Properties of mouse leukemia viruses. VI. The core of Friend virus; isolation and constituents.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to V Moennig.
Explore the source record for details and available documents.
Four mouse monoclonal antibodies generated against Brucella melitensis 16M, and three generated against B. suis 1330 were analysed. An ELISA (enzyme-linked-immunosorbent assay) with whole cells as antigens was used to determine cross-reactivities with other Gram-negative bacteria. Two antibodies showed cross-reactivity with smooth Brucella strains only. Five antibodies also reacted with Yersinia enterocolitica O:9, but not with other bacteria. Two of these antibodies had significantly higher titres with A greater than M serotype Brucella strains, indicating that these epitopes are related to the antigenic A complex. The antigenic determinants recognized by the monoclonal antibodies showed varying degrees of susceptibility towards oxidation. They were shown by immunoblotting to be located on the polysaccharide moiety of the O-side chain.
Mice could be protected against Friend leukemia virus infection by innoculation with highly purified viral glycoprotein GP71 or its specific antiserum.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.