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Biomedical subjects

V G Kukes

Publications and source records attributed to V G Kukes.

At least 91 records · Page 5Linked to original sources

[Use of beta-stimulators in chronic ischemic heart disease with complete atrioventricular block complicated by congestive circulatory insufficiency].

In 23 patients with full atrioventricular block and congestive heart failure developing against the background of chronic ischaemic heart disease Isuprel was injected intravenously at a speed of 1 to 3 muG/min. A positive chronotropic effect of the drug was observed and attributed to the dose employed. Isuprel produced a positive dynamics in the structure of the cardiac cycle in the treated patients. A course of such therapy resulted in a reduction, or even disappearance of the circulatory insufficiency signs in the majority of patients, but sinus rhythm could not be restored in either of them. The noted side effects were typical of beta-stimulators. Two patients developed anginal pains in the zone of the heart when the drug was given intravenously.

Adrenergic beta-Agonists↗

[Use of coronaroactive agents with beta-stimulating effect in ischemic heart disease].

In feline experiments and 65 clinical cases of ischaemic heart disease the efficacy of a new beta-stimulating agetn -- Ildamen -- was studied, the obtained effect was compared to that of Euphillin. Ildamen was found to be highly effective in patients with a moderately decreased coronary reserve and without atherosclerotic lesions in the coronary vessels.

Adrenergic beta-Agonists↗

[Changes in the protein and energy metabolism and their correction in patients with circulatory insufficiency].

Chronic hypoxia arising in cases of circulatory insufficiency brings on changes in all kinds of metabolism, including that of energy and protein. Patients suffering from circulatory insufficiency should be treated with due regard for metabolic shifts occurring in cases of cardiac incompetence. A total of 180 patients with circulatory insufficiency of the I-IIIstage were examined by employing up-to-date methods in studying the state of the energy, carbohydrate, protein, amino acids metabolism and the hepatic function. The patients underwent medication with drugs influencing the metabolic processes and with combinations of such drugs and the clinical effect of such a type of the treatment is assessed.

Adenosine Triphosphate↗

[Use of cardiac glycosides in chronic circulatory insufficiency].

Features specific for the action produced by the most widely employed cardiac glycosides (strophanthin, corglycon, proscillardin A, methyl- and acetyldigoxine, isolanide, digoxine and digitoxin) on the hemodynamics, peripheral resistance, electrolyte composition, acid-base equilibrium, the blood adenyl system, etc were studied in 375 patients with different stages of chronic circulatory insufficiency. The data thus made available allowed some suggestions to be made as to the choice of cardiac glycosides, the duration of their application, possible combinations thereof, and also to propose a number of measures aimed at preventing the development of poisoning with cardiac glycosides.

Adolescent↗