activation and acceleration of biochemical processes in the tissues. At the same time the increased concentrations of cathepsin D and hyaluronidase found in ocular tissues were responsible for a temporary reduction in the viscosity of hyaluronic acid, which promotes resolution of opacities, adhesions or scars and increased tissue permeability.

Animals↗