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Biomedical subjects

T Takemoto

Publications and source records attributed to T Takemoto.

At least 271 records · Page 15Linked to original sources
PubMed1976

Man, fish, and mercury on small islands in Japan.

This paper examines the differentiating patterns of subsistence activities, fish-eating habit, mercure level in human biological specimens, and the interrelation among these variables on several small Japanese islands. The catch and supply of fish vary according to patterns of division of labour on each island. The frequency of fish-eating is generally regulated by the availability of fish, and is well associated with the level of mercury in hair or red cells. Difference in variety of fish consumed has a modifying effect on the mercury level. The importance of understanding the total ecological setting relating to any environmental problem should be emphasized.

Adult↗
PubMed1976

Cytochrome P-450 in hyperplastic liver nodules during hepatocarcinogenesis with N-2-fluorenylacetamide in rats.

Amount of cytochrome P-450 in the hyperplastic liver nodules was measured during hepatocarcinogenesis with N-2-fluorenylacetamide in the rat. Amount of cytochrome P-450 in the liver microsome decreased in early stage of hepatocarcinogenesis. Concentration of cytochrome P-450 in the hyperplastic nodules and their surrounding tissues was examined, using homogenate from each of them. Its amount was significantly less in the hyperplastic nodules in the 13th week than in their surrounding tissues, and became more in hyperplastic nodules in the 19th week. The hyperplastic nodules of the animals treated with phenobarbital showed almost the same amount of cytochrome P-450 as that in the controls. Amount of cytochrome P-450 in hepatoma tissues also showed similar values as that in hyperplastic nodules.

2-Acetylaminofluorene↗