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Biomedical subjects

V Masini

Publications and source records attributed to V Masini.

At least 37 records · Page 2Linked to original sources

[Disorders of formation and conduction of the cardiac impulse in hypertrophic and congestive primary myocardiopathy].

Little information is available regarding cardiac automatism and conduction disturbances in patients affected by congestive (CCM) or hypertrophic (HCM) cardiomyopathies. For this reason 29 patients with HCM (10 cases) and CCM (19 cases) and disturbances of sinus node automaticity or AV conduction underwent an electrophysiologic study. Eight patients affected by HCM were also submitted to cardiac catheterization. Sinus node function was normal in each of the HCM patients, and impaired in 6 of the 19 CCM patients. The intra-atrial conduction was prolonged in only one CCM case. One HCM and 2 CCM patients showed an impaired intranodal AV conduction. Thirteen patients (44%) showed a prolonged HV interval (3 HCM and 10 CCM patients). No calcific deposits on the aortic valve were discovered by X ray stratigraphic examination in any of the patients. In 6 cases a progression of the conduction disturbances was observed. Ventricular pre-excitation was present in 4 patients (13%).

Adolescent↗

Ambulatory monitoring in normal children.

An Ambulatory ECG monitoring (AM) was carried out over a 24 hr. period on 90 healthy children divided into 3 age groups (lst week of life, 1 year of age and 5 years of age). There was a high number (about 50%) of unusable registrations because of detached electrodes, broken leads, and artifacts. The AM on children is characterised by: a) high values of the maximum frequencies (mean maximum absolute frequency 178 at birth, 164 at one year, 154 at 5 years); b) a great difference between the maximums and minimums; c) hourly variations related, above all, to feedings in the new-born babies and of a circadian type in the 5 years old children; d) almost constant marked sinus arrhythmias (80%); extremely rare extrasystolia (7.5 atrial, 2.5 ventricular) and always isolated; e) presence of upward (27%) and downward deflection (10%) of the J point sometimes accompanied by modifications of the T wave (22%).

Adult↗

Possible risks of general anesthesia in patients with intraventricular conduction disturbances.

In order to assess the risk of complete AV block in patients with intraventricular conduction disturbances who undergo general anesthesia, 20 patients with various conduction defects (7 LBBB, 1 RBBB and 1st degree AV block, 1 incomplete RBBB, 9 RBBB + LAH and 2 RBBB + LPH) were studied by means of His bundle recording and corrected sinus node recovery time (CSNRT) before and after the subministration of thiopental (0.2 g I.V.), succinylcholine (1 mg/kg I.V.), Fluothane (1%) and Ethrane (1.6%). Nineteen patients displayed signs of dizziness or syncope; both the sinus rate and the CSNRT, did not undergo significant variations. A slight and not significant variation of intranodal conduction during sinus rhythm was observed after Fluothane administration (AH was prolonged by 8%). A less evident negative dromotropic action of thiopental and Ethrane was only revealed by atrial pacing. No significant variations were demonstrated in His-ventricular conduction after administration of the various drugs. The maximum average increase (1.5%) of the H-V interval was observed after administration of succinylcholine. Acute AV block distal to the His bundle appeared in three patients after succinylcholine administration.

Anesthesia, General↗

Intermittent and arrhythmic "runaway" pacemaker.

An unusual case of intermittent and arrhythmic runaway pacemaker is described. The malfunction was detected during implantation, at which time it caused ventricular fibrillation in the patient in whom it was implanted. The authors wish to emphasize the necessity of accurate pacemaker testing in the factory and the operating room, and to stress the importance of manufacturing pacemakers unable to emit a high number of impulses, even in the presence of a faulty circuit component.

Arrhythmias, Cardiac↗

Dynamic electrocardiogram in normal subjects during sexual activity.

An Holter ECG has been recorded for 24 h in 10 couples that had during such time a normal sexual contact. The age varied from 20 to 37 years for women, and 25 to 49 years for men. The average of maximum, medium and minimum rate was major in women than in men. During the initial phase of sexual activity an increase of about 30 beats per minute is verified up to an average rate of 104 b.p.m. without any differences between the two sexes. During realization phase the rate increased ulteriorly. This kind of increase is major and more prolonged in women (137 X 2.8 min.) with respect to men (126 X 2.1 min). The maximum rate observed during sexual contact wasn't superior to the maximum rate observed during the day. We conclude that a normal sexual activity doesn't represent a very pronounced strain, provoking a tachycardia equal to 60-70% of maximum rate of patient and for a short period of time. This should be kept in mind when judging on sexual activity of cardiac patients.

Adult↗

Dynamic ECG in normal subjects.

A study by dynamic electrocardiography has been carried out for 24 hours on 100 healthy subjects (50 males and 50 females), of ages included between 20 and 70 years. Recording were carried out during an average working day. Average high, mean and low heart rates have been calculated in the 24 hours, at various times of the day, during mental work, physical effort, sexual activity (20 cases) and sleep. Sinus arrhythmias of various degrees (bradycardia, S-A blocks) have been observed overall in 16% of cases. Incidence was higher in younger subjects (12%) as compared with the older group (4%), and during sleep (75%) as compared to periods of wakefulness (25%). Supraventricular and ventricular arrhythmias hae occurred respectively in 20 and 21% of all subjects. Both types of arrhythmias (S.V. and V.) occurred more frequently in older subjects (34 and 32%) as compared to the younger group (10 and 5%). Supraventricular ectopic beats were more frequent during wakefulness (59.3%) rather than during sleep (40.7%); vice-versa, ventricular ectopic beats have been noticed to appear more frequently during sleep (74.5%), than during wakefulness (25.5%). Overall, arrhythmias have not been common (less than 500 ectopic beats/24 hours and less than 50 ectopic beats/hour), and only rarely they were repetitive. During our study we have observed ST changes or upward deviation, but in all cases a definite pathological significance was missing.

Adult↗

[Permanent endocardiac atrial pacing and sensing. Preliminary experience with screwing catheters].

25 patients affected by sick syndrome (SSS) and normal AV conduction (15), SSS with AV conduction defects (6) and complete AV block (3) were treated respectively by means of atrial pacing. AV sequential pacing and atrial triggered-ventricular pacing. In the cases for atrial pacing and sensing, the Medtronic mod. 6957 screwing lead has been utilized. The technique resulted very simple and safe. The average atrial threshold was 1.4 +/- .05 V. (1.95 +/- 0.75 mA). The average total impendance was 740 +/- 240 ohm and the average atrial potential 2.7 +/- 1.43 mV. Two cases of early displacement of the lead were observed (due to the operator poor familiarity with the new lead). Temporary sensing defect was observed in two patients and promptly abolished by steroid therapy. No exit block was observed. The patients have been followed for an average period of six months. All the leads are sensing and pacing correctly.

Aged↗

[Mortality and hospital complications of the myocardial infarction after dismissal from the coronary care unit (author's transl)].

259 patients affected by myocardial infarction were followed after their dismissal from the Coronary Care Unit. Monitoring rate, reached 14,3% as well as serious complications which were distributed equally during this period. Death was caused by cardiac decompensation (48.6%), serious arrhythmia (16.3%), cardiac break down (13.5%), repeated infarction (10.8%), sudden death (10.8%). In all cases the autopsy revealed serious cardiac damage and widespread coronary alteration. According to statistics, death and the onset of complications appear according to age 55 years, Peel's index 12, anterior infarction, presence of complications in the C.C.U. Important among such complications are: symptoms and clinical signs of decompensation, serious ventricular arrhythmia, advanced BAV and interventricular block. The AA. reached the conclusion for the necessity of installing areas of subintensive care for the benefit of subjects who presented serious complications during their stay in the C.C.U. (about 40% of the cases). It is foreseeable that these units will have twice as many beds as the C.C.U.

Adult↗

[Epidemiological and clinical observations on 300 cases of primary myocardiopathy].

In the period from 1968 to 1977, in the Departments of Cardiology of the S. Camillo Hospital, a study has been made about 200 cases of Congestive Cardiomyopathy (MPC) and 100 about hypertrophic obstructive (MP0). Congestive cardiomyopathies constitute 1.5% of hospitalizations with a constant trend in the long run. In comparing these two forms, Authors have noticed some differences in the symptomatology of clinical and instrumental signs: 1) in case of MPO prevail angina, syncope, ejection systolic murmur, left ventricular overload in the ECG; 2) in case of MPC they find more frequently heart failure, embolism, diastolic gallop, cardiomegaly, A/V and intraventricular conduction disturbs. The AA. conclude, in accordance with Goodwin's classification, that there is not an uniformity of these two kinds of cardiomyopathies.

Adolescent↗