[Unconstrained records and dynamic relationship analysis of physical activity rate, heart rate and posture].
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Biomedical subjects
Publications and source records attributed to T Togawa.
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The clinical usefulness of measuring serum beta 2-microglobulin (BMG) and squamous cell carcinoma-related antigen (SCC-Ag) was studied, and it was found that both were elevated in patients with squamous cell carcinoma of the lung. In squamous cell carcinoma, serum BMG was high in patients who were more than 65 years old, whereas it was not raised in those with other histological types or with benign respiratory diseases. This increase in BMG, however, was thought to correlate with the clinical stage rather than with aging. The rise of BMG was suggested, similar to the rise of SCC Ag, to be specific to squamous cell carcinoma of the lung.
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We report a case of adult T-cell leukemia with increased uptake in both lungs which was detected by a bone scan using 99mTc-MDP. This finding is thought to have been caused by the metastatic calcification which is associated with ectopic parathormone production.
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Quantitative 201Tl and 67Ga scans were performed on 44 patients with primary lung cancer to ascertain the differences in 201Tl and 67Ga uptake by tumors; especially the crude uptake ratio (CUR) of 201Tl to 67Ga was evaluated in relation to histological type. Adenocarcinomas showed a CUR of 2.00 +/- 1.55, the greatest value among all histological types. Epidermoid carcinomas and oat cell carcinomas had CURs of 0.47 +/- 0.30 and 0.37 +/- 0.05, respectively, both showing significantly lower values than adenocarcinomas (P less than 0.01). On the other hand, adenosquamous carcinomas indicated a CUR of 0.91 +/- 0.15, an intermediate value between adenocarcinomas and epidermoid carcinomas (P less than 0.05). These results indicated that 201Tl and 67Ga uptake by lung cancer was closely correlated with histological type, and also suggested that 201Tl and 67Ga scans enabled various histogeneses of lung cancer to be visualized.
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