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Biomedical subjects

T Vogl

Publications and source records attributed to T Vogl.

At least 181 records · Page 10Linked to original sources

[Irradiation of chemodectomas].

The rarely occurring, slowly growing glomus tumours of the inner ear, bulbus jugularis or carotis bifurcation, according to the site of the tumour, can be the cause of loss of hearing, tinnitus, vertigo, pain and cranial nerve destruction. As a result of radiotherapy, after having applied 45 Gy, the size of the tumour decreases only very slowly. Although radiotherapy yields very good results, chemodectomas are usually operated on. However, radiation can be applied as first choice of treatment because of its simplicity and because it is well tolerated by the patient. If surgery is used as first choice the rate of recurrence is higher and one should therefore always consider the use of radiotherapy. Our own results with eight patients confirmed that glomus tumours respond well to radiation. This is generally also known from the literature on this subject.

Brain Neoplasms↗

Magnetic resonance imaging in children suffering from spina bifida.

22 children with myelomeningocele (MMC) were examined by magnetic resonance imaging (MRI). After operative closure a tethered cord was found in 78% of the patients. A primary tethered cord was detected in all patients where a lipomyelomeningocele had not been operated on yet. Additional malformations shown by MRI were hydromyelia and diastematomyelia. No correlation could be found between the degree of morphologic changes and the clinical course. In covered MMCs, MRI investigation is recommended as method of choice before operation. After operative closure a control-MRI should be performed after three months. If there are no pathological findings, further follow-up should be done by ultrasound investigation twice a year.

Adolescent↗

[Determination of T2-times of tumor and muscle tissue by nuclear magnetic resonance tomography and resonance spectroscopy--results of a comparative study].

In 13 patients the T2 values of muscular and various tumor tissues was determined by MR under in-vivo conditions. The tumors were confirmed by surgery. In 5 cases there was a neurinoma of the acoustic nerve, in 3 cases a lateral neck cyst, a granuloma of the larynx and some other pathological processes. Intraoperatively the tissues are biopsied and the T2* time is determined by spectroscopy in vitro. Both the muscular and the tumor tissue show higher mean values or standard deviations in MR measurements than in measurements by spectroscopy. The relations between muscular and tumor tissue (quotients) are comparable in neurinomas of the acoustic nerve (n. vestibulo-cochlearis) and lateral neck cysts, the granuloma of the larynx and lymph nodes of the neck, using both examination methods. Calculations of the correlation coefficients of T2 values and quotients of the muscular and tumor tissue point to tissue-specific connections between in-vivo and in-vitro measurements.

Head and Neck Neoplasms↗

[Diagnostic value of nuclear magnetic resonance tomography in space occupying lesions of the pharynx].

The diagnostic value of CT in tumours of the pharynx is limited due to the reduced soft tissue contrast of this method. In the present study we report on our own experience with MR imaging of this area. We could demonstrate that MR possesses an increasing importance in the diagnosis of tumours of the head and neck. This is mainly due to the better soft tissue contrast which can even be improved by using the paramagnetic contrast medium Gd-DTPA in certain cases.

Gadolinium↗

[Effect of types of field used in nuclear magnetic resonance tomography on core and surface temperature in the human body. Results of in vitro and in vivo experiments].

Deep and superficial body temperature was measured by in vitro and in vivo experiments, using a fluoro-optic procedure and a variety of magnetic and electromagnetic fields in the course of magnetic resonance tomography. The in vitro experiments had shown that measured temperature changes resulting from a static magnetic field were reversible and could be reproduced readily. Temperature measurements in the human body were carried out centrally (oesophageal and rectal measurements) and at the periphery (intravascular). In vivo experiments on 30 experimental subjects showed no significant changes (p = 0.05) in central or surface temperatures as a result of static or dynamic magnetic fields or electromagnetic high frequency fields.

Body Temperature↗

[Nuclear magnetic resonance tomography of the spine and spinal cord compared with computed tomography and myelography].

In cases of syringomyelia MR is superior to CT and myelography in visualisation and delineation of the extent of the process. In diagnosing spinal tumours MR is a more sensitive method than CT and myelography. MR provides additional information on sagittal and frontal planes regarding the extent of the tumour. In diagnosis of disc prolapse MR seems to be as accurate as CT or myelography. We obtained additional information in diagnosis of degenerated disc tissue. Spinal stenosis is easily recognisable. CT was superior in differentiation of bony and disc protrusion. The results show that MR has opened up new possibilities in the diagnosis of spinal diseases and will result in a reorientation of the diagnostic approach.

Arteriovenous Fistula↗

[Results of a comparative study of MR, CT and sonography of patients with primary hyperparathyroidism].

Twenty-three patients with primary hyperparathyroidism were examined by MR, CT and sonography in order to localise the parathyroid adenoma. In twenty patients, surgery was performed and the findings confirmed histologically. Fifteen patients had an adenoma in a parathyroid and in three, the adenoma was in the mediastinum. In one patient there was hyperplasia of all parathyroids. Accuracy of MR was 98%, of CT 98% and sonography 94% in previously unoperated patients and is therefore similar for these methods. This is also true for previously operated patients (four) where MR was 88% accurate, CT 83% and sonography 91%. In sixteen patients without previous operation, MR had the highest sensitivity with 79%. In previously operated patients, the sensitivity of MR and sonography was equal, with 67%, and CT was similar with 66%, MR was able to differentiate adenomas by the specific measurements of T1 and T2.

Adenoma↗

[Magnetic resonance tomography in suspected acoustic neurinoma: technic and differential diagnosis].

Sixty-five patients with suspected acoustic neuromas were examined by CT and MR; the optimal diagnostic procedures are discussed. Extrameatal acoustic neuromas (11 cases) were all diagnosed by CT and MR, but only 82% of intrameatal tumours could be diagnosed by CT combined with air cisternography. Using special surface coils and the paramagnetic contrast medium Gd-DTPA, the accuracy of MR was 100%. All tumours greater than 4 mm were demonstrated. Following clinical and neurological examination, MR is the primary diagnostic method in the investigation of acoustic neuromas.

Diagnosis, Differential↗

Magnetic resonance imaging compared with computed tomography and myelography in the diagnosis of spinal masses.

Magnetic resonance imaging (MRI) is superior to computed tomography (CT) and myelography in the demonstration and delineation of the extent of syringomyelia. In the detection of intramedullary tumors MRI is more sensitive than CT and myelography. MRI provides additional information on the sagittal and frontal planes regarding the extent of tumors. In the diagnosis of disc prolapse MRI seems to be as accurate as CT or myelography. Additional information is available with MRI in the diagnosis of degenerated disc tissue. Spinal stenosis is easily recognizable. CT was superior in the differentiation of bony and disc protrusion. The results show that MR has opened up new possibilities in the diagnosis of spinal diseases and will lead to a reorientation of the diagnostic approach.

Diagnosis, Differential↗

[Nuclear magnetic resonance diagnosis of tumors of the internal auditory canal and the cerebellopontile angle].

The diagnosis of acoustic neuromas has been continually improving. By means of gas cisternography used additionally, intracanalicular neuromas can be imaged indirectly. However, these procedures lead to a certain degree to both false positive and false negative results. With MRI, as the latest imaging technique, it is always possible to detect early stages of intracanalicular growth. When using a surface coil spatial resolution will be less than 1 mm. Our experience with this imaging technique in the diagnosis of tumours of the inner ear canal and the cerebellopontine angle is discussed and our indications for the use of MRI are presented.

Cerebellar Neoplasms↗

[Nuclear magnetic resonance tomography of the orbits. Initial experiences using the paramagnetic contrast medium gadolinium-DTPA].

In 21 patients with orbital mass lesions MRI was performed before and after administration of paramagnetic contrast medium, Gadolinium-DTPA. In comparison to the plain scan the differentiation of the tumorous tissue against the surrounding structures was improved after application of contrast medium despite a partially moderate increase in signal intensity. Especially highly vascular tumors and vessel diseases show a significant contrast enhancement. With increasing experience in larger number of patients a tissue differentiation seems to be possible.

Adult↗

[Nuclear magnetic resonance in the Hallervorden-Spatz syndrome].

Two patients (mother and son) with Hallervorden-Spatz's syndrome were examined both via CT and Nuclear Magnetic Resonance (NMR), using different measuring modes. In the patient with progressing disease pathological findings were seen in the right and left putamen with CT and NMR. All examinations in the mother with a less progressive syndrome were without any result. Information obtained via NMR did not yield significantly more relevant data than computed tomography.

Adolescent↗

[Nuclear magnetic tomography in cervical lymph node swellings].

Magnetic Resonance Imaging (MRI) and CT were performed in a patient suffering from carcinoma of the larynx with swollen cervical lymph nodes. MRI images in coronal planes give new diagnostic information about the spatial extension of pathologic findings and about the question of compression or infiltration of vessels. Exact topographic knowledge will be necessary. A subject of research is the differentiation between scar formation and tumour relapses.

Aged↗

[Nuclear magnetic tomography in otorhinolaryngology. Case reports].

Magnetic resonance imaging (MRI) promises the achievement of considerable improvements in diagnostic procedures in otorhinolaryngology. In this article, the advantages of the technique are presented and their significance in diagnosis of head and neck disorders is discussed. An important advantage is the fine and detailed representation of tumours particularly in the soft tissue of the neck and the base of the tongue, which is made possible by an enhancement of contrast and by the improved spatial imaging based on the frontal and sagittal projection plane. MRI also seems to provide a new approach to the diagnosis of tumours of the glomus jugulare and the carotid body and of acoustic neurinomas. Besides, it will be possible to obtain more detailed information on the depth of infiltration of laryngeal carcinomas with the aid of surface coils.

Diagnosis, Differential↗