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Biomedical subjects

T Toba

Publications and source records attributed to T Toba.

69 records · Page 4Linked to original sources
PubMed1990

Distribution of microorganisms with particular reference to encapsulated bacteria in kefir grains.

Propagable and non-propagable kefir grains in a form resembling cauliflower florets were observed by scanning electron microscopy (SEM) and light microscopy. In propagable grains short and long rod-shaped bacteria and yeasts formed separate colonies on the outside surface and inside. Internally, filaments which derived from capsules around the cells extended radially from a population of long rod-shaped bacteria. In non-propagable grains long rod-shaped bacteria with filamentous appendages were not observed, but only short rod-shaped bacteria and yeasts. Indian ink preparations showed presence of encapsulated bacteria in propagable grains and absence of these in non-propagable ones. The above results suggest that encapsulated bacteria are responsible for propagation of kefir grains.

Animals↗
PubMed1990

[Three cases of meningitis due to Listeria monocytogenes type Ib].

Three infants having Listeria monocytogenes meningitis were admitted to our hospital in the last ten years. They were a nineteen-month-old boy, a two-year-old girl and a five-year-old girl. They were all healthy infants. The two female patients survived, while the male patient died. At autopsy, arachnoid turbid, swollen brain substance and slight bleeding under the cerebellar tent were observed. Judging from the minimal inhibitory concentration of antibiotics against the isolated L. monocytogenes, antibacterial activity of penicillin G and ampicillin was good, whereas that of cefotaxime and latamoxef was poor. In conclusion, for therapy of bacterial meningitis due to unknown origin, the combination of ampicillin and cephalosporins is necessary.

Ampicillin↗
PubMed1989

[A case of primary intracranial malignant melanoma with characteristic magnetic resonance imaging].

The authors reported a rare case of primary malignant melanoma in the central nervous system and discussed the findings of MRI. A 60-year-old male was admitted for examinations to discover the cause of his generalized tonic convulsions. On admission, he had neither neurological deficits, nor were there any abnormalities revealed during physical examination. Ct scan disclosed a slightly high-density mass with perifocal edema in the right parietal cortex which enhanced markedly after injection of contrast material. This lesion was hypointense on T1 weighted image of MRI (GE: 1.5 Tesla) and a hyperintense band was observed on the surface of the tumor. On T2 weighted image, the tumor showed iso-hypointensity surrounded by an increased signal area compatible with edema. On August 31, 1988, a gross total removal of the tumor was performed. Microscopically, it was identified as a malignant melanoma. No melanoma was found in other parts of the body during careful examinations, especially in dermatologic and ophthalmologic examinations. Characteristic findings of the hyperintense band on T1 weighted image coincided well with the pathological findings of excessive melanin deposition on the surface of the tumor, and which resulted from the paramagnetic free-radicals in the melanin. MR image may be useful for differentiation of intracranial malignant melanomas from other mass lesions.

Brain Neoplasms↗
PubMed1987

Imbalance among T-cell subsets in patients with coronary arterial aneurysms in Kawasaki disease.

The populations of T cells were studied in 46 patients with Kawasaki disease, separated into 2 groups: group I--11 patients with coronary aneurysms; and group II--35 patients with normal coronary arteries. Patients from both groups with early acute illness, before day 5, had a significant reduction in the population of OKT3+ (p less than 0.001), OKT4+ (p less than 0.02) and OKT8+ cells (p less than 0.002), but normal OKT4/OKT8 ratios compared with age-matched control subjects. These abnormal values quickly returned to normal levels during week 2 in patients with normal coronary arteries. In contrast, patients in whom coronary aneurysms developed within 3 weeks of the onset had an imbalance between OKT4 and OKT8 during week 2, characterized by a decrease in the number of OKT8+ cells and an increase in the number of OKT4+ cells, resulting in a high OKT4/OKT8 ratio (p less than 0.01). Three patients in whom large coronary aneurysms developed had ratios higher than 4.50. Follow-up analysis of T-cell subsets from individual patients with coronary aneurysms showed that the OKT4/OKT8 ratio during the acute stage was reduced during the convalescent stage (p less than 0.005). In contrast, the ratio in patients with normal coronary arteries was normal during the course of the illness. These observations suggest that an immune regulatory process operating in coronary aneurysm formation is present.

Antibodies, Monoclonal↗
PubMed1984

[Clinical evaluation of ceftriaxone in children].

Fundamental and clinical evaluation on ceftriaxone (Ro 13-9904, CTRX) was performed and the following results were obtained. As to bacteriological efficacy, bacteria were reduced in the case with S. panama bacteremia, while they were eradicated within 2 to 5 days after CTRX administration in 2 cases with acute urinary tract infections and 1 with recurrent urinary tract infection, both caused with E. coli, and in 1 with acute urinary tract infection with P. mirabilis. The clinical efficacy was excellent in 2 cases and good in 3, the efficacy rate being 100%. No side effects were observed to require the withdrawal of CTRX.

Bacterial Infections↗
PubMed1983

Cross-sectional echocardiographic findings of anomalous origin of left coronary artery from pulmonary artery.

Anomalous origin of the left coronary artery and left ventricular myocardial hypokinesis were visualised by cross-sectional echocardiography. Significant dilatation of the right coronary artery was another important finding. Cross-sectional echocardiography appears to be useful for evaluating patients with anomalous origin of the left coronary artery from the pulmonary artery.

Coronary Vessel Anomalies↗
PubMedDate not supplied

The evaluation of corticosteroid therapy in conjunction with plasma exchange in the treatment of renal cholesterol embolic disease. A report of 5 cases.

In this report, we describe 5 patients with cholesterol atheroembolic renal failure. In 3 of the 5 patients, combined therapy with corticosteroids and plasma exchange was performed. These 3 patients survived, with 2 showing an improvement in renal function. The 2 remaining patients died of multifactorial causes. The literature on therapy for cholesterol atheroembolic renal failure is reviewed and the efficacy of combined therapy by use of corticosteroids and plasma exchange is evaluated.

Acute Kidney Injury↗