[The role of recently identified proteins in rheumatoid inflammation].
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Biomedical subjects
Publications and source records attributed to U Ambanelli.
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The synovial lactoferrin (LF) concentrations of 59 patients with active rheumatoid arthritis were determined. The median value of LF was 4.64+/-3.59 mg/100 ml, but in degenerative arthropathy the levels of the metal-protein were much lower and often not titratable. These variations in the LF concentration explain the low blood-iron levels in inflammatory states, even when the concentration of the metal-protein is not statistically correlated in inflammatory tests, IgG, complement fractions (of the normal or alternate pathway), or variations of other protein fractions of leucocyte origin.
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Echography has been employed in 10 patients with knee effusions and in two patients with Baker's cysts. In all instances, echography clearly identified the effusions. In four patients, the presence of connective tissue septa were also shown. This technique appears to be preferred to arthrography or the intra-articular injection of isotopes. Nevertheless, echography provides only "morphologic" information which complements other methods of investigation.
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