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Biomedical subjects

V C Roberts

Publications and source records attributed to V C Roberts.

At least 91 records · Page 5Linked to original sources
PubMed1971

Prevention of early postoperative deep vein thrombosis by intermittent compression of the leg during surgery.

A clinical trial is described in which the effect of intermittent compression of the lower limb during surgery on the incidence of early postoperative deep vein thrombosis was assessed. Deep vein thromboses were diagnosed by the (125)I-fibrinogen uptake test. Peroperative intermittent compression was achieved by means of an inflatable plastic splint coupled to a pneumatic controller. By compressing only one leg of each patient, each patient acted as his own control.With a sequential statistical analysis, 39 patients were required to pass the 5% level of significance. Eleven thrombi were detected in the control (uncompressed) legs and two occurred in the compressed legs; one of the latter was bilateral. The investigation shows that increasing the pulsatility of the venous flow in the leg is a potent prophylactic against postoperative deep vein thrombosis.

Adult↗
PubMed1971

Effects of externally applied pressure on the haemodynamics of the lower limb.

The effects of externally applied pressure of 5-150 mm Hg on the haemodynamics of the leg of dog and man were investigated. The criteria used for the assessments included femoral arterial and venous blood flow as well as vascular hydraulic conductance. The results indicated that external pressure of 5 mm Hg results in a very small non-significant increase in the femoral arterial and venous flow. Higher external pressure of 15 mm Hg or more significantly reduces the femoral arterial and venous flows as well as the vascular conductance. It therefore seems that compression produced by bandaging in horizontal supine subjects has little or no haemodynamic value and may prove to be harmful unless carefully controlled.

Animals↗
PubMed1971

Passive flexion and femoral vein flow: a study using a motorized foot mover.

The effect of rhythmic passive flexion of the foot on femoral vein blood volume flow rate has been investigated in 11 patients undergoing surgery for varicose veins. With rates of flexion varying from 24 to 50 per minute and with amplitudes varying from 20 degrees to 50 degrees it has been shown that the peak femoral vein flow can be increased to twice its normal value and that its pulsatility can be increased elevenfold. These increases are proportional to both the rate and the amplitude of the flexion, the maximum occurring, theoretically, when the foot is flexed +/-28 degrees about a line perpendicular to the leg.The investigation has further shown that the effects of sustained passive flexion are maintained, without appreciable dimunition, for 30 minutes and that the maximum increases are produced in those patients who have the lowest resting flows. It is suggested that per-operative passive flexion of the feet may be a good prophylactic against postoperative deep vein thrombosis.

Blood Flow Velocity↗
PubMed1971

Prevention of early postoperative deep vein thrombosis by passive exercise of leg during surgery.

A clinical trial assessed the effect of passive exercise of the lower limb during surgery on the incidence of early postoperative deep vein thrombosis. Thrombosis was diagnosed by means of the (125)I-fibrinogen uptake test. Passive exercise of the lower limb during the operation was achieved by using a motorized foot mover designed for use on supine subjects, and by pedalling only one leg each patient acted as his own control.In a sequential statistical analysis, 47 patients were required to reach the 5% level of significance. Thrombosis was detected in 11 control (unpedalled) legs alone, and in only one pedalled leg alone. Two patients developed thrombosis bilaterally. The investigation shows that the incidence of early thrombosis in legs which were exercised during surgery was reduced by 77%.

Adult↗