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Biomedical subjects

T Togawa

Publications and source records attributed to T Togawa.

At least 127 records · Page 7Linked to original sources
PubMed1985

[The f-factor (fat infiltration) in breast cancer as a new indicator for predicting the occurrence of bone metastasis].

The correlation between tumor infiltration into extramammary fatty tissues (f-factor) and bone metastasis was retrospectively analyzed in 117 patients with breast cancer. Five (10.6%) and 26 (37.1%) patients developed bone metastases among 47 f-negative and 70 f-positive subjects, respectively, and the frequency of bone metastasis was significantly higher in the f-positive than in the f-negative group (p less than 0.005). Furthermore, bone metastasis was more frequent in the f-positive than in the f-negative group among patients of the same stages, lymph node involvements, or histological types. The f-factor was suggested to be a new indicator for predicting the occurrence of bone metastasis in breast cancer.

Adipose Tissue↗
PubMed1984

Determination of cyanide and thiocyanate in blood plasma and red cells by high-performance liquid chromatography with fluorometric detection.

A method for the determination of cyanide and thiocyanate in blood plasma and red cells of humans was established. It involved high-performance liquid chromatography and fluorometric detection by the König reaction. Calibration curves for cyanide and thiocyanate were linear in the range 1-200 pmol and 2-300 pmol, respectively. Clean-up methods for the determination of cyanide and thiocyanate in red cells were also developed. These methods were applied for the determination of cyanide and thiocyanate in the blood of smokers and non-smokers.

Ascorbic Acid↗
PubMed1983

Quantitative evaluation of the pattern of shunt flow in the right ventricle and pulmonary artery of dogs with experimental ventricular septal defect.

Cineangiographic studies in patients with ventricular septal defect (VSD) have occasionally demonstrated that part of the blood across the defect is ejected immediately into the pulmonary artery (PA) passing through the outflow tract of the right ventricle (RV), but without being trapped in it. We attempted to make a quantitative evaluation of the flow of a partial shunt pathway (a direct VSD-PA pathway) that drains that part of the blood from the defect. Our method depended on a thermal dilution technique to obtain the ejection fraction of the RV and to observe a simultaneous pair of dilution curves at the roots of the aorta and PA after introduction of tracer into the left atrium. An analytical process was specially designed by incorporating a stable one-pass deconvolution technique. The method was applied to eight anesthetized dogs with acutely produced experimental VSD on the entrance of the outflow tract of the RV. The flow through the direct VSD-PA pathway was, in most cases, greater than 50 and up to 85% (mean of the eight, 57 +/- 5% SE) of the total left-to-right shunt flow. This would imply that less than 50%, and down to as little as 15%, of the total amount of shunt flow contributed to extra work of the RV in these cases. In addition, the impact on the pulmonary vasculature due to such a large amount of pulsatile flow through the direct VSD-PA pathway may accelerate the development of hypertrophy of the pulmonary vessel wall.

Animals↗