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Biomedical subjects

V J Ojeda

Publications and source records attributed to V J Ojeda.

At least 55 records · Page 3Linked to original sources
PubMed1983

Neoplastic angioendotheliosis of the spinal cord. Case report.

Neoplastic angioendotheliosis was found exclusively in the spinal cord vessels of a 76-year-old man who died after spinal shock. Neoplastic angioendotheliosis limited to the central nervous system (CNS) has been reported once before; but CNS involvement in disseminated neoplastic angioendotheliosis has been detected in 17 cases, three of them with the spinal cord affected. The present case is apparently the first in which neoplastic angioendotheliosis has been limited to the spinal cord.

Aged↗
PubMed1983

Primary extradural neoplasms causing spinal cord compression.

Thirteen patients presented primary extradural neoplasms compressing the spinal cord and/or roots in a four year period. Laminectomy and tumour excision or biopsy were carried out in twelve patients and transthoracic resection in the one remaining. Six tumours were benign; two were neurofibromata associated with von Recklinghausen's disease; two were osteochondromata; and there were single cases of cavernous haemangioma and aneurysmal bone cyst. All patients are alive and well; follow-up ranges between 1.3 an 8.5 years post-operation. Among the malignant neoplasms there were three malignant lymphomata, two Ewing's sarcoma and single instances of mesenchymal chondrosarcoma and chondrosarcoma of the classical type. Four patients are alive, having been followed up between 3.5 to 5 years.

Adolescent↗
PubMed1983

Polyarteritis nodosa affecting the spinal cord arteries.

Necrotising arteritis was found in the spinal arterial branches of the lumbar spinal cord and in skeletal muscles, bones, peripheral nerves, and most viscera, except lungs and brain, of a 41-year-old female who died after a protracted illness finally characterized by severe paralysis due to progressive peripheral neuropathy. Spinal cord vascular involvement in polyarteritis nodosa (PAN) is rarely reported despite the high incidence of neurological complications of this disease.

Adult↗
PubMed1982

Primary colo-rectal linitis plastica type of carcinoma: report of two cases and review of the literature.

Linitis Plastica type of carcinoma can arise primarily in the colon or rectum. Fifty-two cases have been reported in the English medical literature over a 50-yr period. Two new cases are described. One patient had primary linitis plastica of the ascending colon, the other being in the rectum. Both patients died of widespread malignancy within 10 mth of diagnosis, the fate of most of the reported cases. This rare manifestation of colo-rectal carcinoma carries an ominous prognosis.

Adenocarcinoma, Scirrhous↗
PubMed1982

Necrotizing myopathy associated with steroid therapy. Report of two cases.

A range of histological lesions was found in necropsy samples of skeletal muscle from 2 patients on steroid therapy. There were perifascicular necroses, regeneration, atrophy, and sclerosis. These findings disagree with published data from human material; however, they are similar to observations made in experimentally induced steroid myopathy in rabbits.

Adrenal Cortex Hormones↗
PubMed1981

A fatal case of meningoencephalitis due to a free-living amoeba of uncertain identity--probably acanthamoeba sp.

There are 2 main types of meningoencephalitis caused by free-living amoebae. The first is a well-defined acutely fatal disease resembling fulminating bacterial meningitis. It is caused by the single species Naegleria fowleri. The second is a more poorly defined disease that runs a subacute or chronic course and is characterized by focal granulomatous lesions in the brain. The causative organisms are probably Acanthamoeba sp. in most cases, but it is possible that other genera may be involved. The first case of the subacute form of the disease to be recognized in Australia is described. A 2 1/2-yr-old, previously well girl presented with ataxia and lower motor neurone paralyses. The cerebrospinal fluid was pleocytic and she was thought to be suffering from a relatively minor viral brain-stem encephalitis. Her symptoms persisted in a peculiarly fluctuating way for 30 d when she suddenly collapsed and died from an intracranial haemorrhage. Necropsy showed focal granulomatous lesions associated with necrotizing vasculitis in the basal regions of the brain. The lesions contained well preserved free-living amoebae which were morphologically different from N. fowleri and most closely resembled Acanthamoeba sp. The ultrastructure of the organisms was particularly well preserved and is described in some detail. Immunohistological studies also excluded N. fowleri but were inconclusive for Acanthamoeba or other genera of free-living amoebae. Difficulties with the diagnosis and treatment of this disease are discussed and some practical suggestions are made.

Amoeba↗
PubMed1979

Histological staining of hepatitis B antigen in paraffin embedded liver tissue.

Two hundred and six unselected liver biopsies were stained with Gomori's aldehyde fuschin, aldehyde thionine, and a modified orcein stain, according to Shikata and others (1974). Six cases showed positive cytoplasmatic staining indicative of hepatitis B antigen. It is suggested that one of these methods should be used in the study of liver biopsies, as an additional tool in the detection of hepatitis B carriers.

Hepatitis B Antigens↗
PubMed1979

Spitz Naevi.

Twenty-four benign melanocytic tumours from children and adults (range 1-31 years of age) excised at Auckland Hospital between 1967-1977 are defined as Spitz naevi. The necessary to differentiate these tumours from malignant melanoma is stressed.

Adolescent↗
PubMed1979

The pathology of hysterectomy specimens.

Six hundred and twenty-one hysterectomies were performed at National Women's Hospital, Auckland, during 1975. Abnormal vaginal bleeding was the clinical indication in 50.72% of the cases. Fibroids, pelvic mass, prolapse, stress incontinence and cervical neoplasia were the indication for 45.88% of the cases. Total hysterectomy was performed in 618 (99.5%) patients whilst sub-total hysterectomy was done in only three cases. Histopathological studies revealed that 567 (91.30%) specimens were pathological and there was multiple pathology in 55.87% of the specimens. Leiomyomas were present in 278 cases (44.76%); microleiomyomatosis in 178 specimens (22.66%); endometrial hyperplasia in 139 specimens (22.33%) adenomyosis in 87 cases (14.00%); malignant diseases in 76 cases (12.23%); and endometriosis in 40 specimens (6.44%). There were no histological abnormalities in 54 specimens, 8.69% of this series.

Adult↗