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Biomedical subjects

T Sharma

Publications and source records attributed to T Sharma.

At least 181 records · Page 10Linked to original sources
PubMed1977

Preferential late replication of one of the two morphologically distinguishable X-chromosomes in a female muntjac.

In a female barking deer, Muntiacus muntjak, whose 2 X-chromosomes are mutually distinguishable from each other, one X has been found to be late replicating in 57.8% cells compared to the other which is late replicating in 42.2% cells. These data are suggestive of preferential inactivation of one X-chromosome. These findings have been discussed in the light of Lyon's hypothesis of random X-inactivation in eutherian mammals.

Animals↗
PubMed1976

Unique multiple sex chromosomes of the tree mouse Vandeleuria o. oleracea: identification of X1 and X2.

The tree mouse Vandeleuria o. oleracea has an odd diploid chromosome complement (2n = 29 female/male) accompanied by a unique multiple sex-chromosome mechanism (X1X2Ymale/X1X1X2female). In the present paper the sex chromosomes have been identified unequivocally with the help of G-banding and DNA replication patterns which confirm our earlier suggestion that the X1 is smaller in size than the simple mammalian X, and also that the combined sizes of the X1 and X2 (3-8 and 1-7 per cent respectively) approximate to the size of the conservative mammalian X (5 per cent). It is proposed that the mammalian X has attained a minimum functional size so that further reduction is not tolerated.

Animals↗