[Clinical study on hyperamylasemia due to the analysis of amylase-isoenzyme (author's transl)].
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Biomedical subjects
Publications and source records attributed to T Takemoto.
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A secular trend in age at menarche was examined for 1,333 women living in Sendai city and its surroundings by applying the birth-year cohort analysis and the cross-sectional probit analysis. The trend toward younger menarcheal ages was consistently observed by both analyses, and it started off soon after the second World War. The speed was 0.11 year/year for the observation period of 1946 to 1966.
The levels of inorganic and organic mercury in human amniotic fluid were examined in 57 Japanese pregnant women with a gestational age of 4 months to term. Inorganic mercury was detected in all but two samples, while organic mercury was found in only 30 women. The level of inorganic mercury was higher than organic mercury. The highest levels of both inorganic and organic mercury were observed in the seventh month of gestation.
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Although several investigators have reported serum alpha-fetoprotein positive gastric cancer with or without metastasis to the liver, its site of production is still unclear. We studied on the site of alpha-fetoprotein synthesis in our cases which showed remarkably high level of serum alpha-fetoprotein, and clarified the presence of alpha-fetoprotein producing gastric cancer by means of direct immunofluorescent technique. However, we also knew the hepatocytes adjacent ot the metastatic lesions could also synthesize alpha-fetoprotein, although these hepatocytes were not known whether under regeneration or degeneration. Through this study, the other carcinofetal proteins such as carcino-placental alkaline phosphatase and CEA were examined using the sera or tumor tissues. Our results will support the idea that cancer is the disease of cell differentiation.
From Diplazium donianum, makisterone A, makisterone D, and an unidentified stereoisomer of makisterone B have been isolated. The presence of two other unidentified phytoecdysones has been noted.
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