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Biomedical subjects

V K Kak

Publications and source records attributed to V K Kak.

At least 73 records · Page 4Linked to original sources
PubMed1990

Persistent Cushing's disease in a patient with invasive pituitary adenoma.

A patient with invasive basophilic pituitary adenoma is described, in whom the hypercortisolaemia and clinical features persisted despite two attempts to reduce the tumour mass by transfrontal pituitary surgery and external beam radiotherapy. The patient responded to oral ketoconazole with clinical and biochemical improvement.

Adenocarcinoma↗
PubMed1989

Gliosarcoma with cartilage formation.

A case of gliosarcoma with cartilaginous component is described. Immunohistochemical and electron microscopic studies confirmed the presence of glial and fibroblastic elements. A major part of the sarcomatous tissue was undifferentiated and not labeled by any of the markers used including those for endothelial cells. The cartilage cells also were not labeled either by antiglial fibrillary acidic protein or any other marker. The occurrence and histogenesis of cartilage in gliomas and gliosarcomas have been reviewed.

Brain Neoplasms↗
PubMed1989

Ossified epidural haematoma. Report of two cases.

Two patients of ossified epidural haematoma (EDH) following ventriculoperitoneal shunt for hydrocephalus are reported. Pathogenesis of an ossified EDH is discussed with special emphasis on post-shunt chronic EDH.

Adult↗
PubMed1989

Malignant schwannoma of brachial plexus presenting as spinal cord compression.

A 40-year-old male presented clinically with features of C6 radiculomyelopathy. An intradural extramedullary malignant schwannoma was removed at laminectomy. Foraminal extension of the tumour could not be removed in spite of foraminotomy, and no root attachment was found. Frequent intraspinal recurrences were treated with local resection. Delayed appearance of a supraclavicular mass, CT scan and exploration of supraclavicular fossa disclosed its origin from the upper trunk of brachial plexus.

Adult↗
PubMed1989

Thoracic disc herniation in acromegaly.

Herniation of a thoracic disc in an acromegalic giant is reported. Degenerative changes in the spine in association with dorsal kyphosis, and the additional strain, resulted in the disc prolapse.

Acromegaly↗
PubMed1989

Tension pneumocephalus following evacuation of chronic subdural haematoma.

Five cases of a rare complication of tension pneumocephalus following evacuation of chronic subdural haematoma are described. This occurred in 8% of all cases of chronic subdural haematoma treated following installation of a CT scanner. The chronically compressed brain contributes to the ingress of this intracranial air. The increase in the brain bulk and gradual re-expansion of the brain, in the early postoperative period, competes with the trapped subdural air resulting in a rise in intracranial pressure leading to neurological deterioration. Twist drill craniostomy and aspiration, using a brain cannula with a three-way connector, has produced excellent results.

Child↗
PubMed1989

Medulloblastoma in adults--clinical observations and results of treatment.

Ten cases of medulloblastomas, in patients above the age of 15 years, were treated during a 11 year period. These constituted 18 percent of all medulloblastomas and 1.2 percent of all primary brain tumours in adults during the same period. The majority of patients (80%) were between 16 and 25 years of age, and 80 percent were male. Half the patients presented within three months of the onset of symptoms. The usual clinical presentation was with features of raised intracranial pressure and cerebellar involvement. A lateral location of the tumour and its desmoplastic variant were common. Three patients survived more than five years. The desmoplastic variant and a gross total resection of the tumour favourably affected the prognosis. Posterior fossa recurrence was the chief cause of therapeutic failures. All the recurrences developed within three years of the initial diagnosis, and were fatal within six months of their detection.

Adolescent↗
PubMed1988

Multiple subdural abscesses following colonic perforation--a rare complication of a ventriculoperitoneal shunt.

A case of colonic perforation by a ventriculoperitoneal shunt, its subsequent migration and protrusion from the anal orifice is reported. The shunt reservoir and ventricular catheter were removed percutaneously, and the disconnected peritoneal catheter was pulled out through the anus. Blood culture grew Klebsiella pneumoniae and Streptococcus fecalis. CT scan showed multiple subdural abscesses with evidence of ventriculitis. Removal of the shunt (as described), evacuation of subdural pus and systemic antibiotics resulted in complete recovery.

Anal Canal↗
PubMed1988

Brain abscess following insertion of skull traction.

A case of brain abscess developing 2 weeks after insertion of skull tongs is reported. The abscess was treated with aspiration and appropriate antibiotic therapy and its complete resolution was confirmed by CT scan. The pathogenesis, through retrograde spread of superficial infection to durocortical veins, is discussed in the light of serial CT scans at different stages of formation and treatment of the abscess.

Adult↗
PubMed1988

Spontaneous extrusion of peritoneal catheter through intact abdominal wall.

A rare occurrence of spontaneous extrusion of a Denver peritoneal catheter through the right flank in a 14-year-old boy is reported. The firm texture and short length of the catheter coupled with its movements with respiration produced a hammer effect and eroded the abdominal wall. Disconnection of the peritoneal catheter from the chamber and pulling out the extruded catheter is suggested as a simple and effective method of removal of the shunt.

Abdominal Muscles↗
PubMed1988

Craniovertebral anomalies: a study of 82 cases.

Eighty-two cases of craniovertebral anomalies have been analysed. Fifty of these were operated upon. Congenital atlanto-axial dislocation was the commonest anomaly encountered (56.1%). Multiple anomalies were frequently seen (48.8%). Common combinations were atlanto-axial dislocation with occipitalisation of atlas, basilar invagination with Arnold-Chiari malformation and basilar invagination with occipitalisation of atlas. There was a high incidence (50%) of neck deformity and/or a low hairline which provided a good clue to the diagnosis. Precipitating factors, paroxysmal symptoms and an acute onset were common in cases of atlanto-axial dislocation. Cranial nerve and cerebellar dysfunction were common in cases with multiple anomalies. Thirty-six (72%) patients improved following surgery, and three died.

Abnormalities, Multiple↗