Search PubMed⌕ Search

Biomedical subjects

T Takeda

Publications and source records attributed to T Takeda.

At least 1,369 records · Page 76Linked to original sources
PubMed1976

A case of rhabdomyoma in infancy.

A case of cardiac rhabdomyoma was presented. She was diagnosed as intraatrial tumor by cardiac catheterization and angiocardiography at 7 months of age. Two months later, she was undergone open heart surgery, which revealed larger rhabdomyoma in the left atrium obstructing the mitral valve.

Cardiac Catheterization↗
PubMed1976

Evaluation of the cytological examination in mass survey of gastric cancer.

The significance of the cytological examination in the diagnosis of gastric cancer, especially in the detection of the early cancer of the stomach, was examined in 1200 cases subjected to the cytological examination in the mass survey, including 181 cases with early cancer of the stomach, 148 cases with advanced cancer of the stomach. Comparison of the detection rates of cancer in cases of surgically confirmed stomach cancer revealed that cytological examination is more reliable than endoscopic and X-ray examinations of the stomach. In only a few instances, the false negative and false positive diagnoses were made, and therefore it is important for correct diagnoses to correlate the cytological finding with the other findings. The importance of cytological examination was clearly indicated by examination of the annual detection rate of early cancer, which showed a sudden increase after the period of the introduction of the cytological method in mass survey.

Cytodiagnosis↗
PubMed1976

Cytological diagnoses of early gastric cancer.

To evaluate the clinical value of gastric cytology in the detection of stomach cancer, the results of cytological examinations in 417 cases of early cancer of the stomach in which cancer cell infiltration was limited to the mucosa or submucosa were analyzed. The cytological examination revealed positive for cancer cells in 93% of these cases, and therefore it is concluded that this method is not only useful but indispensable for the diagnosis of early cancer of the stomach. The gastric cytology proved to be more reliable than the endoscopic and X-ray examinations in terms of detection rate of the early gastric cancer. Among various cell collection methods for gastric cytology, which include the washing, abrasive and fibergastroscopic methods, the washing method under direct vision by the use of fiberscope showed the highest value of positivity (92.8%) in the cases of early cancer of the stomach. With the help of endoscopic guidance and biopsy techniques, the cytological examination further increased its reliability and ability in the detection of early gastric cancer. Cancer lesions even smaller than 1 cm can now be correctly diagnosed by the gastric cytology.

Cytodiagnosis↗
PubMed1976

Experimental studies on connective tissue of the capsular ligament. Influences of aging and sex hormones.

Influences of aging and sex hormones on connective tissue metabolism in the hip joint capsule of Wistar rats were analyzed both biochemically and morphologically. As age advanced, collagen content and collagen fibril diameter of the hip joint capsule tended to increase gradually in both sexes until sexual maturation was reached. Collagen content was significantly greater in males than in females after sexual maturation. The collagen content and fibril diameter were considerably increased by ovariectomy and significantly decreased by the administration of estrogen, or estrogen combined with progesterone, whereas they were significantly increased by the administration of testosterone in orchiectomized male rats.

Aging↗
PubMed1976

Effect of vitamin B6 deficiency on collagen metabolism in rats.

The effects of VB6 deficiency on collagen metabolism were studied using young and adult rats. It was observed in VB6 deficient rats, that both the amount of urinary hydroxyproline and salt soluble fraction of skin collagen decreased. Furthermore, decrease of the alpha-component and increase of the beta-component were also found in the soluble collagen. However, the activity of plasma amine oxidase was lower and the aldehyde content in the acid soluble collagen were also lower than the control group. These changes were revealed more clearly in young growing rats than in adult rats. Based on these results, it may be that VB6 participates in the allysine (alpha-amino-adipic-delta-semialdehyde) formation which is considered as the first step of collagen maturation and also in the synthesis of protocollagen peptide chains.

2-Aminoadipic Acid↗
PubMed1976

Studies of factors influencing alveolar lining layer formation in lung homogenate: further isolation and identification of interfering materials.

Materials which inhibit the formation of stable alveolar lining layer by lung surfactant were investigated with the pig lung homogenate. The inhibitory activity was assessed by the bubble stability test on the bubbles formed by mechanical agitation of a mixture of surface active fraction from lung homogenate and inhibitory materials. The most active inhibitory material was identified as free cholesterol. Free fatty acids had a remarkable inhibitory activity. By modified Wilhelmy balance, it was demonstrated that the addition of free cholesterol to the surface active fraction delayed the formation of the stable surface membrane and at a larger dosage it inhibited the lowering the surface tension at the minimum surface area. The significance of this phenomenon in pathological lungs was briefly discussed.

Animals↗
PubMed1975

Experimental studies on the effect of aging and endocrine control on collagen formation in various organs.

Physiological changes with advancing age of collagen content, fiber and fibril sizes in some connective tissues, the morphological profiles and enzyme histochemical activities of fibroblasts in different organs. and the effect of gonadectomy, adrenalectomy, hypophysectomy and their hormone replacement on the collagen and fibroblasts were studied using DDD, C57BL/6J, A/Jax, DW/J mice and Wistar rats. It was suggested that connective tissue in these organs was under the specific control of endocrine organs such as gonads, adrenals and the pituitary and that these controls might be effected through their hormonal effects on the specifically differentiated fibroblast localized in different organs and tissue.

Adrenal Cortex Hormones↗
PubMed1975

Long-term prognosis of renovascular hypertension: comparative study in operated and non-operated patients.

Long-term prognosis of renovascular hypertension has been studied in 56 patients. Twenty-nine patients underwent surgical treatment and 27 patients were not operated upon for various reason. Initial severity of hypertension in the operated group was nearly comparable to that of the non-operated group. Average of observation periods in each group is 5.8 and 5.9 years respectively, and the longest follow-up period has been up to 12 years. Hypertension cured or improved in 25 cases of the operated group. Antihypertensive therapy was effective in 7 of the medically treated patients. During the entire observation periods, 2 cases of the operated and 10 cases of the non-operated group died. Seven deaths of the non-operated group seemed to be causally related to hypertension. It is concluded that long-term prognosis of operated patients is significantly improved as compared with that of patients whose renovascular hypertension could not be treated surgically. Prevelence of aortitis (Takayasu's disease) as a cause of renovascular hypertension is a particular problem in our series because extensive and complicated renovascular lesions may make surgical intervention difficult in some patients.

Cerebral Hemorrhage↗