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Biomedical subjects

T Weber

Publications and source records attributed to T Weber.

At least 397 records · Page 22Linked to original sources
PubMed1983

Multiple theoretical approaches to supervision: choices in family therapy training.

The supervision techniques used in structural, strategic, family-of-origin, and experiential family therapy training are discussed and compared, with emphasis on the isomorphism between supervision and therapy in each school. The usefulness of each supervisory model is related to supervisees' needs at different levels of training. Recommendations are made about the sequence of family therapy training, including the utility of eclectic versus purist family therapy training programs for trainees at different levels of experience.

Family↗
PubMed1983

Lymphocyte subpopulations and reactivity during and after infectious mononucleosis.

T- and B-lymphocyte numbers, as well as lymphocyte reactivity to mitogens in vitro, were studied and correlated to other laboratory tests during the acute phase of infectious mononucleosis (30 patients) and up to one year thereafter. During the acute disease an absolute increase in both T- and B-lymphocyte numbers was recorded, the relative increase in B-lymphocytes occurring at the start. B-lymphocyte numbers fell after the second week and T-lymphocyte numbers after the fourth week of disease. Lymphocyte activation was impaired in all patients during the acute phase and was still significantly impaired for some mitogens after 6-9 months. Very few correlates between lymphocyte tests and other laboratory and clinical parameters were found.

Adolescent↗
PubMed1983

On the rationale of the alpha-hydroxybutyrate dehydrogenase (HBD) determination.

The discriminating power of HBD, LD and of the HBD/LD ratio in comparison with LD1/LD2 and LD5/LD4 ratios in acute myocardial infarction and hepatic disease is evaluated. The results demonstrate that there are no clinical reasons for the determination of the HBD when a method using the conditions of the Committee of Enzymes of the Scandinavian Society for Clinical Chemistry (SCE) is used.

Humans↗
PubMed1983

Epidermolysis bullosa--pyloric atresia. An autosomal recessive syndrome.

A sister and brother each had epidermolysis bullosa and pyloric atresia at birth. Both died in early infancy of complications related to epidermolysis bullosa. Electron microscopic studies of skin biopsy specimens disclosed findings consistent with a diagnosis of epidermolysis bullosa letalis. The existence of epidermolysis bullosa-pyloric atresia syndrome as a distinct clinical entity with autosomal recessive inheritance is supported by the findings in these patients.

Epidermolysis Bullosa↗
PubMed1982

[Ectopic hormone formation in multiple endocrine type IIa neoplasia (author's transl)].

A patient with high-grade osteoporosis had elevated levels of ACTH, cortisol and carcinoembryonic antigen (CEA). Computed tomography demonstrated enlarged adrenal glands. Despite intensive search no ACTH-producing tumour was found. A central Cushing's syndrome was thus possible, and a radiologically normal sella turcica made a microadenoma of the hypophysis a possibility. However, a one-time hypertensive crisis with elevated catecholamines raised the suspicion of an additional phaeochromocytoma and thus provided the first pointer to a multiple endocrine neoplasia. Bilateral phaeochromocytomas, discovered at adrenalectomy, as well as raised serum-calcitonin levels, strongly suggested coexistence of a C-cell carcinoma, which previously had not been demonstrated either by thyroid scanning or fine-needle biopsy. A total thyroidectomy revealed a multifocal and metastasizing C-cell carcinoma. On extraction it contained a high concentration of calcitonin, typical for a C-cell carcinoma. An unusual finding was of ACTH in extracts of both the C-cell carcinoma and the phaeochromocytoma. It was immunologically identical with the synthetic ACTH used as a standard.

Adrenal Gland Neoplasms↗
PubMed1982

Neonatal small left colon syndrome in twins.

There are no previous reports of small left colon syndrome in twins. Small left colon syndrome is reported in 2 sets of twins. In 1 set 1 twin had clinical and radiographic signs of small left colon syndrome. The sib was clinically normal and had no radiographic studies. In the other set, both twins had identical clinical and radiographic findings of hyperplastic left colon. This suggests a genetic and/or environmental intrauterine, rather than a postpartum etiology for the small left colon syndrome.

Barium Sulfate↗
PubMed1982

Uterine plasminogen activator activity: modulation by steroid hormones.

We have used a sensitive and quantitative assay to investigate the hormonal regulation of plasminogen activator (PA) activity in the rat uterus. PA activity is increased 5-fold (per U protein or DNA) by low physiological (0.1 micrograms) doses of estradiol, with increases in activity first observed at approximately 12 h. The stimulation of PA activity shows strict specificity among the steroid hormones, being stimulated by estrogens only or by high doses of dihydrotestosterone, which are known to affect the estrogen receptor system, and this stimulation is suppressed markedly by triphenylethylene antiestrogens. Comparative dose-response studies with a variety of estrogens of different uterotropic potencies indicate a good correlation between the potencies of different estrogens in stimulating PA activity and uterine growth (diethylstilbestrol = 17 beta-estradiol greater than estrone = 17 alpha-estradiol greater than estriol), with the exception of the zearalanol estrogen P-1496, which was consistently a potent stimulator of PA activity while being a very weak uterotropic agent. These studies suggest that increases in uterine PA levels may serve as a good marker of estrogen action in the uterus. Although the role of PA in uterine function remains unknown at present, its relatively large increase (up to 25-fold increase in content per uterus) may play a role in tissue remodeling during uterine growth.

Animals↗
PubMed1982

Metrizamide in neonatal and childhood small bowel obstruction.

Metrizamide (Amipaque) has been used to image the bowel of four neonates and one older child with possible bowel obstruction. In each case, barium and hypertonic water-soluble agents, such as Gastrografin and Hypaque, were contraindicated. In each case, the metrizamide study provided unique formation altering the management of the patient. Metrizamide provides a new method of evaluating selected difficult cases of suspected bowel obstruction in the newborn, and in older children it may help to distinguish between postoperative ileus and mechanical obstruction.

Child↗
PubMed1982

Cardiotocography supplemented with continuous fetal pH monitoring during labor. Effect on rate of obstetrical interventions and neonatal condition.

Continuous monitoring of the fetal scalp tissue pH (tpH) was performed in 96 consecutive cases. Of these 96, 72 (75%) had acceptable pH tracings which were used for the management of labor (series II). These 72 patients were compared with 72 patients from an earlier series (series I) of tpH monitoring in which pH was not used in the management of labor (matched according to age and parity). A significant decrease in the number of forceps and vacuum extractions (from 25.8 to 8.6%) and in the total number of interventions (from 36.1 to 15.3%) because of suspected fetal distress was observed when tpH was used in the management of labor. The state of the newborns (Apgar score 1 and 5 min after delivery; umbilical artery and vein pH, pCO2, base excess, standard bicarbonate, pO2, oxygen saturation, and hemoglobin) was equal in the two series, except for a slightly greater oxygen saturation of the umbilical artery and a slightly lower umbilical vein pH in series II. It is concluded that tpH monitoring of the fetus during labor can reduce the number of interventions, but the method still needs further development and clinical evaluation.

Apgar Score↗
PubMed1982

Cellular immunity during follow-up of patients with sarcoidosis of varying duration.

Cellular immunity was followed up at 3 month intervals for 1 year in 43 patients with sarcoidosis representing three well defined categories of the disease viz acute (12), subacute (20) and chronic (11). Twelve apparently healthy individuals served as controls. Each follow-up included the following tests: total number of blood lymphocytes, T cells, B cells, leucocyte migration tests with PPD, BCG and Kveim test material and stimulation tests of lymphocytes in vitro in the presence of PHA, Con A, PPD and PWM. Statistically, the most abnormal initial findings in all the tests were noted in acute sarcoidosis, followed by the subacute group. The acute group showed the most marked changes also during the follow-up. The smallest changes during the follow-up were seen in the patients with the chronic form of the disease. However, the inter-individual variation was considerable and no definite conclusions could be drawn from findings in a given case. Alterations in cellular immunity occur in sarcoidosis. They differ between different subgroups of patients and vary differently in course of time. Well defined criteria for inclusion of patients in an investigation and repeated studies of included patients will increase the information available from investigations of cellular immunity in sarcoidosis.

Acute Disease↗
PubMed1981

[Diagnosis of focal nodular hyperplasia of the liver (author's transl)].

In two female patients with hypothalamic-hypophyseal Cushing's syndrome who had not taken oral contraceptives, upper abdominal sonography showed three liver tumours as chance findings. In one case the left lobe was involved alone and in one case both lobes. None of the three tumours could be demonstrated by means of computer assisted tomography. Autopsy in one case and liver arteriography and scan in other other led to the diagnosis of focal nodular hyperplasia of the liver. These cases demonstrate the importance of sonography in the recognition of liver tumours. A connection between the overpopulation of adrenocorticosteroids and the formation or enlargement of focal nodular hyperplasia of the liver cannot be excluded.

Adult↗
PubMed1981

The influence of cord complications on fetal pH, neonatal Apgar score, and the acid base state and oxygenation of the umbilical artery and vein.

Continuous monitoring of fetal scalp tissue pH (tpH), acid base and oxygenation measurements of the blood of the umbilical artery and vein, and APGAR scoring was performed in 152 deliveries. The effect of cord complication on tpH (120, 90, 60, 30, 15, 10, 5, and 0 minutes before delivery), the status of the umbilical artery and vein (pH, pCO2, base excess, standard bicarbonate, pO2, and oxygen saturation), and the APGAR scores (one and five minutes after delivery) were investigated. Thirty-two per cent of the deliveries were associated with on or more cord complication(s). Cord complications in general did not influence the APGAR scores, the acid base state, or the oxygenation of the fetus and newborn. In the very few cases of tight cord complication(s) tpH showed a marked decrease during the last 30 minutes of labour, the umbilical blood was slightly acidotic, but the APGAR scores were normal (8-10 one and five minutes after delivery). No cases of prolapse of the cord were found. Cord complications are very common but in most cases completely harmless.

Acid-Base Equilibrium↗
PubMed1981

Direct current conversion of maternal supraventricular tachycardia developed during the treatment of a pregnant heroin addict with ritodrine.

During ritodrine (UtoparR) treatment for premature labor, a chronic heroin-addicted patient developed supraventricular tachycardia which was treated by direct current (d.c) conversion, d.c. conversion did not affect the fetus, as judged by the cardiotocogram. As heroin addicts run an increased risk or developing cardiac arrhythmia, caution is advised when treating these patients with beta-mimetics.

Adult↗