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Biomedical subjects

T Sugai

Publications and source records attributed to T Sugai.

At least 163 records · Page 9Linked to original sources

The mode of growth of eccrine duct milia.

Light and electron microscopic studies were performed utilizing serial sections in 10 patients with secondary milia to clarify the incidence of eccrine duct milia and to demonstrate the life history of the milia. Out of 69 milia after blistering taken from 8 patients, 52 were found to connect with the eccrine sweat duct (75.4%) while only 1 connected with the hair follicle (1.5%). In the control group, of 4 milia taken from 2 patients, 2 were found to connect with the eccrine sweat duct and 1 with the hair follicle. Various degrees of milium formation were observed ranging from incomplete and having either concave-shape, U-shape, capped U-shape, or O-shape. The eccrine duct milia in all types possess structures resembling the epidermal sweat duct unit. The epithelial cells constituting the recess or cyst differ from epidermal cells.

Cysts↗

Hypersensitivity to hydrogenated lanolin.

The number of patients with dermatitis from applied betamethasone-17-valerate ointment, which incorporated hydrogenated lanolin, rapidly increased in Japan after 1971. On patch testing, the incidence of hypersensitivity to hydrogenated lanolin is significantly higher than to anhydrous lanolin at the 1% level, that is 5.20% (26/502) with the former and 1.99% (10/502) with the latter, although sensitivity to both materials is significantly related at the 0.5% level. The possible explanations considered are that hydrogenated lanolin contains three main allergens: the first is a group of lanolin alcohols which are the common eczematogens in anhydrous lanolin; the second refers to the products of hydrogenation, composed of saturated, easily oxidized, organic substances of low molecular weight; and the third refers to traces of nickel, copper and chromium, as a result of contamination in the hydrogenation process.

Adult↗