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V M Getsova

Publications and source records attributed to V M Getsova.

39 records · Page 3Linked to original sources

[Changes in the monoamine content of the brain influence the reaction of emotional resonance].

Influence of 5-hydroxytryptophan (5HTP) and disulfiram on a reaction of emotional resonance (RER) was studied in two groups of female rats: I--with good and II--with poor elaboration of RER and, correspondingly, with the minimal and the maximal time of stay in the dark compartment. One week after 5HTP injection good elaboration of RER in animals of the I group was substituted for poor. In the II group of animals RER was unchanged. Injection of disulfiram increased the stay in the dark compartment in the I group and decreased it in the II group. At the same time dopamine content in the midbrain and medulla increased. The results confirm the hypothesis on participation of monoamines and their different contribution in RER realization in different groups of animals.

5-Hydroxytryptophan↗

[The consolidation and reproduction of a state of haloperidol-induced catalepsy].

Catalepsy induced by a single intraperitoneal injection of haloperidol (2.5 mg/kg) was consolidated and without additional influences and retained within 2 week (being tested on the 2nd, 7th, and 14th days after injection). Enhancement of catalepsy retrieval was observed during testing of the same animals on the 14th day as compared with the 7th day. Maximal catalepsy expression was reached after 2 hours of testing procedure which points to the existence of the mechanism of autoenhancement of retrieval which is probably underlain by the automodulation of the long-lasting modulatory DA receptors. The retrieval of catalepsy is suggested to be induced by a situational conditioned stimulus, since on the 2nd, 7th and 14th days it may be reproduced without repeated haloperidol injection only in the testing box.

Animals↗