Biomedical subjects
V L Rege
Publications and source records attributed to V L Rege.
Osteomyelitis presenting as genital sore: a case report.
A female attending the skin outpatient department presented with a genital sore which was treated as chancroid. On further investigation it proved to be the opening of a sinus secondary to chronic osteomyelitis of the pubic symphysis.
Tinea capitis due to Trichophyton schoenleinii.
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Dapsone haemolysis in leprosy. A preliminary report.
Fifty one patients with leprosy from the Urban Leprosy Centre, attached to the Department of Dermatology and Venereology, Goa Medical College on treatment with Dapsone were studied from the point of view of development of haemolysis related to the drug. The findings are described and discussed. Anaemia developed in 60.7 percent of the patients during the course of treatment. It was mild and well compensated. The haemolytic effect of dapsone was related to the dose and duration of the treatment, being more manifested in doses above 50 mg daily.
Treatment of psoriasis: trioxalen and sunlight.
Eighteen psoriasis patients were treated alternately with 40 mg of trioxalen and sunlight on the right side and sunlight only on the left side. Improvement was apparent faster on the psoralen-exposed side.
Dystrophic epidermolysis bullosa. Interesting gastro-intestinal manifestations.
Involvement of the large intestine in a long standing case of dystrophic epidermolysis bullosa was characterized by recurrent episodes of diarrhoea synchronizing with exacerbation of the skin lesions. The radiological investigations revealed two narrow segments, one each in the descending and transverse colon, with ulcer craters in the lower part of the former. The haustra from the distal half of the transverse colon to the sigmoid colon were lost.
Pattern of reactions in leprosy: a clinical appraisal.
The term 'reactions' is applied in the present text, to describe the acute episodes, recognized with the different types of leprosy. The incidence of reactions was found to be 9.7% of 1053 cases examined. They were seen in all types of leprosy, but their frequency and severity was marked in lepromatous and borderline cases, and in majority of them, the age ranged from 20-40 years. The precipitating factor(s) could not be established in many; in some dapsone was incriminated, followed by bacterial infection and malnutrition. The exacerbations of the existing lesion(s) either alone or in combination with new lesions (E.N.L.) and E.N.L. lesions alone, were the presenting clinical features. The constitutional symptoms were observed largely in the types other than the tuberculoid. Foot drop and contractures of the fingers were the common sequels of the reactions. An attempt has been made to explain their mechanisms in the light of the recent literature.
Clinical pattern of vitiligo amongst Indians.
Vitiligo incidence in the series was 14 per thousand. The affliction of the younger subjects was frequent, the mean value of age at onset being 24.25 years. Both the sexes were affected and there was no significant difference between the two. The duration of the disease had wide variations, majority reporting in the course of one year. The emotional undertones and the ocurrence of the disease amongst family links were observed as provocating factors in some cases. Ivory white macules associated sometimes with erythematous tinge, leucotrichiae and islets of pigmentation were classic. The lower extremities were frequently involved, followed by face and other parts of the body. The disease was largely progressive, though in a few it was stationary. Vitiligo vulgaris was its commonest variant, followed by areata, zosteriformis, mucosae and acrofacialis. The associations namely diabetes mellitus, liver diseases and others were recorded. The occurrence of myasthenia gravis and trigeminal neuralgia in vitiligo was interesting. Its association on the basis of autoimmunity is brought out. The importance of the clinical parameters in anticipating the prognosis after psoralen therapy are discussed.
Epidemiological and clinical pattern of leprosy in Goa.
A review of 1,053 patients of leprosy revealed its prevalence in the hospital population as 2.4 per thousand. The commonly affected age group was 20-39 in both sexes; males predominating females in 1.8 : 1. The sequence of frequency of clinical types of leprosy was tuberculoid, borderline, neuritic and lepromatous. Mostly the patients report in the course of 2 years of awareness of the disease. The clinical features were classical and type specific.
Epidemiological and clinical patterns of genital lesions.
A 5-year study of 668 patients with genital lesions revealed that teenagers and those in the age group of 20 to 40 are most vunerable. The poor, the uneducated and unmarried persons are at high risk. Chancroid and syphilis are the majority of cases. Inguinal bubo, herpes pregenitalis, condylomata acuminata, erosive balanitis and traumatic ulcers were seen less frequently. Most of the genital lesions had the classic clinical features. The findings of this study suggest that the pattern of genital lesions is showing borderline changes.
An interrogative study of pattern of urticaria in children.
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Photochemotherapy of psoriasis with 4,5',8-trimethylpsoralen.
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Malignant syphilis and hepatitis. Case report.
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Chronic plasma cell balanitis of Zoon. Report of two cases.
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Herpes gestationis and repeated abortions.
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An interrogative study of 158 urticaria patients.
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Dystrophic epidermolysis bullosa in a family. Response to vitamin E (tocopherol).
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Serological (S. T. S.) survey in a hospital population. A preliminary note.
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