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Biomedical subjects

V Bhatnagar

Publications and source records attributed to V Bhatnagar.

At least 145 records · Page 8Linked to original sources

Long-term follow-up of Hirschsprung's disease: review of early and late complications.

OBJECTIVE: Long term follow-up of Hirschsprung's disease to determine the early and late complications. DESIGN: Retrospective. SETTING: Tertiary care referral hospital. SUBJECTS: Fifty children who underwent either Swenson's procedure [SP] (n = 16) or Martin's modification of Duhamel's procedure [MDP] (n = 34), for treatment of Hirschsprung's disease during the period 1981 through 1990. RESULTS: Early complications observed were anastomotic leak (n = 4), stenosis (n = 8), wound infection (n = 8), and intestinal obstruction (n = 6). Follow-up period ranged from 2-10 years. Long term complications included constipation (n = 1), enterocolitis (n = 2), mild soiling (n = 4), and intestinal obstruction (n = 2). CONCLUSIONS: Early complications were seen with equal frequency in patients with either SP or MDP but late complications were seen less often with the SP. Both SP and MDP were equally effective in the definitive treatment of Hirschprung's disease.

Anastomosis, Surgical↗

Management of metastatic Wilms tumor: an eleven year experience.

During the last 11 years, 101 patients of Wilms tumor were seen. Of these, 13 patients had metastatic disease at onset while 24 patients presented with relapse at a latter date. Seven patients have been cured, all had favourable histology. The risk factors associated with relapse were found to be unfavourable histology, lymph node involvement, age more than 6 years, diffuse spill, capsular and vascular invasion, and aneuploidy. Of the 18 patients who had relapsed, 14 were found to be aneuploid. Judicious use of various therapeutic options like radiotherapy to metastatic sites, second look surgery, resection of pulmonary metastasis and use of cis-platinum, VP-16 and Ifosfamide as "alternative chemotherapy protocols" were used to achieve cure in these advance cases.

Child↗

The incidence and management of biliary complications following liver transplantation in children.

Biliary complications following liver transplantation are a cause of significant morbidity and mortality. During the period 1988-1993 ten cases of biliary complications occurred after 98 transplantations in 78 children. The complications were four bile leaks, three intrahepatic biliary strictures (one with recurrent cholangitis), two anastomotic biliary strictures (one with recurrent cholangitis) and one recurrent cholangitis. All leaks occurred within 6 weeks of transplantation whereas all strictures and cholangitic episodes occurred after 3 months. Two biliary complications (20%) - one intrahepatic and one anastomotic stricture - developed secondary to hepatic artery thrombosis. The incidence of biliary complications was 13.2% with whole liver grafts as compared to 6.7% with partial liver grafts and it was 4.3% with duct-to-duct anastomosis as compared to 12.0% with Roux-en-Y hepatico-jejunostomy. Seven children required intervention for management of biliary complications and three were managed conservatively. There were no deaths related to the biliary complications.

Adolescent↗

Congenital segmental giant megaureter.

A case of congenital segmental giant megaureter is reported. The patient presented with an asymptomatic abdominal mass resulting from the megaureter. A mildly hydronephrotic ipsilateral kidney was palpable as a separate mass. The ureter proximal and distal to the dilated segment showed normal peristaltic activity. Treatment consisted of excision of the dilated segment, with end-to-end ureteric anastomosis.

Child, Preschool↗