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Biomedical subjects

V Bhatia

Publications and source records attributed to V Bhatia.

At least 73 records · Page 4Linked to original sources

Hepatic visceral larva migrans: evolution of the lesion, diagnosis, and role of high-dose albendazole therapy.

An unusual presentation of hepatic involvement of visceral larva migrans is described. A 45-yr-old male presented with fever, pain in the right upper quadrant, and persistent eosinophilia. Ultrasound initially detected a solitary hypoechoic area in the right lobe of the liver which rapidly progressed to multiple lesions with peripheral hyperechoic lesions. Aspiration from the lesion revealed Charcot-Leyden crystals and sheets of eosinophils. Serology for Toxocara canis was strongly positive. Prolonged and high-dose albendazole therapy, in combination with antibiotics, was required to treat the patient effectively.

Albendazole↗

Adrenal tumor complicating untreated 21-hydroxylase deficiency in a 5 1/2-year-old boy.

OBJECTIVE: A 5 1/2-year-old boy presenting with virilization was diagnosed as having classic 21-hydroxylase deficiency complicated by an adrenal tumor. We attempted to document a reduction in the size of the tumor with glucocorticoid therapy. DESIGN: Case study. SETTING: Referral center. INTERVENTION: Glucocorticoid therapy was instituted for congenital adrenal hyperplasia. Surgery for the adrenal mass was deferred, and the size of the mass was monitored by serial ultrasonography. RESULTS: Baseline values of serum 17 alpha-hydroxyprogesterone (186.6 nmol/L) and testosterone (24.7 nmol/L [7.1 ng/mL]) were elevated. After instituting steroid treatment, 17 alpha-hydroxyprogesterone was suppressed (13.0 nmol/L), and testosterone remained undetectable on follow-up. However, the size of the mass increased during 6 months. Unilateral adrenalectomy performed at that time revealed a well-encapsulated adenoma in a hyperplastic gland. CONCLUSIONS: Untreated classic congenital adrenal hyperplasia may be complicated by an adrenal tumor even at a young age. Suppression of adrenal androgens by glucocorticoid therapy was not accompanied by regression of the tumor in our patient.

Adenoma↗

Extracorporeal shock wave lithotripsy for vesical lithiasis: initial experience.

The classical treatment for vesical lithiasis consists of surgery or endoscopic transurethral disintegration. These procedures require anaesthesia and hospitalisation. We report our experience with the Siemens Lithostar in 18 male patients with bladder stones. Complete fragmentation was achieved after a single session in 14 patients and 4 required 2 sessions. A 3-way Foley catheter with saline irrigation was used during treatment. Patients were treated in the prone position followed by immediate evacuation of stone fragments in 9 cases. Morbidity was minimal. Two patients developed impacted fragments and required stone retrieval. Extracorporeal shock wave lithotripsy (ESWL) for vesical lithiasis appears to be a simple, well tolerated and effective form of treatment.

Adult↗

Calculus disease in duplex system--role of extracorporeal shockwave lithotripsy.

We report 8 patients with urolithiasis in a duplex system. These patients (7 males and 1 female) underwent 16 extracorporeal shock wave lithotripsy (ESWL) treatments. Five had renal and 3 had ureteral stones. The mean stone size was 21 mm (12-54 mm). Five patients had incomplete and 3 had complete duplication, of which one had an associated horseshoe kidney. Retrograde ureteropyelography was done in all the patients and in 7 a JJ stent was inserted. The JJ stent could not be inserted in 1 patient with incomplete duplication and retrograde catheterization with saline infusion was used as an auxiliary procedure. One patient with complete duplication had stones in both the ipsilateral ureters with a stone bulk of 54 mm and required two JJ stents. Only 1 paediatric patient required general anaesthesia. The 3-month stone-free rate was 100%.

Adolescent↗

Renal milk of calcium: review of the literature and report of 5 cases.

To our knowledge only a few cases of renal milk of calcium have been reported. We have encountered 5 such patients. The diagnosis depends upon the demonstration of half-moon-shaped calcification in the lateral decubitus or upright roentgenograms. This condition should be differentiated from a renal calculus to avoid unwarranted surgery or extracorporeal shock wave lithotripsy.

Adult↗

Urolithiasis with blind-ending ureteral duplication and azotemia treated with shock wave therapy.

A case of bilateral urolithiasis and renal insufficiency with a blind-ending branch of the right bifid ureter is presented. The diagnosis was made by retrograde ureterogram which revealed a blind-ending branch originating in the middle third of the right ureter. Stones were treated with phased extracorporeal shock wave lithotripsy after preliminary bilateral JJ stenting. The renal parameters reverted to normal and the patient was stone-free.

Humans↗

"To stent" or "not to stent" less than 10 mm stones?

The role of JJ stent in ESWL treatment of less than 10 mm urinary calculi is still controversial. In our experience routine pretreatment ureteral stenting has a definitive prophylactic and therapeutic role. The pros definitely outweigh the cons of stent "for all".

Humans↗