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Biomedical subjects

V Ionescu

Publications and source records attributed to V Ionescu.

At least 109 records · Page 6Linked to original sources
PubMedDate not supplied

Epidemiologic particularities of influenza in 1986 in a large urban centre of Romania.

The study presents the evolutive peculiarities of the epidemiologic influenza process in 1986 in a large urban centre in Romania, inferrable from the active control by a complex methodology based on clinical, epidemiologic and laboratory investigations. The prevalent part of A (H1N1 and H3N2) and B influenza viruses in causing seasonal morbidity risings is being stressed. A (H3N2) and B influenza viruses determined an epidemic rising during the first trimester and A (H1N1) and A (H3N2) during the fourth trimester in 1986. The epidemiologic influenza impact in 1986 is discussed from the point of view of the complex relationships between the antigenic structure of circulating influenza viruses and the antiinfluenza immune structure of the population.

Adolescent↗
PubMedDate not supplied

QT alterations and cardiodynamic parameters in old myocardial infarction.

Prolonged QT interval in patients with old myocardial infarction was noticed as a marker of poor prognosis. The sensitivity of this functional electrocardiographic scar was augmented in 82 patients with old myocardial infarction by recording the recumbent and orthostatic electrocardiogram, phonocardiogram and carotid piezogram. The incidence of abnormally prolonged QT intervals and increased QT ratios was three times higher in orthostatic posture than in patients lying down. Abnormal QT intervals in standing position correlate also with abnormal PEP/L VET ratio and severe electrocardiographic alterations and may become a useful tool for a more accurate prognosis in patients with old myocardial infarction.

Aged↗
PubMedDate not supplied

Phonocardiographic changes induced by neuropsychic stress.

We studied the changes occurred in the electrocardiograms, phonocardiograms, apexocardiograms, carotid pulse tracings and blood pressure in 21 healthy men, range 18 to 45, before and during performing timed mental arithmetics. Besides well-known significant increase in heart rate, systolic blood pressure, differential blood pressure (no significant rise in diastolic blood pressure was observed) several phonocardiographic abnormalities were recorded: a significant increase in amplitude and number of vibrations of the early systolic ejection sound and a prominent fourth sound. In general the preexistent third sound diminished after mental stress. In young subjects--range 18 to 30--the ratio of preejection period versus ejection period was lower after mental stress as hyperkinetic conditions occurred whilst in adults the ejection period shortened. The detected phonocardiographic abnormalities reflected significant changes in contractility and compliance of myocardium and great vessels. These abnormalities may account for some cardiac dysfunction in patients with ischemic heart disease subjected to neuropsychic stress and may be misinterpreted for more severe pathological changes.

Adolescent↗
PubMedDate not supplied

Effects of crinofizin administration in experimental diseases with protein anabolism disorders. Studies in the rat.

The effects of the treatment with Crinofizin, a pineal peptide extract, on certain parameters of the protein metabolism, altered in rat by prolonged deficiency of endogenous insulin (study on animals with streptozotocinic diabetes) or by administration of large doses of cortisone, were studied. The results demonstrated the anabolic effects of the pineal extract treatment which improved the diabetic syndrome and counteracted some catabolic effects subsequent to insulin deficiency, such as weight loss and decrease in the nucleic acid concentration in the liver, or to cortisone excess, such as nitrogen loss. The data obtained open new prospects for the use of Crinofizin in the management of degenerative endocrine diseases through anabolizing hormones failure or catabolizing hormones excess.

Animals↗