Biomedical subjects

V Sharma

Publications and source records attributed to V Sharma.

At least 325 records · Page 18Linked to original sources

PubMed1991

Seroprevalence of HIV antibodies, Australia antigen and VDRL reactivity in Himachal Pradesh.

3000 subjects from four high risk groups--patients attending STD clinics, hospital personnel, blood donors and foreign nationals were screened for the presence of HIV antibodies HBsAg and VDRL reactivity. No evidence of HIV infection was found in Himachiali population. However, there of the 150 foreign nationals screened were found positive for HIV antibodies. Overall HBsAg positivity and VDRL reactivity was found to be 5.53 per cent and 9.07 per cent respectively. The importance of circumspected and unswerving machinery for the surveillance of HIV antibodies in the high risk population of the state is emphasised.

Adult↗

PubMed1991

The infertile women: a study of 120 cases.

One hundred and twenty cases of infertility (84 of primary and 36 of secondary infertility) were studied. The commonest cause of infertility were tubal adhesions and blockage (35.9%). Overall conception rate was 15.83%. The present study shows that laparoscopy affords and excellent assessment of tubal patency. Findings missed clinically and on hysterosapingography were diagnosed on laparoscopy. Laparoscopy and hysterosalpingography are complementary procedures and not competitive.

Adult↗

PubMed1991

[Interstitial curietherapy in penile carcinoma. Preliminary study].

Eight patients of histologically proven penis carcinoma treated by Iridium-192 implant are reported. The tumours were T1 in 2 patients, T2 in 5 patients and T3 in 1 patient. Groin status was N0 in 4 patients and N1-2A in 4 patients (fine needle aspiration cytology was negative in the latter 4 patients). Six patients achieved complete local control with excellent cosmetic result with follow-up ranging from 6 to 24 months. One patient who had local failure was salvaged by partial penis amputation, and one patient was lost to follow-up (LTFU). None of the patients developed groin nodes.

Biopsy, Needle↗

PubMed1991

Post-epidemic serological survey for JE virus antibodies in south Arcot district (Tamil Nadu).

Following an extensive epidemic of Japanese encephalitis (JE) in 1981, a serological survey was carried out in the South Arcot district of Tamil Nadu in April 1982. Serum specimens were obtained from 10 villages with serologically proven infections and 6 villages with no reported case of encephalitis during the 1981 epidemic. The serum specimens tested for haemagglutination inhibition, complement fixing and neutralizing antibodies, showed a high prevalence of JE (49.17%), West Nile (40.78%) and dengue (18.14%) viruses with predominance of JE. The prevalence did not differ between the villages with or without Japanese encephalities. There was also no difference between the family members and neighbours.

Antibodies, Viral↗

PubMed1991

Seroprevalence of HIV infection in Himachal Pradesh.

Serum samples from 2645 individuals representing all the twelve districts of Himachal Pradesh were screened for antibodies to Human immunodeficiency virus (HIV), employing ELISA test. These were categorised into four major high risk groups, viz, patients attending STD clinics (1305), voluntary blood donors (1012), hospital staff dealing with blood and blood products (200) and foreign nationals (128). No evidence of HIV infection was found in Himachali population. Two foreign nationals were repeatedly found positive for HIV antibodies by ELISA test and these were confirmed by Western Blot technique.

Adult↗

PubMed1991

Serum cholesterol levels in carcinoma breast.

A total of 56 histologically confirmed cases of carcinoma breast were analysed in terms of serum cholesterol levels, age, religion and dietary status of the patients. Age-matched controls from the same geographical area were chosen from the relatives/attendants of patients, to rule out the possible influence of environment, socio-economic, cultural and dietary practices. The mean serum cholesterol level of patients was 193.07 mg/dl (+/- 36.39), as compared to 216.32 mg/dl (+/- 30.51) in the controls (P less than 0.001). A significant difference in the blood cholesterol levels between non-vegetarian and vegetarian patients was also observed (P less than 0.001), as also between vegetarian and non-vegetarian patients and the controls (P greater than 0.025).

Adult↗

PubMed1991

Importance of dose per fraction and estimation of an alpha/beta value for the late complications of the vocal cord.

The incidence of late complications for different sizes of dose per fraction is analysed in 208 cases with squamous cell carcinoma of the vocal cord. The series comprised 156 cases with T1N0M0 and 52 cases with T2N0M0 lesions. Radical radiotherapy was given with three different regimens having dose per fraction of 3.33 Gy, 2.5 Gy and 2.25 Gy. There were 46 cases of late radiation induced laryngeal oedema. Using this clinical data an alpha/beta value of 2.35 +/- 0.13 Gy was estimated for late complications of the vocal cord. It was found that there is strong correlation between size of dose per fraction and the risk of late complication in the vocal cord.

Carcinoma, Squamous Cell↗

PubMed1991