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Biomedical subjects

V K Ryzhkov

Publications and source records attributed to V K Ryzhkov.

At least 19 recordsLinked to original sources

Arterioportal fistulas (APF) in liver tumors: prognosis in relation to treatment.

Prognosis of 16 patients with hepatic tumors and angiographically proven arterioportal fistulas was analysed in relation to treatment. Six patients received only conservative therapy; they all died of variceal bleeding in the course of two months after angiography. Hepatic resection was performed in four patients; three of them are still alive 13-52 months later including two free of both the tumor and portal hypertension. Hepatic artery embolization was carried out in six patients. All of them died in 2-36 months after the procedure, but only two from gastroesophageal hemorrhage. It is concluded that prognosis of arterioportal fistulae in liver neoplasms is poor due to hyperkinetic portal hypertension and following variceal bleeding. Hepatic resection of both the tumor and the fistula is the treatment of choice. In unresectable cases hepatic artery embolization will decrease the risk of variceal hemorrhage.

Arteriovenous Fistula

[Embolization of the hepatic artery in the treatment of malignant tumors of the liver].

The results of therapeutic hepatic artery embolization (HAE) in 25 patients with malignant unresectable tumors of the liver are discussed. The proximal segments of the hepatic artery were occluded by metal spirals. Thrombosis of the portal vein was accepted as an absolute contraindication for HAE, and a tumor involving more than 50% of the volume of the liver and chronic hepatic insufficiency were considered relative contraindications. After the intervention signs of subjective improvement were noted in 73.9% and signs of objective improvement in 65.2% of cases. The mortality after HAE was 4.2%. The obtained results are evidence of the efficacy of proximal HAE as a method for the treatment of inoperable malignant tumors of the liver.

Adenoma, Bile Duct

[Long-term results of the embolization of the hepatic and splenic arteries in liver cirrhosis].

The authors studied the long-term results of portal hypertension correction in patients with far-advanced stages of cirrhosis of the liver. Embolization of the hepatic and/or splenic arteries was performed in 231 patients (147 males and 84 females) aged from 17 to 70 years. Sixty-seven patients are alive at present, the average duration of the follow-up period is 57.9 +/- 19.8 months. Four patients were not followed up; 160 patients died, 18 (7.8%) of them within 30 days after an endovascular manipulation. The mean survival of patients who were discharged from the clinic was 21.1 +/- 17.4 months. Survival was higher among patients treated by successive embolization of the hepatic and splenic arteries than in those treated by occlusion of one of these vessels. Comparative analysis showed that embolization of arteries of the hepatolienal zone prolongs the life of patients with complicated forms of portal hypertension in cirrhosis of the liver.

Adolescent

[Potentialities of angiography in the diagnosis and treatment of angiosarcoma of the liver].

Clinicoroentgenological evidence is described for 3 patients with nonresectable hepatic angiosarcoma. Two of these underwent therapeutic embolization of hepatic artery. Differential diagnosis between angiosarcoma and other hepatic malignancies by angiographic images seems impossible. Hepatic artery embolization can be employed as palliative treatment of advanced angiosarcomas.

Adult

[Blood supply of malignant tumors of the liver after embolization of the hepatic artery].

Repeated angiographic studies (10 arteriographies, 3 percutaneous transhepatic portography) were performed in 10 patients with malignant tumors of the liver 5-20 months after embolization of the hepatic artery. The ++roentgenological data obtained and results of 3 autopsies enabled the authors to make a conclusion that blood supply of malignant tumors of the liver after embolization of the hepatic artery remains mainly of arterial type.

Angiography

[Value of oil angiography of the kidneys in obtaining long-term contrast visualization of kidney tumors].

Angiographic examinations with oil roentgenopaque drug iodolipol were performed in 151 patients with tumors of the kidneys. Selective accumulation of iodolipol in the zones of malignization was revealed. No complications resulting from the administration of the drug were observed. Embolization of the renal artery was followed by shrinkage of the malignant tumor which practically stopped within 10-14 days.

Adult

[Prognostic value and possibilities of the treatment of arterio-portal fistula in tumors of the liver].

Angiograms demonstrated arterio-portal shunts in tumors of the liver in 15 patients. Five patients received symptomatic therapy, all of them died from hemorrhage from varicose esophageal veins in the immediate 2 months. Resection of the liver was performed in 4 patients, 3 of them are alive and in a state of remission. Esophageal hemorrhage developed only in 2 of 6 patients who underwent embolization of the hepatic artery. It is concluded that the prognosis is extremely unfavourable in untreated patients with marked arterio-portal shunting in the hepatic tumor. Such patients must be treated surgically or, if inoperable, by radiologically-guided intervention, which makes it possible to normalize portal hemodynamics in most cases and avoid fatal hemorrhage.

Adult

[Embolization of the hepatic artery in hemangiomas of the liver].

Embolization of the proximal part of the hepatic artery was carried out in three patients with hemangioma of the liver who did not meet the criteria for radical surgery. Metal spirals were used for this purpose. Response was observed in all the cases. Patients were followed for 9-36 months. The data obtained suggest that embolization of the hepatic artery is effective and may be used for the treatment of inoperable vascular tumors of the liver.

Adult

[Choice of the approach in catheterization and embolization of the hepatic artery in malignant tumors of the liver].

The results of catheterization (transfemoral and transaxial) and embolization of the hepatic artery in 67 patients with malignant hepatic tumors are analysed. In patients with hepatomegaly, the unfavourable topographic-anatomical interrelations of the intraorganic hepatic vessels were established. Distribution of the vessels more accurately is defined by means of ultrasonography. In detection of the unfavourable anatomical factors, the more wide use of primary transaxial catheterization of the hepatic arteries without an attempt of transfemoral catheterization is recommended.

Catheterization

[X-ray endovascular embolization of the hepatic artery in the palliative treatment of hepatocellular cancer].

X-ray endovascular embolization of hepatic artery (HAE) was carried out in 10 cases of liver cell carcinoma (hepatic cirrhosis included). Immediate beneficial effect was recorded in 8 cases. Remission for 12 months and more was registered in three cirrhosis-free patients; mean survival in five patients was 15 months. In cases of cancer aggravated with cirrhosis, HAE effectiveness proved much lower and survival dropped to average 5.5 months.

Adult

[Roentgenoendovascular occlusion in patients with cancer of the kidneys].

Roentgenendovascular occlusion of the renal artery was used in 116 patients with renal carcinoma, in 70 of them the embolization was performed as a preoperative measure 3-12 days (7 days at an average) before nephrectomy. Embolization was also performed in 46 patients with spreaded renal carcinoma with metastases or with somatic diseases preventing surgical interventions. The roentgenendovascular occlusion reduced the time of operation and blood loss in nephrectomy, especially in patients with great hypervascularized tumors. In patients with inoperable renal carcinoma embolization was followed by arrest of hematuria, relief of pain and prevented progress of the disease.

Adult

[Pharmacolymphography].

With the goal of accelerating the contrast-medium injection at the lymphography and improving the contrasting of the vessels and node conduction system the authors applied a variety of pharmacological preparations: Ridol (G. Richter), Nospanum (Quinoine, HPR), Arfonadum (Hoffman-La Rochet, Switzerland), Xavinum (Quinoine) etc. in 110 cases of various malignant neoplasms. All the selected drugs are, to a greater or lesser extent, of a vasodilative effect. It has been found that Ridol together with the combination of Novocaine and Nospanum produce a pronounced lymphotropic effect. Pharmacolymphography with these preparations contributes to the shortening of the time necessary for the injection of contrast-medium and also improves the image of the intermediate node sinuses and of the thoracic duct.

Adolescent