[Renal biopsy and classification of glomerulonephritis (author's transl)].
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Biomedical subjects
Publications and source records attributed to V J Ojeda.
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A case of oat cell bronchial carcinoma that clinically simulated liver cirrhosis is reported. Post mortem findings included the very unusual intrasinusoidal pattern of liver metastases.
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A simple method of perfusion of the lungs at necropsy was used in a series of 293 necropsies. The lungs were examined 24-48 hours after fixation. Two hundred and eighty-eight cases (98.3 percent) showed abnormalities and 92 of them (31 percent) showed multiple pathology. Unexpected pulmonary thrombo-embolic disease was found in 38 cases (12.9 percent) and the lungs were normal in only five cases (1.7 percent). The technique is simple and is advocated as a means of investigating lung pathology at necropsy.
A classification of glomerulonephritis which is being used as a basis for the New Zealand National Study of Glomerulonephritis is presented, together with comments about the salient pathological features of each type of glomerular disease.
The pathology of 1058 samples of kidney tissue studied during the past seven years as part of the renal biopsy service in Auckland is reviewed. About half of the samples were examples of glomerulonephritis, with diffuse proliferative and exudative glomerulonephritis being the most common finding. In the group of focal glomerular disease, lupus nephropathy and Goodpasture's Syndrome were frequently diagnosed.
A 31-year-old woman became unconscious shortly after delivery of a stillborn fetus in the thirty-sixth week of gestation. Tonic-clonic seizures and deepening coma occurred soon after delivery. Despite intensive supportive therapy, the patient died three days after delivery. A superior sagittal sinus thrombosis and extensive bilateral cerebral infarction were found on necropsy.