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Biomedical subjects

T Zwergel

Publications and source records attributed to T Zwergel.

At least 55 records · Page 3Linked to original sources
PubMed1988

Results in the use of extracorporeal piezoelectric lithotripsy (EPL) for treatment of urinary calculi.

The Piezolith 2200 as an extracorporeal shock wave lithotripter uses piezoelectrically generated, high-energy sonic impulses for treatment of urinary calculi; the shock wave generator is self-focussing. Localization of concrements is performed by means of ultrasound imaging. Treatment with the Piezolith 2200 is painless for the patient and thus possible without anesthesia and analgesia. We report on 806 cases of treatment involving a total of 572 kidneys in 567 patients (561 adults, 6 children) suffering from calculi of various sizes in the renal pelvis (n = 126), calculi in the calyces (n = 384), partial (n = 24) or full (n = 19) staghorn calculi, as well as calculi in the upper part of the ureter (n = 19). In 88% of these cases the concrements could be removed completely. Since cardiac activity is not influenced by piezoelectrically generated high-energy impulses, this procedure is particularly suited to the treatment of patients with heart problems.

Adult↗
PubMed1988

[Extracorporeal shockwave lithotripsy in the treatment of urolithiasis--experiences from a center with the Piezolith 2200 and HM3 lithotriptors].

The Piezolith 2200 allows not only a qualitatively identical treatment of urolithiasis like the HM-Dornier systems or the Siemens Lithostar, but the application of lithotriptable urinary calculi could be extended to cardiac risk patients, to patients with skeletal deformities and to those with unusual body height and weight. As the piezolithotripsy does not cause pain, treatment is possible without anaesthesia or analgesia. Combined with internal ureteral stenting by self-retaining double-J-ureteral catheter also calculi with larger stone masses can be treated advantageously by exclusive piezolithotripsy as monotherapy. Multiple treatments by the piezolithotriptor are possible because of good focussing of the shock waves and the smaller parenchymal alteration. Lithotripsy of ureteral calculi is performed in the upper and lower part of the ureter. In small calculi the retrograde introduction of an ureteral catheter armed with an "ultrasound mirror" is necessary.

Combined Modality Therapy↗
PubMed1988

[Use of electronic data processing in the urologic clinic and practice--possibilities and perspectives].

The development, present status and future trends in the use of computers in urology in the Federal Republic of Germany are reviewed. The hardware, software required for hospital and private practice and the staff needed are discussed. Proposals are given for the installation and stepwise upgrading of computer systems, from simple text processing units to complex hospital communication systems. Finally new technologies that might considerably change the use of computers in urology are presented.

Computers↗
PubMed1985

Development of the prostatectomy since 1966. An analysis of 3,180 patients.

An analysis of 3,180 prostatectomies (between 1966 and 1982) reveals an increasing number to sixfold from 1966 to the end of the 70s. The preoperative preparation of the patients often suffering from several cardiovascular and especially respiratory diseases (about 40%) is improved by an early cooperation of all medical disciplines involved. Important complications such as the fluid absorption toxicity could be reduced; the excessive absorption of irrigation fluid (i.e., the TUR-P syndrome) was found in about 1.0% of the cases. Postoperative complications such as epididymitis or urethral strictures can be diminished by special surgical treatment methods.

Age Factors↗
PubMed1985

[Current status and conservative and operative therapy of urogenital tuberculosis].

In each case the primary treatment of tuberculosis is a medicamentous therapy. Using the modern basis medication of isoniazid, rifampicin, ethambutol and streptomycin at present for the normal case the short-term therapy of maximally 12 months made its way. The operative treatment of the urogenital tuberculosis is only a part of the total therapy plan. Among 715 patients nearly half of them had to undergo at least one surgical intervention from 1966 to 1983. The nephrectomy rate of 22.3% is to be classified as high and is conditioned by progressing and extended changes of the kidneys, which are in most cases recognized too late. In 69 patients partial resections of the kidney were performed. Since 1976 the indication for this intervention was in 13 cases made only intraoperatively and at the same this the planned nephropyeloplasty was performed on account of disturbance of the urine flow. Good postoperative results encourage to perform plastic reconstructive measures also in changes of the kidneys of stage III.

Aged↗
PubMed1985

[Urethral injuries--a retrospective analysis of therapeutic possibilities and late morbidity].

Injuries of the urethra confront traumatologists and urologists with common diagnostic and therapeutic problems. By an early interdisciplinary cooperation life-threatening early complications such as urosepsis, and late complications which are difficult to be corrected such as strictures of the urethra may be prevented and reduced, respectively. The accidental mechanisms and the diagnostic possibilities in injuries of the urethra are explained in detail. In 24 patients with anterior ruptures of the urethra and in 66 patients with posterior injuries of the urethra with the exception of 12 immediate operative reconstructions primarily a suprapubic and transurethral micturition was chosen. The posttraumatic results concerning the rate of stricture, the kind of removal of the stricture, the frequency of incontinence of urine and erectile impotence are analysed.

Humans↗
PubMed1984

[Surgical therapy of urogenital tuberculosis].

The surgical therapy of genitourinary tuberculosis is important as adjuvant treatment besides an appropriate anti-tuberculous drug therapy. During the years 1966-1983 surgical treatment was necessary in 46.1% (330 cases) of 715 patients. Cases, not treated properly for a long time, still have a high incidence of nephrectomy. Since 1976 more reconstructive operations and partial kidney resections have been carried out, resulting in a 5,6% rate of secondary nephrectomy. In up to 92.3% of the patients with these operations, renal function was not reduced or had improved. In cases with progressive tuberculosis of the upper urinary tract reconstructive surgical treatment is also recommended with good late results.

Adult↗
PubMed1983

[Concept of interdisciplinary procedures within the scope of traumatology--the status of urology].

Following criteria decide on the further life of patients with acute severe trauma: how fast injuries and their severity are recognized and following therapies are managed; prior conditions for a sufficient treatment of the acute trauma patient consist in a perfect organization and a good cooperation of all specialists. Important details of the therapeutic concept, divided in 5 or 6 phases are given. Furthermore special urological aspects in cases of multiple injuries are discussed.

Humans↗
PubMed1983

[Diagnosis of kidney injuries].

The exact staging of kidney damages is actually possible with the anamnesis, clinical symptomatology and different diagnostic methods. According to a greater experience the importance of the digital subtractionangiography, the sonography and computertomography is increasing The urography as a basic examination cannot be replaced by other methods, whereas only with the angiography previous to the operation the exact morphology of ruptured intrarenal arteries and injuries of the renal stalk may be found.

Humans↗
PubMed1983

[Report of experiences with therapy of kidney injuries].

Divergent opinions exist in treating severe kidney damage. Therapeutic possibilities are shown in 150 kidney injuries, analysed in a retrospective study, during an 8-year period (1975 to 1982) in an urological and surgical department. Conservative treatment was preferred in nearly all kidney trauma grade I (according to Hodges). Nephrectomy was done in 87,5% of all grade III kidney injuries. In grade II kidney damage 9.1% were managed by conservative and 90.9% by operative therapy, 78% of the injured kidneys, grade II and III, could be saved. Operative treatment is highly more recommended regardless whether kidney trauma happened with or without other injuries. Decisions between both therapeutic possibilities, conservative or operative, depend upon posttraumatic complications and the urgency of polytraumatic injuries. Early cooperation between urologist and surgeon is most important.

Adolescent↗
PubMed1983

[Bladder and urethral injuries - report of experiences].

Injuries of bladder and urethra cause diagnostic and therapeutic problems to urologists and surgeons. A retrospective study of 98 patients from 1975 until 1982 with pelvic trauma and damage of the lower urinary tract is presented concerning etiology, mechanism of accident and therapeutic possibilities, as well as the analysis of 24 patients with anterior urethra damage. In all 38 cases with ruptured bladder operation was performed. 66 patients with posterior urethra damage were treated with regard to their general status. In this study conservative management with catheter or cystostomy seems to be more favourable in posterior urethra damage than primary reconstructions especially when considering the rate of urethral structure. Furthermore problems of posttraumatic difficulties with sexual potency are discussed.

Adolescent↗
PubMed1978

Improvements of the electrophoretic mobility test to measure lymphocyte sensitization.

The Electrophoretic Mobility (EM)-test was performed in 316 children to examine their lymphocyte sensitization to a common antigen by measuring the mobility of special indicator cells. The results indicate that this test can serve as an additional help in differential diagnosis of malignant and non-malignant diseases. Measurements in the cytopherometer were facilitated by introducing several technical modifications: 1) The original method of timing with a stopwatch was replaced by two electric watches electrically combined with the cytopherometer. Thus individual faults were reduced. The next improvement of timing at the cytopherometer consisted in the construction of an electronic controller and stopwatch in combination with a minicomputer, data print out, and tape recorder in order to get more reliable results. 2) Further automatic recording of the data is time-sparing and useful for correct evaluation of the EM-test. That can be done now directly on-line in a calculator with a program developed in our laboratory. 3) By using a television monitor for the observation of the indicator particles an additional simplification is possible.

Antigens↗
PubMed1977

Electrophoretic mobility (EM)-test for childhood cancer diagnosis.

Lymphocyte sensitization to myelin basic protein (encephalitogenic factor, EF) was determined in 193 children by measuring the electrophoretic mobility of indicator particles which had been incubated with the supernatant of the lymphocyte-antigen (EF) mixture. A significant decrease in electrophoretic migration time was found in 77 of 85 children with malignant tumours localized in brain, abdomen and extremities, in 36 of 38 children with acute lymphoblastic leukaemia (all except one in hematological remission), and in all 17 patients with lymphoma, in contrast to only 1 of 10 healthy children and 14 of 48 patients with non-malignant disorders. 10 of these 14 "false positive" patients, however, had auto-immune diseases. Thus, with false negative and false positive rates of less than 10%, this test could be of diagnostic help in patients with suspected malignant or auto-immune disease. Two examples of preoperative application of the EM-test are demonstrated.

Abdominal Neoplasms↗