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T Wolf

Publications and source records attributed to T Wolf.

117 records · Page 7Linked to original sources

A cognitive model of musical sight-reading.

The author, a professional flutist and psychologist, interviewed four pianists noted for their sight-reading abilities. The results of the interviews are considered from several points of view. Sight-reading is analyzed as a problem in pattern recognition: a movement from a sonata by Handel is used to illustrate the principle of scanning for familiar patterns. The close relationship between musical sight-reading and the reading of conventional texts is also suggested. Finally, drawing on the findings of other studies, a congnitive model of musical sight-reading is proposed. The schematic model of interlocking information-processing systems explains the differences between skilled and unskilled sight-readers: it also explains why some experienced, professional musicians are poor sight-readers. Verification of the model is provided in an additional section in which conversations with unskilled sight-readers are reported.

Adolescent↗

Functional conformations of calmodulin: I. Preparation and characterization of a conformational specific anti-bovine calmodulin monoclonal antibody.

Calmodulin, similarly to many other Ca(2+)-activated proteins, undergoes considerable conformational changes in the presence of Ca2+ ions. These changes were followed using specific monoclonal antibodies against calmodulin. Since calmodulin is a poor immunogen due to its high phylogenetic conservancy, glutaraldehyde-crosslinked bovine brain extract, which contains a considerable amount of functionally active calmodulin complexed with its target proteins, was used as an antigen. Out of nine anti-calmodulin mAbs isolated, three (namely, CAM1, CAM2 and CAM4) were purified and characterized. MAb CAM1 was identified as an IgG1 while mAbs CAM2 and CAM4 belong to IgM class. Additivity ELISA showed that mAb CAM1 binds to an epitope located remote from the epitopes recognized by the other two mAbs, while mAbs CAM2 and CAM4 recognize close epitopes. MAb CAM1 was found to be especially sensitive to the conformational state of calmodulin in the presence of Ca2+ ions. The interactions of mAbs CAM2 and CAM4 with calmodulin are only slightly affected by Ca2+ removal. In addition mAb CAM1 failed to recognize other calmodulin molecules, such as spinach and various plant recombinant calmodulins, while mAbs CAM1 and CAM4 share common epitopes with the above molecules.

Animals↗

Dose-response analysis of combination preparations.

A parametric model for quantal response to combination preparations is defined and discussed. Tests for additivity of the combination preparation are specified and demonstrated by an example. Parallelism of the dose-response curves is not required.

Animals↗

The feasibility of suicide rates as an evaluation criterion in community psychiatry: methodological problems.

Over the last 30-40 years the reform of psychiatric care in many countries has led to deinstitutionalization and treatment of many patients in community psychiatric services. There is an ongoing discussion on whether this process may lead to a higher suicide rate. There are only a few studies addressing this issue, and empirical data are scarce. Several methodological problems make it difficult to use suicide rates as an evaluation criterion for community psychiatry. These problems are briefly discussed.

Berlin↗

[Osteoma cutis, a case report from the orthopedic viewpoint].

Osteoma cutis is a benign cutaneous disease which causes a primary heterotopic ossification of the skin. Corresponding to the appearance it is possible to distinguish four modifications. The enlargement of osteoma cutis can disturb the function of joints and statics. The etiology of the disease is unknown. Hamartoma or metaplasia is subject of discussion. It is important to mark off osteoma cutis from pseudohypoparathyreoidism (Albright-syndrome++).

Adult↗

Comparison of the scope of allopathic and osteopathic medical school health promotion programs for students.

PURPOSE: To compare the number and scope of health promotion programs for students in allopathic and osteopathic medical schools in the U.S. and Canada. DESIGN: A one-time cross-sectional survey design was applied in this study. SETTING: This study was conducted in 141 accredited allopathic and 17 accredited osteopathic medical schools. SUBJECTS: A total of 158 representatives from the allopathic and osteopathic medical schools participated in this study. The response rate for the survey was 100%. MEASURES: A structured telephone interview was conducted to survey representatives from the medical schools. The survey contained 85 multiple-choice questions organized into four sections: administrative characteristics, types of institutional and health promotion program policies, participation incentives and facilities, and type/scope of health promotion program activities. Chi-square analysis was used to analyze survey variables by type of medical education and level of intervention. RESULTS: Of the 158 medical schools, only 20% (n = 32) provided a health promotion program for students. Although osteopathic institutions (29.4%) had a greater percentage of programs than allopathic schools (19.2%), there was no significant difference in scope of program offerings by type of medical education. Allopathic programs offered exercise and nutrition/weight management significantly more often and at a higher level of intervention. Lastly, allopathic programs had significantly more monetary resources available for programming. Following prudent research protocol, investigators should be mindful of the limitations of this study. In this study, some school representatives chose not to answer personnel- and finance-related questions. Additionally, because of the self-report nature of the survey, the responses given to the questions may not have been accurate. CONCLUSION: Allopathic and osteopathic medical school health promotion programs for students were very similar in scope.

Canada↗