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Biomedical subjects

T Scott

Publications and source records attributed to T Scott.

At least 73 records · Page 4Linked to original sources
PubMed1987

Internal pudendal pseudoaneurysm complicating an ischial pressure sore.

A 23-year-old paraplegic patient experienced two episodes of substantial hemorrhage from an ischial pressure sore. Computed tomography showed that the wound extended into the pelvis and retroperitoneum, and arteriography demonstrated a pseudoaneurysm of the internal pudendal artery. The artery was selectively embolized, permitting debridement and flap coverage uncomplicated by bleeding. Bleeding from a pelvic extension of a pressure sore can be a catastrophic combination of distorted anatomy and relatively inaccessible vessels. As in hemorrhagic complications of pelvic trauma, tumors, and radiation, arteriography and transcatheter embolization can localize and control the source of bleeding.

Adult↗
PubMed1987

Phonological similarity effects, memory span and developmental reading disorders: the nature of the relationship.

Eight-and 11-year-old poor readers of average and below average intelligence carried out a visually presented immediate memory task, recalling strings of similar- and dissimilar-sounding letters. Task difficulty was adjusted for each child by determining memory span for the dissimilar items prior to the memory task. All poor reader groups recalled significantly more dissimilar- than similar-sounding items, and the magnitude of these effects was comparable to those shown by their chronological and reading age controls. A close association was found between memory span and reading age, such that average intelligence poor readers had memory spans indistinguishable from those of their reading age controls. Furthermore, a highly significant correlation was found between memory span and reading age. However, it was concluded that this relationship could not be primarily due to a substantial immediate memory component in word recognition as the below average intelligence poor readers had poorer memory spans than the brighter poor readers, yet they had very similar reading ages. Additionally, a weaker association was found between memory span and non-word reading than between memory span and word reading. It was hypothesized that recognition difficulties may be the primary problem underlying both poor word recognition and immediate memory impairments in children with reading disorders.

Child↗
PubMed1986

Gliomyosarcoma. Report of a case of rhabdomyosarcoma arising in a malignant glioma.

The development of sarcoma within a glioblastoma is a well recognised complication: in the majority of cases it is a fibro-sarcoma originating in the tissues of the proliferating hyperplastic blood vessels. In the case described here the tumour is a rhabdomyosarcoma, apparently derived from abnormal prolific vascular mesenchyme. Only one comparable example has been recorded previously.

Brain Neoplasms↗
PubMed1985

Microglia in teratomas.

Using an ammoniacal silver nitrate stain, we have demonstrated typical microglial cells in three teratomas. Microglia appeared identical to their counterparts in the mature human brain, both resting and slightly hypertrophic types being present in differentiated nervous tissue, which also comprised astrocytes, neurones and ependyma. The implications of the presence of microglia with ectodermal derivatives in teratomas are discussed.

Adolescent↗
PubMed1985

Effect of thiouracil-induced hypothyroidism on the humoral immunity of New Hampshire chickens.

Two experiments were conducted to examine the effects of feeding a diet containing .1% thiouracil to two lines of New Hampshire chickens differing in growth rate and relative bursa size. Body weight, serum 3,5,3'-triiodothyronine, and thyroxine were reduced by the thiouracil treatment. The primary total anti-sheep red blood cell (SRBC) titer in Experiment 1 was higher for thiouracil-fed (TF) chicks at 7 days postprimary immunization (PPI). In Experiment 2, the total anti-SRBC titers were higher for control chicks 3 days PPI; but from 5 to 10 days PPI, TF chicks had higher titers. During the secondary response in both experiments, the total anti-SRBC titers were not consistently higher for one dietary group over the other from 3 to 10 days postimmunization. Mercaptoethanol-resistant antibody titers were not significantly different between the two dietary groups in either experiment during the primary and secondary responses. Thiouracil-fed chicks had higher immunoglobulin G (IgG) and M (IgM) concentrations in serum during both the primary and secondary responses in Experiment 2. Although there was no genotype effect on antibody production to SRBC, serum immunoglobulins were different between lines. Small bursa line (SBL) chickens had higher serum IgG while the IgM concentrations of chicks from the Lester J. Dreesen strain were greater than those of SBL.

Animals↗
PubMed1985

Do we need to repeat prescribe?

In an attempt to rationalize repeat prescribing and patient review, the whole concept of repeat prescriptions was questioned and discarded as being unnecessary. The reason for the audit and some of the benefits and drawbacks are reported.

Drug Prescriptions↗
PubMed1983

Electron-microscopical study of a Rathke's cleft cyst.

The electron-microscopical appearance of a Rathke's cleft cyst is described. The cyst lining is seen to consist predominantly of secretory columnar epithelium, both ciliated and non-ciliated. There are also epidermoid cells occurring singly or in squamae. The histogenesis of Rathke's cleft cysts, in relation to craniopharyngiomas, is discussed.

Adolescent↗
PubMed1980

A note on the nature of eosinophilic granular bodies in astrocytic gliomas.

Eosinophilic granular bodies are a characteristic microscopical finding in certain gliomas of astrocytic type. The nature of these structures has been the subject of debate. The finding of a positive reaction for glial fibrillary acidic protein confirms the astrocytic nature of this material.

Astrocytes↗
PubMed1980

Silver deposition in arteriolar basal laminae in the cerebral cortex of argyric rats.

Electron microscopy of the parietal cortex and subcortical white matter of argyric rat brain revealed extremely fine 10--15 nm deposits of silver within the basal laminae of some arterioles. Stab-wound injury to argyric rats resulted in increased silver deposits in arteriolar basal laminae but not in any deposition of silver in the brain parenchyma.

Animals↗
PubMed1978

An ultrastructure study of cerebellar lesions induced in mice by three inoculations of avirulent Semliki forest virus.

An ultrastructural study of cerebellar lesions involving axonal and myelin degeneration induced in adult Swiss A2G mice by 3 intraperitoneal inoculations of avirulent Semliki Forest virus is described. Cerebellar white matter samples examined by light and electron miscroscopy 21 days after the first virus infection revealed microcystic areas, degenerating axons, macrophages containing myelin debris as well as normal elements. By light microscopy foci of myelin loss were apparent. At 28 days groups of degenerating axons were apparent in the white matter. No virus was seen in any of the sections.

Animals↗