Biomedical subjects
T Tsuda
Publications and source records attributed to T Tsuda.
[CT appearance of thalamic lesions in stereotaxic surgery (author's transl)].
Explore the source record for details and available documents.
Effects of glucose, insulin and FFA in food intake in the sheep.
Explore the source record for details and available documents.
CT appearances of thalamic lesions in stereotactic surgery [proceedings].
Explore the source record for details and available documents.
Cortical and thalamic evoked potentials following auditory stimulation in man [proceedings].
Explore the source record for details and available documents.
Food intake and rumen osmolality in sheep.
Explore the source record for details and available documents.
Metabolism of blood glucose in cold exposed sheep.
Explore the source record for details and available documents.
[Degradation of the parathyroid hormone in the kidney and liver (author's transl)].
The cleavage of the parathyroid hormone has been reported to take place in various peripheral tissues, especially in the kidney and liver. In order to claify the mechanism of such a degradation, bovine PTH (bPTH 1--84) and its synthetic N-terminal peptide (bPTH 1--34) labelled with 125I by the chroramine-T method (125I-bPTH 1--84) and (125I-bPTH 1--34) or labelled with horseradish peroxidase Pox-125I-bPTH 1--84 and Pox 125I-bPTH 1 34) were used to study the disappearance from the blood stream and degradation and retension in the kidney and liver after intravenous injections in male Wiastar rats, weighing approximately 200g. Degradation of PTH was also studied in vitro, using isolated cells and a homogenate of the kidney and liver. PTH labeled with 125I and Pox was more readily degraded by the kidney than PTH labelled with 125I alone, but the opposite was found in the degradation by the liver. Isolated intact kidney cells degraded PTH less efficiently than the homogenate, but the isolated intact liver cells degraded PTH more efficiently than the homogenate, indicating the prominence of an intracellular mechanism of degradation in the kidney and an extracellular mechanism in the liver.
Decreased smooth muscle side effects with 16, 16-dimethyl-trans-delta2-PGE1 methyl ester in Japanese monkey (Macaca Fuscata Fuscata).
The smooth muscle stimulating activity of a new PGE1 analog, 16, 16-dimethyl- trans delta2 -PGE1 methyl ester (ONO-802) was evaluated by simultaneously recording the EMG of the uterus and intestines, along with urinary bladder pressure, and blood pressure in pregnant and non-pregnant Japanese monkeys (Macaca fuscata fuscata). Single intravenous injections of ONO-802 in increasing dosages (0.2-5 microgram/kg) were found to be 50-100 times or more effective in inducing uterine contraction than PGF2alpha and PGE1. A mild, transient gastrointestinal muscle stimulating activity was observed, but change in urinary bladder pressure and blood pressure was not evident. ONO-802 induced uterine contractions in the pregnant animals were 10 times greater than in the non-pregnant animals. These results suggest that ONO-802 may be a suitable clinical prostaglandin for use in therapeutic abortion.
Effect of Chinese medicine "Saiko-Keishi-To" on the abnormal bursting activity of snail neurons.
Explore the source record for details and available documents.
Design and characterization of electrochemical detector for high-performance liquid chromatography and application to the determination of biogenic amines.
Explore the source record for details and available documents.
Studies on phenylalanine metabolism by use of tracer techniques. II. Measurement of distribution of L- and D-phenylalanine with their deuterated species.
Explore the source record for details and available documents.
[Chronorogical changes in activities of various enzymes including beta-galactosidase and naphthol AS-D acetate esterase of the mononuclear phagocytes in tuberculosis lesions (author's transl)].
Explore the source record for details and available documents.
[The current problems of public health nurses at Ishikawa Pref. Organized activities desired--a view of a public health nurse assigned to a municipality].
Explore the source record for details and available documents.
[Clinical evaluation of S-6436 in adult patients with acute upper respiratory tract infections (author's transl)].
Explore the source record for details and available documents.
[Prevention and treatment of infections at the time of induction therapy of acute leukemia with massive dose of oxacillin-ampicillin (author's transl)].
Explore the source record for details and available documents.
Thallium-201 imaging with color display computer system in old myocardial infarction.
In 13 patients with old myocardial infarction diagnosed with use of the electrocardiogram, coronary angiogram and left ventriculogram and in 11 patients without infarction, thallium-201 imaging with a color display computer system was carried out. In the group without infarction the average ratio of activities in two regions of interest within the myocardial wall, excluding the apex, was 1.14 (1.08 to 1.23). In the group with infarction the average ratio of noninfarcted to infarcted areas was 1.44 (1.23 to 1.78). Objective detection of infarction was possible in 12 patients (92 percent) in the group with infarction. In two patients, the earlier electrocardiographic pattern of infarction had resolved by the time of imaging. These results suggest that the sensitivity of thallium-201 imaging in the diagnosis of old myocardial infarction may be greatly enhanced by objective and quantitative analysis using a color display computer system.
Optimum humidification of air administered to a tracheostomy in dogs. Scanning electron microscopy and surfactant studies.
The effect of the inhalation of dried (less than 40% water-saturation) or humidified air (100% water-saturation at 25, 30, 35 and 40 degrees C) was studied in dogs in which a tracheostomy had been performed to determine the optimal humidity. After inhalation for various periods, the dogs were killed and pieces of lung tissue were excised for analysis of surfactant. Sections of the trachea and the primary to tertiary bronchi were taken for scanning electron microscopic examination. Structural changes were observed in the trachea of dogs inhaling dried at and in the tertiary bronchi of dogs inhaling 100% water-saturated air at 35 degrees C. No changes was observed after 24 h in dogs which had inhaled 100% water-saturated air at 25 degrees C under anaesthesia or at 30 degrees C without anaesthesia. Consequently, the optimal range of humidity was determined to be 100% water-saturation between 25 and 30 degrees C.